I-alkaline phosphatase: iyini nokuthi kungani iphakeme noma iphansi

-Delile

• Yenzelwe ini
• 1.I-alkaline phosphatase ephezulu
• 2. I-phosphatase ene-alkaline ephansi
• Ukwenza isivivinyo nini
• Kwenziwa kanjani ukuhlolwa
• Amanani ayizethenjwa

I-alkaline phosphatase iyi-enzyme ekhona ezicutshini ezahlukahlukene zomzimba, iba ngobuningi obukhulu kumaseli wemigudu yenyongo, okuyiziteshi ezihola inyongo kusukela ngaphakathi kwesibindi iye emathunjini, okwenza ukugaya amafutha, nasemathanjeni, akhiqizwa amaseli abandakanyeka ekwakhekeni nasekugcinweni kwawo.

Ukuhlolwa kwe-alkaline phosphatase kuvame ukusetshenziselwa ukuphenya izifo esibindini noma emathanjeni, lapho izimpawu nezimpawu zikhona njengobuhlungu esiswini, umchamo omnyama, i-jaundice noma ukukhubazeka kwamathambo nobuhlungu, isibonelo. Kungenziwa futhi njengokuhlolwa okujwayelekile, kanye nezinye izivivinyo, ukuze kuhlolwe impilo yesibindi.

Yize ngamanani aphansi, i-alkaline phosphatase nayo ikhona ku-placenta, izinso namathumbu ngakho-ke ingaphakanyiswa ekukhulelweni noma ezimweni zokuhluleka kwezinso.

Yenzelwe ini

Ukuhlolwa kwe-alkaline phosphatase kusetshenziselwa ukuphenya ukuphazamiseka kwesibindi noma kwethambo futhi umphumela wayo ungakhomba:

1.I-alkaline phosphatase ephezulu

I-alkaline phosphatase ingaphakanyiswa lapho kunezinkinga ngesibindi njenge:

• Ukuvinjelwa kokugeleza kwenyongo, okubangelwa yinyongo noma umdlavuza, okuvimba imigudu eholela enyongweni emathunjini;

• I-hepatitis, okuwukuvuvukala kwesibindi okungabangelwa amagciwane, amagciwane noma imikhiqizo enobuthi;

• I-Cirrhosis, okuyisifo esiholela ekubhujisweni kwesibindi;

• Ukusetshenziswa kokudla okunamafutha;

• Ukungasebenzi kahle kwezinso.

Ngaphezu kwalokho, le enzyme ingaba phezulu kakhulu ezimeni lapho kukhona khona ukwanda komsebenzi wokwakheka kwamathambo, njengakwezinye izinhlobo zomdlavuza wamathambo noma kubantu abanesifo sikaPaget, okuyisifo esivezwa ukukhula okungajwayelekile kwethambo elithile izingxenye. Funda kabanzi ngesifo sikaPaget.

Izinguquko ezincane nazo zingenzeka ngezikhathi zokuphulukiswa kokuphuka, ukukhulelwa, i-AIDS, ukutheleleka kwamathumbu, i-hyperthyroidism, i-Hodgkin's lymphoma, noma ngisho nangemva kokudla okunamafutha amaningi.

2. I-phosphatase ene-alkaline ephansi

Amazinga e-alkaline phosphatase awavamile ukuba aphansi, kepha le enzyme ingahle yehle kulezi zimo ezilandelayo:

• I-Hypophosphatasia, okuyisifo sofuzo esidala ukukhubazeka nokuqhekeka kwamathambo;

• Ukungondleki kahle;

• Ukushoda kweMagnesium;

• I-Hypothyroidism;

• Uhudo olunzima;

• I-anemia enamandla.

Ngaphezu kwalokho, amanye amakhambi afana nephilisi lokulawula ukuzalwa kanye namakhambi okwelapha ama-hormone asetshenziswa ngesikhathi sokunqamuka kokuya esikhathini nakho kungadala ukwehla okuncane emazingeni e-alkaline phosphatase.

Ukwenza isivivinyo nini

Ukuhlolwa kwe-alkaline phosphatase kufanele kwenziwe lapho izimpawu nezimpawu zokuphazamiseka kwesibindi ezifana nesisu esikhulisiwe, ubuhlungu ohlangothini lwesokunene sesisu, i-jaundice, umchamo omnyama, izitulo ezikhanyayo kanye nokulunywa okujwayelekile kukhona.

Ngaphezu kwalokho, lokhu kuhlolwa kukhonjiswa nakubantu abanezimpawu nezimpawu ezingeni lamathambo njengokuqaqamba kwamathambo okujwayelekile, ukukhubazeka kwamathambo noma abahlukumezekile.

Kwenziwa kanjani ukuhlolwa

Ukuhlolwa kungenziwa elabhoratri, lapho uchwepheshe wezokunakekelwa kwempilo ethatha khona cishe u-5 ml wesampula yegazi emthanjeni engalweni, efakwa esitsheni esivaliwe, ukuze ihlaziywe.

Amanani ayizethenjwa

Amanani esithenjwa esivivinyo se-alkaline phosphatase ayahluka ngobudala, ngenxa yokukhula:

Izingane nentsha:

• <Iminyaka emibili: 85 - 235 U / L
• Iminyaka emi-2 kuya kwengu-8: 65 - 210 U / L
• Iminyaka eyi-9 kuye kwengu-15: 60 - 300 U / L.
• Iminyaka eyi-16 kuya kwengama-21: 30 - 200 U / L.

Abantu abadala:

• 46 kuya ku-120 U / L.

Ekukhulelweni, amanani egazi we-alkaline phosphatase angashintshwa kancane, ngenxa yokukhula kwengane futhi ngoba le enzyme nayo ikhona ku-placenta.

Kanye nalolu vivinyo, kungenziwa futhi ukuhlolwa kwamanye ama-enzyme atholakala esibindi njenge-alanine aminotransferase, i-aspartate aminotransferase, i-gamma glutamyl transpeptidase nama-bilirubins, ukuhlolwa kwe-imaging noma i-biopsy yesibindi. Bona ukuthi lezi zivivinyo zenziwa kanjani.