I-adrenocortical carcinoma

I-Adrenocortical carcinoma (ACC) umdlavuza wezindlala ze-adrenal. Izindlala ze-adrenal yizindlala ezimbili ezimise unxantathu. Indlala eyodwa itholakala ngaphezulu kwesinso ngasinye.

I-ACC ivame kakhulu ezinganeni ezineminyaka engaphansi kwengu-5 ubudala nakubantu abadala abaneminyaka engama-40 nengama-50.

Isimo singase sixhunyaniswe nesifo somdlavuza esidluliselwa ngemindeni (esizuzwe njengefa). Bobabili abesilisa nabesifazane bangaba nalesi sifo.

I-ACC ingakhiqiza ama-hormone i-cortisol, i-aldosterone, i-estrogen, noma i-testosterone, kanye namanye ama-hormone. Kwabesifazane isimila sivame ukukhipha la mahomoni, angaholela ezinhlotsheni zesilisa.

I-ACC ayivamile kakhulu. Imbangela ayaziwa.

Izimpawu zokwanda kwe-cortisol noma amanye ama-hormone adrenal gland angafaka:

• Amafutha, i-hump eyindilinga ephezulu ngemuva ngemuva nje kwentamo (inyathi)
• Ubuso obuvuthiwe, obuyindilinga obunezihlathi eziphikisayo (ubuso benyanga)
• Ukukhuluphala ngokweqile
• Ukukhula okumile (isiqu esifushane)
• I-Virilization - ukuvela kwezici zesilisa, kufaka phakathi izinwele ezandisiwe zomzimba (ikakhulukazi ebusweni), izinwele ze-pubic, induna, ukujula kwezwi, kanye ne-clitoris enwetshiwe (abesifazane)

Izimpawu ze-aldosterone eyandisiwe ziyefana nezimpawu ze-potassium ephansi, futhi zifaka:

• Amajaqamba emisipha
• Ubuthakathaka
• Ubuhlungu esiswini

Umhlinzeki wezokunakekelwa kwempilo uzokwenza ukuhlolwa komzimba abuze ngezimpawu zakho.

Ukuhlolwa kwegazi kuzokwenziwa ukuhlola amazinga ama-hormone:

• Izinga le-ACTH lizoba liphansi.
• Izinga le-Aldosterone lizobe liphakeme.
• Izinga leCortisol lizophakama.
• Izinga le-Potassium lizoba liphansi.
• Amahomoni abesilisa noma abesifazane angaphakama ngokungajwayelekile.

Ukulingisa ukuhlolwa kwesisu kungafaka:

• I-Ultrasound
• Iskena se-CT
• I-MRI
• Ukuskena kwe-PET

Ukwelashwa okuyisisekelo ukuhlinzwa ukuze kususwe isimila. I-ACC kungenzeka ingathuthuki nge-chemotherapy. Imithi inganikezwa ukunciphisa ukukhiqizwa kwe-cortisol, edala izimpawu eziningi.

Umphumela uncike ekutheni ukuxilongwa kwenziwa kusenesikhathi kangakanani nokuthi ngabe isimila sesisakazekile (senziwe imastastasized). Izimila ezisakazekile ngokuvamile ziholela ekufeni kungakapheli unyaka owodwa kuya kwemithathu.

Isimila singasakazekela esibindini, emathanjeni, emaphashini, noma kwezinye izindawo.

Shayela umhlinzeki wakho uma wena noma ingane yakho unezimpawu ze-ACC, i-Cushing syndrome, noma ukwehluleka ukukhula.

Isimila - adrenal; I-ACC - adrenal

• Izindlala ze-Endocrine
• I-adrenal metastases - i-CT scan
• I-Adrenal Tumor - CT

U-Allolio B, Fassnacht M. Adrenocortical carcinoma. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 107.

Iwebhusayithi yeNational Cancer Institute. Ukwelashwa kwe-Adrenocortical carcinoma (Adult) (PDQ) - inguqulo yezempilo. www.cancer.gov/types/adrenocortical/hp/adrenocortical-treatment-pdq. Kubuyekezwe ngoNovemba 13, 2019. Kufinyelelwe ngo-Okthoba 14, 2020.