I-Febrile neutropenia: iyini, izimbangela kanye nokwelashwa

-Delile

• Izimbangela ze-febrile neutropenia
• Injani impatho

I-Febrile neutropenia ingachazwa njengokuncipha kwenani lama-neutrophils, okutholwa ekuhlolweni kwegazi ngaphansi kuka-500 / µL, okuhambisana nomkhuhlane ngaphezulu noma okulingana no-38ºC ngehora elilodwa. Lesi simo sivame kakhulu kwiziguli ezinomdlavuza ngemuva kwe-chemotherapy futhi singaholela emiphumeleni nasezinkingeni ekwelashweni uma singelashwa ngokushesha.

Ama-neutrophils amangqamuzana egazi amakhulu abhekele ukuvikela nokulwa nezifo, inani elijwayelekile elibhekwa phakathi kuka-1600 no-8000 / µL, elingase lihluke ngokuya kwelabhorethri. Lapho inani lama-neutrophils lilingana noma likhulu kuno-500 / µL, kubhekwa i-neutropenia enamandla, ukuze umuntu athinteke kalula ekungenweni yizifo ngama-microorganisms ahlala emzimbeni ngokwemvelo.

Izimbangela ze-febrile neutropenia

I-Febrile neutropenia iyinkinga eyenzeka njalo ezigulini ezinomdlavuza ezelashwa ngamakhemikhali, njengenye yezimbangela ezinkulu zokufa kulezi ziguli, ngoba ukwehla kwama-neutrophils kwandisa ubungozi bomuntu bokuthola izifo ezinzima.

Ngaphezu kokwelashwa ngamakhemikhali, i-febrile neutropenia ingenzeka ngenxa yezifo ezingalapheki ezibangelwa isikhunta, amabhaktheriya namagciwane, ikakhulukazi igciwane le-Epstein-Barr ne-hepatitis. Funda ngezinye izimbangela ze-neutropenia.

Injani impatho

Ukwelashwa kwe-febrile neutropenia kuyehluka ngokuya ngobukhulu. Iziguli ezikhonjwe njengezine-febrile neutropenia enamandla, lapho inani lama-neutrophils lingaphansi noma lilingana no-200 / µL, imvamisa liphathwa ngokusetshenziswa kwama-antibiotic ekilasi lama-beta-lactams, i-cephalosporins yesizukulwane sesine noma i-carbapenems. Ngaphezu kwalokho, esimweni sesiguli esingazinzile emtholampilo noma okusolwa ukuthi sine-virus engazweli, kunganconywa ukuthi kusetshenziswe elinye i-antibiotic ukulwa nalesi sifo.

Ezimweni ze-febrile neutropenia enobungozi obuphansi, isiguli sivame ukubhekwa, futhi ukubalwa kwegazi okuphelele kufanele kwenziwe ngezikhathi ezithile ukuhlola amazinga ama-neutrophils. Ngaphezu kwalokho, uma ukutheleleka kwefungal noma ibhaktheriya kuqinisekisiwe, ukusetshenziswa kwama-antimicrobial, kungaba ama-antibiotic noma ama-antifungal, kunganconywa ngudokotela ngokuya nge-ejenti ebhekene nokutheleleka.

Lapho i-febrile neutropenia ivela ngemuva kwe-chemotherapy, kunconywa ukuthi ukwelashwa kwama-antibiotic kuqalwe ngokushesha okukhulu ngaphakathi kwehora elilodwa ngemuva kokubheka umkhuhlane.