Ngabe Ukwelashwa Okulethwe Ngompompi Ikusasa Lokwelashwa Kwezifo zikaParkinson?

-Delile

• Isebenza kanjani ukwelashwa okuhanjiswa ngempompo
• Ukusebenza kokwelapha okwenziwe ngempompo
• Izingozi ezingaba khona
• Umbono

Iphupho lesikhathi eside kwabaningi abaphila nesifo sikaParkinson bekungukunciphisa inani lamaphilisi ansuku zonke adingekayo ukuphatha izimpawu. Uma inqubo yakho yansuku zonke yamaphilisi ingagcwalisa izandla zakho, mhlawumbe uyalandisa. Lapho lesi sifo siqhubeka, kuba nzima ukuphatha izimpawu, futhi ugcina usudinga imishanguzo eyengeziwe noma imithamo ejwayelekile, noma kokubili.

Ukwelashwa okulethwa ngepompo ukwelashwa kwakamuva okuvunyelwe yi-U.S. Food and Drug Administration (FDA) ngoJanuwari 2015. Ivumela ukuthi imithi ithunyelwe ngqo njengejeli emathunjini akho amancane. Le ndlela yenza sikwazi ukunciphisa kakhulu inani lamaphilisi adingekayo futhi sithuthukise ukukhululeka kwezimpawu.

Funda ukuze ufunde kabanzi mayelana nokuthi ukwelashwa okuhanjiswa ngempompo kusebenza kanjani nokuthi kungaba kanjani yintuthuko enkulu elandelayo ekwelashweni kukaParkinson.

Isebenza kanjani ukwelashwa okuhanjiswa ngempompo

Ukulethwa kwepompo kusebenzisa umuthi ofanayo ovame ukubekwa kwifomu lephilisi, inhlanganisela ye-levodopa ne-carbidopa. Uhlobo lwamanje olwamukelwe yi-FDA lokulethwa kwepompo yi-gel ebizwa nge-Duopa.

Izimpawu zeParkinson's, njengokuthuthumela, inkinga yokuhamba, nokuqina, zidalwa ukuthi ubuchopho bakho abunayo i-dopamine eyanele, ikhemikhali ubuchopho obuvamile ukuba nalo. Ngoba ubuchopho bakho abunakunikwa i-dopamine eyengeziwe ngqo, i-levodopa isebenza ukwengeza i-dopamine eyengeziwe ngenqubo yemvelo yobuchopho. Ingqondo yakho iguqula i-levodopa ibe yi-dopamine lapho idlula.

ICarbidopa ixutshwe nelevodopa ukuvimba umzimba wakho ukuthi ungaphuli i-levodopa ngokushesha okukhulu. Kuyasiza futhi ukuvimbela isicanucanu, umthelela oseceleni obangelwa yi-levodopa.

Ukuze usebenzise le ndlela yokwelashwa, udokotela wakho udinga ukwenza inqubo encane yokuhlinza: Bazofaka ithubhu ngaphakathi komzimba wakho elifinyelela engxenyeni yamathumbu akho amancane esiswini sakho. Ishubhu ixhuma esikhwameni esingaphandle komzimba wakho, esingafihlwa ngaphansi kwehembe lakho. Iphampu neziqukathi ezincane eziphethe umuthi wejeli, okuthiwa amakhasethi, zingena ngaphakathi kwesikhwama. Ikhasethi ngalinye linejeli engabiza amahora angu-16 iphampu eliletha emathunjini akho amancane usuku lonke.

Iphampu libe selilungiselelwa ngokwamanani ukukhipha umuthi ngamanani afanele. Konke okuzodingeka ukwenze ukushintsha ikhasethi kanye noma kabili ngosuku.

Uma usuphethe ipompo, kuzodingeka ukuthi ubhekwe njalo ngudokotela wakho. Uzodinga futhi ukunaka kakhulu indawo yesisu sakho lapho kuxhuma khona ithubhu. Uchwepheshe oqeqeshiwe uzodinga ukuhlela iphampu.

Ukusebenza kokwelapha okwenziwe ngempompo

Ukuhlanganiswa kwe-levodopa ne-carbidopa kubhekwa njengomuthi osebenza kahle kakhulu wezimpawu zika-Parkinson ezitholakalayo namuhla. Ukwelashwa okulethwa ngepompo, ngokungafani namaphilisi, kuyakwazi ukunikeza ukugeleza okungapheli kwemithi. Ngamaphilisi, umuthi uthatha isikhathi ukungena emzimbeni wakho, bese kuthi lapho usuphelile kufanele uthathe omunye umthamo.Kwabanye abantu abaneParkinson ethuthuke kakhulu, umthelela wamaphilisi uyaguquguquka, futhi kuba nzima ukuqagela ukuthi aqala ukusebenza nini futhi isikhathi esingakanani.

Ucwaningo lukhombisile ukuthi ukwelashwa okuhanjiswa ngempompo kuyasebenza. Kuthathwa njengenketho enhle kubantu abasezigabeni zakamuva zikaParkinson abangase bangabe besathola ukukhululeka kwezimpawu ezifanayo ekuphuzeni amaphilisi.

Isizathu esisodwa salokhu ukuthi njengoba iParkinson iqhubeka, iguqula indlela isisu sakho esisebenza ngayo. Ukugaya kunganciphisa futhi kungalindelekile. Lokhu kungathinta ukuthi umuthi wakho usebenza kanjani lapho uphuza amaphilisi, ngoba amaphilisi adinga ukuhamba ohlelweni lwakho lokugaya ukudla. Ukuletha umuthi ngqo emathunjini akho amancane kuwungenisa emzimbeni wakho ngokushesha nangokungaguquguquki.

Khumbula ukuthi noma ngabe iphampu likusebenzela kahle, kusengenzeka ukuthi ungadinga ukuphuza iphilisi kusihlwa.

Izingozi ezingaba khona

Noma iyiphi inqubo yokuhlinzwa inezingozi ezingaba khona. Okwepompo, lokhu kungafaka:

• ukutheleleka kuyakhula lapho ithubhu ingena khona emzimbeni wakho
• ukuvinjelwa okwenzeka kushubhu
• ishubhu liyawa
• ukuvuza okuthuthukayo kushubhu

Ukuze kuvinjelwe ukutheleleka kanye nezinkinga, abanye abantu bangadinga umbheki wokuqapha ithubhu.

Umbono

Ukwelashwa okulethwa ngamaphampu kusenemikhawulo ethile, njengoba kukusha uma kuqhathaniswa. Kungahle kungabi yisixazululo esifanelekile kuzo zonke iziguli: Inqubo encane yokuhlinza ukubeka ithubhu iyabandakanyeka, futhi ithubhu idinga ukuqashwa ngokucophelela kanye endaweni. Kodwa-ke, kukhombisa ukuthembisa ekusizeni abanye abantu behlise kakhulu imithamo yabo yamaphilisi ansuku zonke ngenkathi ibanikeza izikhala ezinde phakathi kwezimpawu.

Ikusasa lokwelashwa kukaParkinson alikabhalwa. Njengoba abacwaningi befunda kabanzi ngeParkinson's nokuthi lesi sifo sisebenza kanjani ebuchosheni, ithemba labo ukuthola izindlela zokwelapha ezingagcini nje ngokuqeda izimpawu, kodwa futhi ezisiza ukuguqula lesi sifo uqobo.