I-lymphoma eyinhloko yobuchopho

I-lymphoma eyinhloko yobuchopho umdlavuza wamaseli amhlophe egazi aqala ebuchosheni.

Isizathu se-primary brain lymphoma asaziwa.

Abantu abanamasosha omzimba abuthakathaka basengozini enkulu ye-lymphoma eyinhloko yobuchopho. Izimbangela ezivamile zokuzivikela komzimba zibuthakathaka zibandakanya i-HIV / AIDS kanye nokuba nokufakelwa komzimba (ikakhulukazi ukufakelwa inhliziyo).

I-lymphoma eyinhloko yobuchopho ingaxhunyaniswa ne-Epstein-Barr Virus (EBV), ikakhulukazi kubantu abane-HIV / AIDS. I-EBV yigciwane elibanga i-mononucleosis.

I-primary brain lymphoma ivame kakhulu kubantu abaneminyaka yobudala engama-45 kuya kwengama-70. Izinga lobuchopho obuyinhloko i-lymphoma liyakhuphuka. Cishe iziguli ezintsha ze-1,500 zitholakala zine-primary brain lymphoma minyaka yonke e-United States.

Izimpawu ze-primary brain lymphoma zingafaka noma yikuphi okulandelayo:

• Izinguquko enkulumweni noma embonweni
• Ukudideka noma ukusangana
• Ukuquleka
• Ukuphathwa ikhanda, isicanucanu, noma ukuhlanza
• Uncike ohlangothini olulodwa lapho uhamba
• Ubuthakathaka ezandleni noma ukulahleka kokuxhumana
• Ubuntofontofo kushisa, kubanda, nobuhlungu
• Ubuntu buyashintsha
• Ukwehla kwesisindo

Ukuhlolwa okulandelayo kungenziwa ukusiza ukuthola i-lymphoma eyinhloko yobuchopho:

• I-biopsy yesimila sobuchopho
• Iskena se-Head CT, i-PET scan noma i-MRI
• Thepha umgogodla (ukubhoboza i-lumbar)

I-lymphoma eyinhloko yobuchopho ivame ukwelashwa kuqala ngama-corticosteroids. Le mithi isetshenziselwa ukulawula ukuvuvukala nokwenza ngcono izimpawu. Ukwelashwa okuyinhloko ukwelashwa ngamakhemikhali.

Abantu abancane bangathola i-chemotherapy ephezulu, okungenzeka ilandelwe ukufakelwa kwe-stem cell autologous.

Ukwelashwa ngemisebe kobuchopho bonke kungenziwa ngemuva kokwelashwa ngamakhemikhali.

Ukuqinisa amasosha omzimba, njengalabo abane-HIV / AIDS, nakho kungazama.

Wena nomhlinzeki wakho wezokunakekelwa kwempilo kungadingeka ukuthi niphathe ezinye izinto ezikukhathazayo ngesikhathi sokwelapha, kufaka phakathi:

• Ukuba ne-chemotherapy ekhaya
• Ukuphatha izilwane ezifuywayo ngesikhathi se-chemotherapy
• Izinkinga zokopha
• Umlomo owomile
• Ukudla amakhalori anele
• Ukudla okuphephile ngesikhathi sokwelashwa komdlavuza

Ngaphandle kokwelashwa, abantu abane-primary brain lymphoma basinda ngaphansi kwezinyanga eziyisithupha. Lapho welashwa ngamakhemikhali, isigamu seziguli sizoxolelwa ngemuva kweminyaka eyi-10 sitholakele. Ukusinda kungathuthuka ngokufakelwa kwe-stem cell autologous.

Izinkinga ezingaba khona zifaka:

• Imiphumela emibi ye-Chemotherapy, kufaka phakathi ukubalwa kwegazi okuphansi
• Imiphumela emibi ye-radiation, kufaka phakathi ukudideka, ikhanda, izinkinga zesistimu yezinzwa (neurologic), kanye nokufa kwezicubu
• Buyisela (ukuphindaphinda) kwe-lymphoma

I-Brain lymphoma; ICerebral lymphoma; I-lymphoma eyinhloko yesistimu yezinzwa eziphakathi; I-PCNSL; I-Lymphoma - B-cell lymphoma, ubuchopho

• Ubuchopho
• I-MRI yobuchopho

I-Baehring JM, iHochberg FH. Izimila zesistimu yezinzwa eyinhloko kubantu abadala. Ku: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, ama-eds. I-Neurology kaBradley ekwenziweni kwemitholampilo. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2016: isahluko 74.

IGrommes C, iDeAngelis LM. I-CNS primary lymphoma. J Clin Oncol. 2017; 35 (21): 2410 - 2418. I-PMID: 28640701 pubmed.ncbi.nlm.nih.gov/28640701/.

Iwebhusayithi yeNational Cancer Institute. Ukwelashwa okuyisisekelo kwe-CNS lymphoma (PDQ) - inguqulo yezobuchwepheshe yezempilo. www.cancer.gov/cancertopics/pdq/treatment/primary-CNS-lymphoma/HealthProfessional. Kubuyekezwe uMeyi 24, 2019. Kufinyelelwe ngoFebhuwari 7, 2020.

Iwebhusayithi ye-National Comprehensive Cancer Network. Imikhombandlela ye-NCCN yokwenza imitholampilo ku-oncology (imihlahlandlela ye-NCCN): umdlavuza wesistimu yezinzwa. Inguqulo 2.2020. www.nccn.org/professionals/physician_gls/pdf/cns.pdf. Kubuyekezwe u-Ephreli 30, 2020. Kufinyelelwe ngo-Agasti 3, 2020.