I-Estrogen neBazedoxifene

-Delile

• Ngaphambi kokuthatha i-estrogen ne-bazedoxifene,
• I-Estrogen ne-bazedoxifene kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Ukuthatha i-estrogen kwandisa ingozi yokuthi uzoba nomdlavuza we-endometrium (umdlavuza wolwelwesi lwesibeletho [isibeletho] ngesikhathi sokwelashwa kwakho noma kuze kube yiminyaka eyi-15 ngemuva kokwelashwa kwakho, uma ungazange uthole i-hysterectomy (ukuhlinzwa ukukhipha isibeletho [isibeletho ]). Uma uthatha isikhathi eside i-estrogen, iba sengozini enkulu yokuthi uzoba nomdlavuza we-endometrium. Ukuthatha i-bazedoxifene kanye ne-estrogen kunganciphisa ingozi yokuthi uzoba nomdlavuza we-endometrium. Ungathathi noma imiphi eminye imishanguzo equkethe i-estrogen ngesikhathi sokwelashwa kwakho ngoba lokhu kungakhuphula ubungozi bokuba nomdlavuza we-endometrium. Ngaphambi kokuba uqale ukuthatha i-estrogen, tshela udokotela wakho uma uke waba nomdlavuza noma wake waba negazi elingajwayelekile esithweni sangasese. Udokotela wakho angakutshela ukuthi ungathathi i-estrogen ne-bazedoxifene uma wopha ngokweqile esithweni sangasese sowesifazane. Udokotela wakho uzokuqapha eduze ngenxa yengozi yokuthi uzoba nomdlavuza we-endometrial ngesikhathi noma ngemuva kokwelashwa kwakho. Shayela udokotela wakho ngokushesha uma unokuphuma okungavamile noma okungajwayelekile ngesikhathi sowelashwa nge-estrogen.

Abesifazane abathatha i-estrogen bangaba nengozi enkulu yokuba nokushaywa unhlangothi noma ukuba namahlwili egazi emaphashini noma emilenzeni, umdlavuza webele, kanye nokuwohloka komqondo (ukulahlekelwa amandla okucabanga, ukufunda nokuqonda) kunabesifazane abangathathi i-estrogen. Tshela udokotela wakho uma wena noma omunye emndenini wakho uke waba namahlwili egazi noma umdlavuza webele, uma uke wahlaselwa yisifo senhliziyo noma isifo sohlangothi, noma uma unanoma isiphi isimo esandisa ingozi yokuthi uzoba namahlule egazi. Udokotela wakho angakutshela ukuthi ungathathi i-estrogen ne-bazedoxifene. Phinda utshele udokotela wakho uma ubhema noma usebenzisa ugwayi, futhi uma uke waba nomfutho wegazi ophakeme noma owake waba nawo, amazinga aphezulu egazi e-cholesterol noma amafutha, isifo sikashukela, isifo senhliziyo, i-lupus (isimo lapho umzimba uhlasela izicubu zawo ezidala umonakalo nokuvuvukala), izigaxa zesifuba, noma i-mammogram engajwayelekile (i-x-ray yebele esetshenziselwe ukuthola umdlavuza webele).

Lezi zimpawu ezilandelayo zingaba yizimpawu zezimo ezibucayi zezempilo ezibalwe ngenhla. Shayela udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo ngenkathi uthatha i-estrogen ne-bazedoxifene: ikhanda elibuhlungu, elibuhlungu; ukuhlanza okungazelelwe, okunzima; izinkinga zokukhuluma; isiyezi noma ukuquleka; ukulahleka okungazelelwe okuphelele noma okuncane kombono; ukubona kabili; ubuthakathaka noma ukuba ndikindiki kwengalo noma komlenze; ukuchoboza ubuhlungu besifuba noma isisindo sesifuba; ukukhwehlela igazi; ukuphefumula ngokuzumayo; ubunzima bokucabanga kahle, ukukhumbula, noma ukufunda izinto ezintsha; izigaxa zamabele noma ezinye izinguquko zamabele; khulula izingono; noma ubuhlungu, ubumnene, noma ubomvu emlenzeni owodwa.

Kufanele uhlole amabele akho njalo ngenyanga futhi une-mammogram kanye nokuhlolwa kwebele okwenziwa ngudokotela minyaka yonke ukusiza ukuthola umdlavuza webele ngokushesha ngangokunokwenzeka. Udokotela wakho uzokutshela ukuthi ungawahlola kanjani kahle amabele akho nokuthi ngabe kufanele ube nalezi zivivinyo kaningi ngaphezu kwesisodwa ngonyaka ngenxa yomlando wakho wezempilo noma womndeni.

Tshela udokotela wakho uma uhlinzwa noma uzophumula embhedeni. Udokotela wakho angakutshela ukuthi uyeke ukuthatha i-estrogen ne-bazedoxifene amasonto amane kuya kwayisithupha ngaphambi kokuhlinzwa noma ukuphumula kombhede ukunciphisa ubungozi bokuthi uzoba namahlule egazi. Uma uzohamba, qiniseka ukuthi uvuka uzulazule ngezikhathi ezithile ngoba ukuhlala phansi isikhathi eside kungakhuphula ubungozi bokuthi ube namahlule egazi.

Ungathatha izinyathelo ukunciphisa ingozi yokuthi uzoba nenkinga enkulu yezempilo ngenkathi uthatha i-estrogen. I-Estrogen ne-bazedoxifene akufanele isetshenziselwe ukuvimbela isifo senhliziyo, ukuhlaselwa yinhliziyo, ukushaywa unhlangothi, noma ukuwohloka komqondo. Ukuthatha umthamo ophansi kakhulu we-estrogen olawula izimpawu zakho futhi uthathe i-estrogen kuphela uma kudingeka kungasiza ekunciphiseni lezi zingozi. Khuluma nodokotela wakho ngezikhathi ezithile ukunquma ukuthi kufanele yini uthathe umthamo ophansi we-estrogen noma uyeke ukuthatha umuthi.

Khuluma nodokotela wakho njalo ngezingozi zokuthatha i-estrogen ne-bazedoxifene.

Amathebulethi e-Estrogen ne-bazedoxifene asetshenziselwa ukwelapha ukushisa (imizwa efudumele engazelelwe, ikakhulukazi ebusweni, entanyeni, nasesifubeni) kwabesifazane ababhekene nokunqamuka kokuya esikhathini (isigaba sempilo lapho izikhathi zokuya esikhathini ziba kancane kakhulu futhi ziyayeka futhi abesifazane bangathola ezinye izimpawu nezinguquko zomzimba). Amaphilisi e-Estrogen ne-bazedoxifene nawo asetshenziselwa ukuvimbela i-osteoporosis (isimo lapho amathambo eba mncane futhi abe buthakathaka futhi aphule kalula) kwabesifazane asebedlule esikhathini. I-Estrogen isesigabeni semithi ebizwa ngamahomoni kanti i-bazedoxifene isesigabeni semithi ebizwa nge-estrogen agonist – antagonists. I-Estrogen isebenza ngokushintsha i-estrogen evame ukukhiqizwa ngumzimba. I-Bazedoxifene isetshenziselwa ukuvimba isenzo se-estrogen kulwelwesi lwesibeletho, kunciphisa ubungozi bokukhula okungaholela kumdlavuza.

Inhlanganisela ye-Estrogen ne-bazedoxifene iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa nokudla noma ngaphandle kokudla kanye ngosuku. Thatha i-estrogen ne-bazedoxifene ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-estrogen ne-bazedoxifene njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya yonke ithebhulethi; ungawahlukanisi, ungawahlafune noma uwagxoze.

I-Estrogen ne-bazedoxifene kungasiza ukulawula izimpawu zakho uma nje uqhubeka nokuphuza umuthi. Ungayeki ukuthatha i-estrogen ne-bazedoxifene ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-estrogen ne-bazedoxifene,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergen ku-estrogen (emithini eminingi yokushintsha ama-hormone nemithi yokulawula ukuzalwa), i-bazedoxifene, noma imuphi omunye umuthi, noma iziphi izithako kumathebulethi e-estrogen kanye ne-bazedoxifene. Buza usokhemisi wakho noma hlola imininingwane yomkhiqizi ngesiguli ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela nemishanguzo ongayinikiwe, amavithamini, nezithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Qiniseka ukuthi uyayisho imithi ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nanoma yikuphi okulandelayo: ama-antibiotic athile ahlanganisa i-clarithromycin (Biaxin) ne-erythromycin (E.E.S, E-Mycin); imishanguzo ethize yokubulala izinhlungu kubandakanya i-itraconazole (Sporanox) ne-ketoconazole (Nizoral); nemithi ethile yokuquleka okubandakanya i-carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, ne-phenytoin (Dilantin); imithi ye-thyroid esikhundleni semithi; i-rifampin (i-Rifadin, i-Rimactane, e-Rifamate), ne-ritonavir (i-Norvir, e-Kaletra). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi iSt John's wort.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso. Udokotela wakho angakutshela ukuthi ungathathi i-estrogen ne-bazedoxifene.
• Tshela udokotela wakho uma uneminyaka engaphezu kwengama-75 ubudala futhi uma uke waba ne-jaundice (isimo esibangela ukuphuzi kwesikhumba noma kwamehlo) ngesikhathi sokukhulelwa noma ngesikhathi sokwelashwa kwakho ngomkhiqizo we-estrogen. Phinda utshele udokotela wakho uma uke waba nesifuba somoya, isifo sikashukela, isithuthwane, i-migraine ikhanda elibuhlungu porphyria (isimo lapho izinto ezingavamile zakha khona egazini futhi zidale izinkinga ngesikhumba noma ohlelweni lwezinzwa), ifa angioedema (isimo esizuzwe njengefa esidala iziqephu. ukuvuvukala ezandleni, ezinyaweni, ebusweni, emoyeni, noma emathunjini), i-hypoparathyroidism (isimo lapho umzimba ungakhiqizi khona i-hormone eyanele ye-parathyroid), noma isifo sezinso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-estrogen ne-bazedoxifene, shayela udokotela wakho ngokushesha. I-Estrogen ne-bazedoxifene zingalimaza umbungu.
• uma uthatha i-estrogen ukuvimbela i-osteoporosis, khuluma nodokotela wakho ngezinye izindlela zokuvimbela lesi sifo njengokuvivinya umzimba nokuthatha izithako ze-vitamin D kanye / noma ze-calcium.

Ungadli inani elikhulu lamagilebhisi noma uphuze ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Estrogen ne-bazedoxifene kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• isilungulela
• ubuhlungu besisu
• isifo sohudo
• ukuqina kwemisipha
• ubuhlungu bentamo
• Umphimbo obuhlungu
• isiyezi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• Amehlo aqhamukayo
• ukuvuvukala kwamehlo, ubuso, umlomo, ulimi, noma umphimbo
• ukushaqeka
• ukuphefumula kanzima noma ukugwinya

Ukuthatha i-estrogen ne-bazedoxifene kungakhuphula ubungozi bokuthi uzoba nomdlavuza wamaqanda noma isifo se-gallbladder okufanele welashwe ngokuhlinzwa. Khuluma nodokotela wakho ngezingozi zokuthatha lo muthi.

I-Estrogen ne-bazedoxifene kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esikhwameni se-foil kanye ne-blister pack ingene, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Uma uthola izikhwama zemithi ezingaphezulu kwesisodwa, ungavuli isikhwama sesibili uze usebenzise yonke imithi esikhwameni sokuqala. Maka usuku ovula ngalo isikhwama se-foil bese ulahla noma yimiphi imithi engasetshenziswanga esikhwameni ngemuva kwezinsuku ezingama-60 uyivulile. Ungawasusi amaphilisi ku-blister pack uze ulungele ukuwathatha. Ungagcini amaphilisi ebhokisini lamaphilisi noma kumhleli wamaphilisi.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ukuhlanza
• isisa sebele
• isiyezi
• ubuhlungu besisu
• ukukhathala
• ukopha esithweni sangasese

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha i-estrogen ne-bazedoxifene.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Duavee^®