Isifo seHemoglobin C

Isifo seHemoglobin C yisifo segazi esidluliselwa emindenini. Kuholela ohlotsheni lwe-anemia, olwenzeka lapho amangqamuzana abomvu egazi ehla ngaphambi kwesikhathi esijwayelekile.

IHemoglobin C uhlobo olungajwayelekile lwe-hemoglobin, iphrotheni emangqamuzaneni abomvu egazi athwala umoya-mpilo. Luhlobo lwe-hemoglobinopathy. Lesi sifo sidalwa inkinga yesakhi sofuzo esibizwa nge-beta globin.

Lesi sifo sivame ukwenzeka kubantu base-Afrika baseMelika. Kungenzeka ukuthi ube nesifo se-hemoglobin C uma othile emndenini wakho enaso.

Iningi labantu alinazo izimpawu. Kwezinye izimo, i-jaundice ingenzeka. Abanye abantu bangaba namatshe enyongo adinga ukwelashwa.

Ukuhlolwa komzimba kungakhombisa ubende obukhulisiwe.

Ukuhlolwa okungenziwa kufaka phakathi:

• Qedela ukubalwa kwegazi
• I-hemoglobin electrophoresis
• I-peripheral blood smear
• I-hemoglobin yegazi

Ezimweni eziningi, akukho ukwelashwa okudingekayo. Izengezo ze-Folic acid zingasiza umzimba wakho ukuthi ukhiqize amaseli abomvu ejwayelekile futhi uthuthukise izimpawu ze-anemia.

Abantu abanesifo i-hemoglobin C bangalindela ukuphila impilo ejwayelekile.

Izinkinga zingafaka:

• Ukushoda kwegazi
• Isifo se-gallbladder
• Ukwandiswa kobende

Shayela umhlinzeki wakho wezokunakekelwa kwezempilo uma unezimpawu zesifo se-hemoglobin C.

Ungahle ufune ukululekwa ngezakhi zofuzo uma usengozini enkulu yalesi simo futhi ucabanga ukuthola ingane.

I-hemoglobin emitholampilo C

• Amaseli egazi

Isifo samangqamuzana kaHoward J. Sickle namanye ama-hemoglobinopathies. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 154.

USmith-Whitley K, Kwiatkowski JL. Ama-hemoglobinopathies. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 489.

UWilson CS, uVergara-Lluri ME, uBrynes RK. Ukuhlolwa kwe-anemia, leukopenia, ne-thrombocytopenia. Ku: Jaffe ES, Arber DA, Campo E, Harris NL, Quintanilla-Martinez L, abahleli. I-Hematopathology. Okwesibili. IPhiladelphia, PA: Elsevier; I-2017: isahluko 11.