I-Apomorphine Sublingual

-Delile

• Ukuze usebenzise ifilimu elingaphansi kwe-apomorphine, landela lezi zinyathelo:
• Ngaphambi kokusebenzisa i-apomorphine,
• Izilimi ezingaphansi kwe-Apomorphine zingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwezindlela ezithile, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Apomorphine sublingual isetshenziselwa ukwelapha iziqephu ze- `` off '' (izikhathi zobunzima bokuhamba, ukuhamba, nokukhuluma okungenzeka njengoba umuthi uphela noma ungahleliwe) kubantu abanesifo esithuthukile seParkinson's (PD; ukuphazamiseka kwesistimu yezinzwa okubanga ubunzima ngokunyakaza, ukulawula imisipha, nokulinganisela). I-Apomorphine isekilasini lemithi ebizwa ngama-dopamine agonists. Isebenza ngokusebenza esikhundleni se-dopamine, into yemvelo ekhiqizwa ebuchosheni edingekayo ukulawula ukunyakaza.

I-Apomorphine iza njengefilimu engezansi eyothathwa ngaphansi kolimi. I-Apomorphine sublingual ivame ukusetshenziswa lapho idingeka, ngokuyalelwa ngudokotela wakho. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-apomorphine sublingual ncamashi njengoba iqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Ungasebenzisi umthamo wesibili we-apomorphine sublingual ekwelapheni isiqephu esifanayo "sokucisha". Linda okungenani amahora ama-2 phakathi kwemithamo futhi ungasebenzisi imithamo engaphezu kuka-5 ngosuku.

Udokotela wakho uzokunikeza omunye umuthi obizwa nge-trimethobenzamide (Tigan) ozowuthatha lapho uqala ukusebenzisa i-apomorphine sublingual. Le mithi izosiza ukunciphisa amathuba akho okuthuthukisa isicanucanu nokuhlanza ngenkathi usebenzisa i-apomorphine, ikakhulukazi ngenkathi kuqala ukwelashwa. Udokotela wakho mhlawumbe uzokutshela ukuthi uqale ukuthatha i-trimethobenzamide ezinsukwini ezi-3 ngaphambi kokuba uqale ukusebenzisa i-apomorphine, futhi uqhubeke nokuyiphuza izinyanga ezi-2. Kufanele wazi ukuthi ukuthatha i-trimethobenzamide kanye ne-apomorphine kungakhuphula ubungozi bokuzela, isiyezi nokuwa. Kodwa-ke, ungayeki ukuthatha i-trimethobenzamide ngaphandle kokukhuluma nodokotela wakho kuqala.

Uzothola umthamo wakho wokuqala we-apomorphine ehhovisi lezokwelapha lapho udokotela wakho angakwazi khona ukuqapha isimo sakho eduze ukuze anqume umthamo wakho. Ngemuva kwalokho, udokotela wakho uzokutshela ukuthi usebenzise i-apomorphine sublingual ekhaya futhi ubheke imiphumela emibi.

Ukuze usebenzise ifilimu elingaphansi kwe-apomorphine, landela lezi zinyathelo:

1. Phuza amanzi ukuthambisa umlomo wakho.
2. Vula isikhwama usebenzisa amathebhu ephiko. Qiniseka ukuthi ubeka iminwe yakho ngqo kumachashazi aphakanyisiwe kuthebhu ngayinye yephiko. Donsa kahle amathebhu ephiko ukuze uvule isikhwama. Ungavuli iphakethe le-foil uze ulungele ukusebenzisa umuthi. Musa ukusika noma ukudabula ifilimu.
3. Bamba ifilimu elincane lama-apomorphine phakathi kweminwe yakho ngamaphethelo angaphandle bese ususa yonke ifilimu esikhwameni. Sebenzisa i-apomorphine sublingual film ephelele. Uma lephukile, lilahle bese usebenzisa umthamo omusha.
4. Faka yonke ifilimu yolimi olungaphansi kolimi lwakho emuva kakhulu ngaphansi kolimi lwakho ngangokunokwenzeka. Vala umlomo wakho.
5. Shiya ifilimu isendaweni ize inyibilike ngokuphelele. Kungathatha imizuzu emithathu ukuthi ifilimu incibilike. Ungayihlafune noma uyigwinye ifilimu. Ungagwinyi amathe akho noma ukhulume njengoba ifilimu incibilika.
6. Vula umlomo wakho ukuze ubone ukuthi ifilimu ichithwe ngokuphelele.
7. Ngemuva kokuthi ifilimu ekhulunywa ngaphansi kwezilimi ezimbili isichithakale ngokuphelele, ungaphinda ugwinye.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-apomorphine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-apomorphine, noma imiphi eminye imishanguzo, ama-sulfite, noma ezinye izithako kulimi olungaphansi lwama-apomorphine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-alosetron (Lotronex), i-dolasetron (i-Anzemet), i-granisetron (i-Sancuso), i-ondansetron (i-Zofran), noma i-palonosetron (i-Aloxi). Udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi i-apomorphine uma uthatha omunye wale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-azithromycin (Zithromax), i-chlorpromazine, i-chloroquine, i-ciprofloxacin (i-Cipro), i-haloperidol (i-Haldol); imithi yokwelapha umfutho wegazi ophakeme; i-methadone (i-Dolophine); i-metoclopramide (Reglan); iprochlorperazine (Compro); i-promethazine; amaphilisi okulala; thiothixene; noma izinto zokunciphisa umzimba. Phinda utshele udokotela noma usokhemisi wakho uma uthatha ama-nitrate afana ne-isosorbide dinitrate (Isordil, e-Bidil), isosorbide mononitrate (Monoket), noma i-nitroglycerin (i-Nitro-Dur, i-Nitrostat, amanye) eza njengamaphilisi, amagama amancane (ngaphansi kolimi) amaphilisi, izifutho, amabala, iziqhumane, namafutha okugcoba.Buza udokotela noma usokhemisi wakho uma ungaqiniseki ukuthi ikhona yini imithi yakho equkethe ama-nitrate. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• kufanele wazi ukuthi uma usebenzisa i-nitroglycerin ngaphansi kolimi lwakho ngenkathi usebenzisa i-apomorphine sublingual, umfutho wegazi lakho ungancipha futhi ubangele isiyezi. Ngemuva kokusebenzisa i-apomorphine sublingual, kufanele ulale ngaphambi nangemva kokusebenzisa i-nitroglycerin.
• Tshela udokotela wakho uma uphuza utshwala noma uma uke waba nesikhathi sokuphumula se-QT (inkinga engavamile yenhliziyo engadala ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ukufa okungazelelwe), ukuphelelwa amandla, amazinga aphansi we-potassium noma i-magnesium egazini, ukushaya kwenhliziyo okuhamba kancane noma okungajwayelekile, umfutho ophansi wegazi, ukuphazamiseka kokulala, isifo sohlangothi, ukushaywa unhlangothi, noma ezinye izinkinga zobuchopho, isifuba somoya, ukunyakaza nokuwa okungazelele okungazelelwe nokugula, ukugula kwengqondo, noma inhliziyo, isifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-apomorphine sublingual, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-apomorhine sublingual.
• kufanele wazi ukuthi i-apomorphine ingakwenza ukozele. Ungashayeli imoto, sebenzisa imishini, noma wenze noma yini engakubeka engcupheni yokulimala uze wazi ukuthi lo muthi ukuthinta kanjani.
• akufanele uphuze utshwala ngenkathi usebenzisa i-apomorphine. Utshwala bungenza imiphumela emibi evela ku-apomorphine ibe yimbi kakhulu.
• kufanele wazi ukuthi i-apomorphine ingadala isiyezi, ikhanda elikhanyayo, isicanucanu, ukujuluka, nokuquleka lapho uvuka ngokushesha okukhulu endaweni yokulala noma yokuhlala. Lokhu kuvame kakhulu lapho uqala ukusebenzisa i-apomorphine noma ulandela ukwanda komthamo. Ukugwema le nkinga, vuka embhedeni noma uvuke endaweni yokuhlala kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
• kufanele wazi ukuthi abanye abantu abathathe imishanguzo efana ne-apomorphine baba nezinkinga zokugembula noma ezinye izifiso ezinamandla noma izindlela zokuziphatha ezazicindezela noma zingajwayelekile kubo, njengokunyuka kwezifiso zocansi noma isimilo. Akukho mininingwane eyanele yokutshela ukuthi ngabe abantu baba nezinkinga yini ngenxa yokuthi bathathe umuthi noma ngenxa yezinye izizathu. Shayela udokotela wakho uma unesifiso sokugembula okunzima ukusilawula, unezikhalazo ezinkulu, noma awukwazi ukulawula ukuziphatha kwakho. Tshela amalungu omndeni wakho ngale ngozi ukuze bakwazi ukubiza udokotela noma ngabe awuboni ukuthi ukugembula kwakho noma yiziphi ezinye izifiso ezinamandla noma ukuziphatha okungajwayelekile kube yinkinga.
• kufanele wazi ukuthi ungazuma ngokuzumayo ngesikhathi semisebenzi yakho ejwayelekile yansuku zonke ngenkathi usebenzisa i-apomorphine sublingual. Ungahle ungazeli ukozela ngaphambi kokulala. Uma uvele ulale ngokuzumayo ngenkathi wenza umsebenzi wansuku zonke njengokudla, ukukhuluma, noma ukubukela ithelevishini, shayela udokotela wakho. Ungashayeli imoto noma usebenzise imishini uze ukhulume nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Lo muthi uvame ukusetshenziswa lapho kudingeka.

Izilimi ezingaphansi kwe-Apomorphine zingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuhlanza
• umlomo owomile
• ikhanda
• ikhala eligijimayo
• ukukhathala
• ububomvu bomlomo, izilonda, ukoma, ukuvuvukala, noma ubuhlungu
• ubuhlungu ngokugwinya

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwezindlela ezithile, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka; isifuba; ukulunywa; ukuvuvukala kobuso, umphimbo, ulimi, noma izindebe; ukuqhuma; ukuqina komphimbo; noma ukuphefumula kanzima noma ukugwinya
• Iwela phansi
• ukubona izinto ezingekho (ukubona izinto noma ukuzwa amazwi angekho), isimilo esinolaka, ukukhathazeka, ukuzizwa njengabantu abamelene nawe, noma imicabango engahlelekile
• umkhuhlane, imisipha eqinile, ukushintsha kokuphefumula noma ukushaya kwenhliziyo, noma ukudideka
• ukuphefumula, ukushaya kwenhliziyo okusheshayo, ubuhlungu besifuba, noma isiyezi
• ukwakhiwa okubuhlungu okungapheli

Ezinye izilwane zaselabhorethri ezazinikezwa i-apomorphine njengomjovo zaba nesifo samehlo. Akwaziwa ukuthi ngabe ukukhuluma ngezilimi ezincane kwe-apomorphine kuyayandisa yini ingozi yesifo samehlo kubantu. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi.

Izilimi ezingaphansi kwe-Apomorphine zingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Kynmobi^®