Craniopharyngioma

I-craniopharyngioma iyisigaxa esingenomdlavuza (esinobuthi) esikhula ngaphansi kobuchopho eduze kwendlala yamapayipi.

Imbangela ngqo yalesi sifo ayikaziwa.

Lesi simila sithinta kakhulu izingane ezineminyaka ephakathi kwemihlanu kuya kwengu-10 ubudala. Abantu abadala kwesinye isikhathi bangathinteka. Abafana namantombazane nabo banamathuba afanayo okuba nalesi sifo.

I-Craniopharyngioma idala izimpawu ngo:

• Ukucindezela okwandayo ebuchosheni, imvamisa kusuka ku-hydrocephalus
• Ukuphazamisa ukukhiqizwa kwamahomoni ngendlala ye-pituitary
• Ingcindezi noma ukulimala kwe-optic nerve

Ukucindezela okwengeziwe ebuchosheni kungadala:

• Ubuhlungu bekhanda
• Isicanucanu
• Ukuhlanza (ikakhulukazi ekuseni)

Ukulimala kwe-pituitary gland kubanga ukungalingani kwe-hormone okungaholela ekomeni ngokweqile nasekuchameni, nokukhula kancane.

Lapho i-nerve optic ilinyazwa isimila, kuba nezinkinga zombono. Lokhu kukhubazeka kuvame ukuhlala unomphela. Bangase babe babi kakhulu ngemuva kokuhlinzwa ukuze kususwe isimila.

Izinkinga zokuziphatha nezokufunda kungenzeka zibe khona.

Umhlinzeki wakho wokunakekelwa kwezempilo uzokwenza ukuhlolwa komzimba. Kuzokwenziwa izivivinyo zokubheka isimila. Lokhu kungafaka:

• Ukuhlolwa kwegazi ukukala amazinga ama-hormone
• I-CT scan noma i-MRI scan yobuchopho
• Ukuhlolwa kwesistimu yezinzwa

Inhloso yokwelashwa ukukhulula izimpawu. Imvamisa, ukuhlinzwa kube ukwelashwa okuyinhloko kwe-craniopharyngioma. Kodwa-ke, ukwelashwa ngemisebe esikhundleni sokuhlinzwa noma kanye nokuhlinzwa okuncane kungaba yindlela engcono kakhulu kwabanye abantu.

Ezingqungqutheleni ezingenakususwa ngokuphelele ngokuhlinzwa kuphela, kusetshenziswa ukwelashwa ngemisebe.Uma isimila sinokubukeka okujwayelekile ku-CT scan, i-biopsy kungenzeka ingadingeki uma kuhlelwa ukwelashwa ngemisebe kuphela.

I-radiosurgery ye-stereotactic yenziwa kwezinye izikhungo zezokwelapha.

Lesi simila siphathwa kahle esikhungweni esinolwazi lokwelapha ama-craniopharyngiomas.

Ngokuvamile, umbono muhle. Kukhona amathuba okuphulukiswa angama-80% kuya kuma-90% uma isimila singasuswa ngokuphelele ngokuhlinzwa noma siphathwe ngemithamo ephezulu yemisebe. Uma isimila sibuya, sivame ukubuya kungakapheli iminyaka emibili yokuqala ngemuva kokuhlinzwa.

I-Outlook incike ezintweni eziningana, kufaka phakathi:

• Ukuthi isimila singasuswa ngokuphelele yini
• Yiziphi izinkinga zesistimu yezinzwa nokungalingani kwamahomoni okubangelwa isimila nokwelashwa

Iningi lezinkinga ezinama-hormone nokubona akubi ngcono ngokwelashwa. Kwesinye isikhathi, ukwelashwa kungaze kubenze babi kakhulu.

Kungaba nezinkinga zesikhathi eside zehomoni, umbono, kanye nohlelo lwezinzwa ngemuva kokuphathwa kwe-craniopharyngioma.

Lapho isimila singasuswanga ngokuphelele, isimo singabuya.

Shayela umhlinzeki wakho ngezimpawu ezilandelayo:

• Ubuhlungu bekhanda, isicanucanu, ukuhlanza, noma izinkinga zebhalansi (izimpawu zokucindezela okwandayo ebuchosheni)
• Ukwanda ukoma nokuchama
• Ukukhula kabi kwengane
• Umbono uyashintsha

• Izindlala ze-Endocrine

I-Styne DM. I-Physiology nokuphazamiseka kokuthomba. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 26.

USuh JH, Chao ST, uMurphy ES, amaRecinos PF. Izicubu zepituitary kanye ne-craniopharyngiomas. Ku: Tepper JE, Foote RL, Michalski JM, eds. I-Gunderson & Tepper's Clinical Radiation Oncology. Umhlaka 5. IPhiladelphia, PA: Elsevier; 2021: isahluko 34.

UZaky W, Ater JL, Khatua S. Izicubu zobuchopho ebuntwaneni. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 524.