Dala ukuhlolwa kwe-phosphokinase

I-Creatine phosphokinase (CPK) iyi-enzyme emzimbeni. Kutholakala ikakhulu enhliziyweni, ebuchosheni nasemisipheni yamathambo. Lo mbhalo ukhuluma ngokuhlolwa ukukala inani le-CPK egazini.

Kudingeka isampula yegazi. Lokhu kungathathwa emthanjeni. Inqubo ibizwa ngokuthi i-venipuncture.

Lokhu kuhlolwa kungaphindwa ezinsukwini ezimbili noma ezi-3 uma uyisiguli esibhedlela.

Akukho ukulungiselela okukhethekile okudingeka isikhathi esiningi.

Tshela umhlinzeki wakho wezempilo nganoma imiphi imithi oyiphuzayo. Izidakamizwa ezingakhuphula izilinganiso ze-CPK zifaka i-amphotericin B, ama-anesthetics athile, ama-statins, ama-fibrate, i-dexamethasone, i-alcohol ne-cocaine.

Ungase uzwe ubuhlungu obuncane lapho kufakwa inaliti ukuze kudonswe igazi. Abanye abantu bazizwa kuphela ukuzwa okuhlabayo noma okuhlabayo. Ngemuva kwalokho, kungahle kube nokushaywa okuthile.

Lapho inani eliphelele le-CPK liphezulu kakhulu, imvamisa lisho ukuthi kube nokulimala noma ukucindezela kwezicubu zemisipha, inhliziyo, noma ubuchopho.

Ukulimala kwezicubu zemisipha kungenzeka kakhulu. Lapho imisipha yonakele, i-CPK iyavuza egazini. Ukuthola ukuthi yiluphi uhlobo oluthile lwe-CPK oluphezulu kusiza ukunquma ukuthi iziphi izicubu ezilimele.

Lokhu kuhlolwa kungasetshenziselwa uku:

• Thola ukuhlaselwa yinhliziyo
• Linganisa imbangela yobuhlungu besifuba
• Thola ukuthi imisipha yonakele noma yonakele kangakanani
• Thola i-dermatomyositis, i-polymyositis, nezinye izifo zemisipha
• Tshela umehluko phakathi kwe-hyperthermia ebulalayo nokutheleleka kwangemva kokuhlinzwa

Iphethini nesikhathi sokukhuphuka noma ukwehla kwamazinga e-CPK kungabonakala ekwenzeni ukuxilongwa. Lokhu kuyiqiniso ikakhulukazi uma kusolwa isifo senhliziyo.

Ezimweni eziningi kusetshenziswa ezinye izivivinyo esikhundleni noma ngalesi sivivinyo ukuthola isifo senhliziyo.

Ingqikithi yamanani ajwayelekile e-CPK:

• Ama-micrograms ayi-10 kuye kwayi-120 ilitha ngalinye (mcg / L)

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Amazinga aphezulu e-CPK angabonakala kubantu abane:

• Ukulimala kobuchopho noma isifo sohlangothi
• Ukudlikizela
• I-Delirium tremens
• Dermatomyositis noma i-polymyositis
• Ukushaqeka kukagesi
• Isifo senhliziyo
• Ukuvuvukala kwemisipha yenhliziyo (myocarditis)
• Ukufa kwezicubu zomzimba (i-infarction yamaphaphu)
• Ama-dystrophies emisipha
• I-Myopathy
• Ukuvuselelwa

Ezinye izimo ezinganikeza imiphumela emihle yokuhlolwa zifaka:

• I-Hypothyroidism
• I-Hyperthyroidism
• I-Pericarditis elandela isifo senhliziyo

Izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Olunye uvivinyo kufanele lwenziwe ukuthola indawo ngqo yokulimala kwemisipha.

Izici ezingathinta imiphumela yokuhlolwa zifaka i-catheterization yenhliziyo, imijovo ye-intramuscular, ukuhlukumezeka kwemisipha, ukuhlinzwa kwakamuva, nokuvivinya umzimba okunzima.

Ukuhlolwa kwe-CPK

• Ukuhlolwa kwegazi

U-Anderson JL. Ukuphakama kwesigaba se-St seakyo myocardial infarction nezinkinga ze-infarction ye-myocardial. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 73.

ICarty RP, iPincus MR, iSarafraz-Yazdi E.I-enzymology yomtholampilo. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. IPhiladelphia, PA: Elsevier; I-2017: isahluko 20.

IMccullough PA. Ukusebenzisana phakathi kwesifo sezinso nokugula kwenhliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2019: isahluko 98.

INagaraju K, iGladue HS, iLundberg IE. Izifo ezivuthayo zemisipha nezinye i-myopathies. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, abahleli. Incwadi kaKelley noFirestein yeRheumatology. Umhlaka 10. IPhiladelphia, PA: Elsevier Saunders; 2017: isahluko 85.