I-Pamidronato

-Delile

• Izinkomba zePamidronate
• Intengo yePamidronato
• Imiphumela emibi ye-Pamidronate
• Ukungafani kwePamidronate
• Ungayisebenzisa kanjani i-Pamidronate

I-Pamidronate yinto esebenzayo kumuthi olwa ne-hypercalcemic owaziwa ngokuthengisa njenge-Aredia.

Lesi sidakamizwa sokusetshenziswa komjovo sikhonjisiwe ngesifo sikaPaget, i-osteolysis ngoba sivimbela ukubuyiselwa kwamathambo ngezindlela eziningana, ukunciphisa izimpawu zezifo.

Izinkomba zePamidronate

Isifo samathambo sikaPaget; i-hypercalcemia (ehlotshaniswa neoplasia); i-osteolysis (ebangelwa isimila sebele noma i-myeloma).

Intengo yePamidronato

Intengo yomuthi ayitholakalanga.

Imiphumela emibi ye-Pamidronate

Ukwehla kwe-potassium yegazi; kwehle phosphates egazini; ukuqubuka kwesikhumba; ukuqina; ubuhlungu; ukushaya ngonyawo; ukuvuvukala; ukuvuvukala komthambo; imfiva ephansi yesikhashana.

Ezimweni zezifo zikaPaget: umfutho wegazi owandisiwe; ubuhlungu bamathambo; ikhanda; ubuhlungu obuhlangene.

Ezimweni ze-osteolysis: i-anemia; ukulahlekelwa ukudla; ukukhathala; ukuphefumula kanzima ukugaya; isisu esibuhlungu; ubuhlungu obuhlangene; ukukhwehlela; ikhanda.

Ukungafani kwePamidronate

Ingozi Yokukhulelwa C; ukuncelisa: iziguli ezinokungezwani komzimba nama-bisphosphonates; Ukuzwela ngokweqile kunoma yiziphi izingxenye zefomula.

Ungayisebenzisa kanjani i-Pamidronate

Ukusetshenziswa ngomjovo

Abantu abadala

• I-Hypercalcemia: 60 mg enikezwe ngaphezu kwamahora ama-4 kuye kwangama-24 (i-hypercalcemia enamandla kakhulu - i-serum calcium elungisiwe engaphezulu kuka-13.5 mg / dL - ingadinga u-90 mg ofakwe ngaphezulu kwamahora angama-24)
• Iziguli ezinokukhubazeka kwezinso noma ezine-hypercalcemia emnene: I-60 mg ilawulwa ngaphezulu kwamahora ama-4 kuye kwangama-24.

Amakhanda phezulu: uma i-hypercalcemia iphinda ibuya, ukwelashwa okusha kungabhekwa inqobo nje uma sekudlule okungenani izinsuku eziyi-7.

• Isifo sikaPaget sethambo: Umthamo ophelele ka-90 kuya ku-180 mg ngesikhathi sokwelashwa ngasinye; umthamo ophelele ungalawulwa ku-30 ​​mg nsuku zonke ngezinsuku ezi-3 ezilandelanayo noma i-30 mg kanye ngesonto amasonto ayisithupha. Izinga lokuphatha lihlala liyi-15 mg ngehora.
• I-osteolysis ebangelwa isimila (kumdlavuza webele): I-90 mg ilawulwa ngaphezulu kwamahora ama-2, njalo emavikini ama-3 noma ama-4; (e-myeloma): 90 mg ilawulwa ngaphezulu kwamahora ama-2, kanye ngenyanga.