Inkinga ye-hemolytic

Inkinga ye-hemolytic yenzeka lapho inani elikhulu lamangqamuzana abomvu egazi libhujiswa esikhathini esifushane. Ukulahleka kwamangqamuzana abomvu egazi kwenzeka ngokushesha okukhulu kunokuthi umzimba ungakhiqiza amangqamuzana egazi abomvu amasha.

Ngesikhathi senkinga ye-hemolytic, umzimba awukwazi ukwenza amangqamuzana egazi abomvu anele ukuthatha indawo yalezo ezibhujisiwe. Lokhu kubangela i-anemia enamandla futhi evame ukuba yimbi.

Ingxenye yamaseli abomvu egazi ethwala umoya-mpilo (i-hemoglobin) ikhishelwa egazini. Lokhu kungaholela ekulimaleni kwezinso.

Izimbangela ze-hemolysis zifaka:

• Ukuntuleka kwamaprotheni athile ngaphakathi kwamaseli abomvu egazi
• Izifo ezizimele
• Izifo ezithile
• Amaphutha kuma-molecule e-hemoglobin ngaphakathi kwamaseli abomvu egazi
• Amaphutha amaprotheni akha uhlaka lwangaphakathi lwamaseli abomvu egazi
• Imiphumela emibi yemithi ethile
• Ukusabela ekumpontshelweni igazi

Shayela umhlinzeki wakho wezokunakekelwa kwezempilo uma une:

• Izimpawu ze-anemia, kufaka phakathi isikhumba esiphaphathekile noma ukukhathala, ikakhulukazi uma lezi zimpawu ziba zimbi kakhulu
• Umchamo obomvu, obomvu-nsundu, noma onsundu (umbala wetiye)

Ukwelashwa okuphuthumayo kungadingeka. Lokhu kungabandakanya ukuhlala esibhedlela, umoya-mpilo, ukumpontshelwa igazi nezinye izindlela zokwelashwa.

Lapho isimo sakho sizinzile, umhlinzeki wakho uzokwenza ukuhlolwa komzimba abuze ngomlando wakho wezokwelapha nezimpawu. Ukuhlolwa komzimba kungakhombisa ukuvuvukala kobende (splenomegaly).

Ukuhlolwa okungenziwa kufaka phakathi:

• Iphaneli lekhemistri yegazi
• Qedela ukubalwa kwegazi (CBC)
• Ukuhlolwa kwama-Coombs
• I-Haptoglobin
• I-Lactate dehydrogenase

Ukwelashwa kuya ngesizathu se-hemolysis.

I-hemolysis - ebukhali

IGallagher PG. Ama-anemia we-hemolytic: ulwelwesi lwegazi elibomvu nokukhubazeka komzimba. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 152.