Iphaneli le-B-cell leukemia / lymphoma

Iphaneli le-B-cell leukemia / lymphoma luhlolo lwegazi olubheka amaprotheni athile ebusweni bamaseli amhlophe egazi abizwa nge-B-lymphocyte. Amaprotheni yizimpawu ezingasiza ukuxilonga i-leukemia noma i-lymphoma.

Kudingeka isampula yegazi.

Kwezinye izimo, amaseli amhlophe egazi asuswa ngesikhathi somnkantsha wamathambo. Isampula nayo ingathathwa ngesikhathi se-lymph node biopsy noma enye i-biopsy lapho kusolwa i-lymphoma.

Isampuli yegazi ithunyelwa elabhorethri, lapho uchwepheshe ehlola uhlobo lweseli nezici zalo. Le nqubo ibizwa ngokuthi yi-immunophenotyping. Ukuhlolwa kuvame ukwenziwa kusetshenziswa inqubo ebizwa nge- flow cytometry.

Akukho ukulungiselela okukhethekile okudingeka njalo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlolwa kungenziwa ngezizathu ezilandelayo:

• Lapho ezinye izivivinyo (njenge-smear yegazi) zikhombisa izimpawu zamaseli egazi amhlophe angajwayelekile
• Lapho kusolwa i-leukemia noma i-lymphoma
• Ukuthola uhlobo lwe-leukemia noma i-lymphoma

Imiphumela engajwayelekile ivamise ukukhombisa noma:

• I-B-cell lymphocytic leukemia
• I-Lymphoma

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Izimpawu ze-B lymphocyte surface surface; Ukugeleza kwe-cytometry - i-leukemia / lymphoma immunophenotyping

• Ukuhlolwa kwegazi

I-Appelbaum FR, uWalter RB. Ama-leukemias abukhali. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 173.

I-Bierman PJ, i-Armitage JO. Ama-non-Hodgkin lymphomas. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 176.

I-Connors JM. IHodgkin lymphoma. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 177.

UKussick SJ. Izimiso zokugeleza kwe-cytometric ku-hematopathology. Ku: Hsi ED, ed. I-Hematopathology. 3rd ed. IPhiladelphia, PA: Elsevier; 2018: isahluko 23.