Igciwane lesibindi le-peroxidase

Ama-microsomes atholakala ngaphakathi kwamaseli wegilo. Umzimba ukhiqiza ama-antibody kuma-microsomes lapho kube nomonakalo kumaseli wegilo. Ukuhlolwa kwe-antithyroid microsomal antibody kukala la ma-antibody egazini.

Kudingeka isampula yegazi.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlolwa kwenziwa ukuqinisekisa imbangela yezinkinga ze-thyroid, kufaka phakathi i-Hashimoto thyroiditis.

Isivivinyo sisetshenziselwa ukuthola ukuthi isifo sokuzivikela komzimba noma i-autoimmune siyalimaza yini igilo.

Ukuhlolwa okungekuhle kusho ukuthi imiphumela ijwayelekile.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezihlukile. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Ukuhlolwa okuqondile kungabangelwa:

• I-Granulomatous thyroiditis (ukusabela komzimba ekuguleni kwe-thyroid okuvame ukulandela ukutheleleka okuphezulu okuphefumulayo)
• I-Hashimoto thyroiditis (ukusabela kwamasosha omzimba ngokulwa nendlala yegilo)

Amazinga aphezulu ala ma-antibody nawo axhumene nengozi eyengeziwe yoku:

• Ukuphuphuma kwesisu
• I-Preeclampsia (umfutho wegazi ophakeme namaprotheni emchameni ngemuva kweviki lama-20 lokukhulelwa)
• Ukuzalwa ngaphambi kwesikhathi
• Ukwehluleka kokukhulelwa kwe-in vitro

Okubalulekile: Umphumela omuhle awusho ngaso sonke isikhathi ukuthi unesimo se-thyroid noma ukuthi udinga ukwelashwa kwe-thyroid yakho. Umphumela omuhle ungasho ukuthi unethuba eliphakeme lokuthuthukisa isifo se-thyroid ngokuzayo. Lokhu kuvame ukuhlotshaniswa nomlando womndeni wesifo se-thyroid.

Ama-antibodies we-Antithyroid microsomal angabonakala egazini lakho uma unezinye izimo ezizimele, kufaka phakathi:

• I-autoimmune hemolytic anemia
• I-hepatitis ezenzakalelayo
• Isifo se-adrenal autoimmune
• Isifo samathambo
• Isifo seSjögren
• Uhlelo lupus erythematosus

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthola isampula yegazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Igciwane lesandulela ngculaza le-antimicrosomal; I-antibody ye-Antimicrosomal; I-antibody ye-Microsomal; I-Antithyroid microsomal antibody; TPOAb; I-anti-TPO antibody

• Ukuhlolwa kwegazi

U-Chang AY, u-Auchus RJ. Ukuphazamiseka kwe-Endocrine okuthinta ukukhiqizwa kabusha. Ku: Strauss JF, Barbieri RL, ama-eds. I-Endocrinology Yokuzala Yen & Jaffe. Umhlaka 8. IPhiladelphia, PA: Elsevier; 2019: isahluko 24.

IChernecky CC, iBerger BJ. Indlala ye-peroxidase (i-TPO, i-antimicrosomal antibody, i-antithyroid microsomal antibody) i-antibody - igazi. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelebhu kanye Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 1080-1081.

UGuber HA, uFarag AF. Ukuhlolwa komsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 24.

USalvatore D, uCohen R, uKopp PA, uLarsen PR. I-pathophysiology ye-thyroid nokuhlolwa kokuxilongwa. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 11.

I-Weiss RE, Refetoff S. Ukuhlolwa komsebenzi we-Thyroid. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 78.