Ukuhlolwa kwegazi kweBilirubin

Ukuhlolwa kwegazi kwe-bilirubin kukala izinga le-bilirubin egazini. I-Bilirubin i-pigment ephuzi etholakala ku-bile, uketshezi olwenziwe isibindi.

I-Bilirubin nayo ingalinganiswa ngokuhlolwa komchamo.

Kudingeka isampula yegazi.

Akufanele udle noma uphuze okungenani amahora amane ngaphambi kokuhlolwa. Umhlinzeki wakho wezokunakekelwa kwempilo angakuyalela ukuthi uyeke ukuthatha imithi ethinta ukuhlolwa.

Izidakamizwa eziningi zingashintsha izinga le-bilirubin egazini lakho. Qiniseka ukuthi umhlinzeki wakho uyazi ukuthi imiphi imithi oyiphuzayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Inani elincane lamangqamuzana egazi abomvu amadala lishintshwa ngamaseli amasha egazi nsuku zonke. I-Bilirubin isala ngemuva kokuthi la maseli amadala egazi asuswe. Isibindi sisiza ukudiliza i-bilirubin ukuze ikwazi ukususwa emzimbeni osesihlalweni.

Izinga le-bilirubin egazini lika-2.0 mg / dL lingaholela ku-jaundice. I-jaundice umbala ophuzi esikhunjeni, ulwelwesi lwamafinyila, noma emehlweni.

I-jaundice yisizathu esivame kakhulu ukuhlola izinga le-bilirubin. Ukuhlolwa kungenzeka ku-oda lapho:

• Umhlinzeki ukhathazekile nge-jaundice yengane esanda kuzalwa (iningi lezingane ezisanda kuzalwa zine-jaundice ethile)
• I-jaundice iba nezinsana ezindala, izingane kanye nabantu abadala

Ukuhlolwa kwe-bilirubin nakho kuyalwa lapho umhlinzeki esola ukuthi umuntu unenkinga yesibindi noma ye-gallbladder.

Kuyinto evamile ukuba ne-bilirubin egazini. Izinga elijwayelekile yile:

• I-Direct (ebizwa nangokuthi i-conjugated) bilirubin: ngaphansi kuka-0.3 mg / dL (ngaphansi kuka-5.1 µmol / L)
• Ingqikithi ye-bilirubin: 0.1 kuya ku-1.2 mg / dL (1.71 kuye ku-20.5 µmol / L)

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Ezinganeni ezisanda kuzalwa, izinga le-bilirubin liphakeme ezinsukwini ezimbalwa zokuqala zokuphila. Umhlinzeki wengane yakho kufanele acabangele okulandelayo lapho enquma ukuthi ngabe ileveli yebilirubin yengane yakho iphezulu kakhulu:

• Izinga belikhuphuka ngokushesha kangakanani
• Ukuthi ingane izalwe kusenesikhathi yini
• Iminyaka yengane

I-jaundice nayo ingenzeka lapho amangqamuzana egazi abomvu amaningi kunokujwayelekile ephuka. Lokhu kungabangelwa:

• Isifo segazi esibizwa nge-erythroblastosis fetalis
• Ukuphazamiseka kwamangqamuzana egazi abomvu okuthiwa i-hemolytic anemia
• Ukusabela kokumpontshelwa lapho amangqamuzana abomvu egazi anikezwe ukumpontshelwa abhujiswa amasosha omzimba womuntu

Izinkinga ezilandelayo zesibindi zingadala ne-jaundice noma izinga eliphezulu le-bilirubin:

• Ukuqubuka kwesibindi (i-cirrhosis)
• Isibindi sokuvuvukala esivuthayo (hepatitis)
• Esinye isifo sesibindi
• Ukuphazamiseka lapho i-bilirubin ingacutshungulwa ngokujwayelekile yisibindi (isifo se-Gilbert)

Izinkinga ezilandelayo nge-gallbladder noma i-bile ducts zingadala amazinga aphezulu e-bilirubin:

• Ukunciphisa okungavamile komgudu ovamile we-bile (ukuqina kwe-biliary)
• Umdlavuza wamanyikwe noma i-gallbladder
• Amatshe amatshe amade

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo iyehluka ngobukhulu kusuka komunye umuntu iye komunye futhi kusukela kolunye uhlangothi lomzimba kuye kolunye. Ukuthola isampula yegazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-Hematoma (ukuqoqa igazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ingqikithi ye-bilirubin - igazi; I-bilirubin engahlanjululwanga - igazi; I-bilirubin engaqondile - igazi; I-bilirubin ehlanganisiwe - igazi; I-bilirubin eqondile - igazi; I-jaundice - ukuhlolwa kwegazi kwe-bilirubin; Hyperbilirubinemia - ukuhlolwa kwegazi kwe-bilirubin

• I-jaundice esanda kuzalwa - ukukhipha

• Ukuhlolwa kwegazi

IChernecky CC, iBerger BJ. I-Bilirubin (isiyonke, eqondile [ehlanganisiwe] futhi engaqondile [engaqondisiwe]) - i-serum. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 196-198.

UPincus MR, u-Tierno PM, uGleeson E, uBowne WB, uBluth MH. Ukuhlolwa kokusebenza kwesibindi. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 21.

IPratt DS. I-chemistry yesibindi nokuhlolwa kokusebenza. Ku: Feldman M, Friedman LS, Brandt LJ, ama-eds. Si-leisenger ne-Fordtran's Gastrointestinal and Liver Disease: IPathophysiology / Diagnosis / Management. Umhlaka 10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 73.