Ukuhlolwa kwegazi le-Aldosterone

Ukuhlolwa kwegazi kwe-aldosterone kukala izinga le-hormone aldosterone egazini.

I-Aldosterone nayo ingalinganiswa kusetshenziswa ukuhlolwa komchamo.

Kudingeka isampula yegazi.

Umhlinzeki wakho wezokunakekelwa kwempilo angakucela ukuthi uyeke ukuthatha imithi ethile ezinsukwini ezimbalwa ngaphambi kokuhlolwa ukuze ingathinti imiphumela yokuhlolwa. Qiniseka ukuthi utshela umhlinzeki wakho ngayo yonke imithi oyiphuzayo. Lokhu kufaka phakathi:

• Imithi yomfutho wegazi ophezulu
• Imithi yenhliziyo
• Izidakamizwa ezingezona ukuvuvukala (ama-NSAID)
• Imithi elwa namagciwane nezilonda
• Amaphilisi wamanzi (isisu)

Ungayeki ukuthatha noma imuphi umuthi ngaphambi kokukhuluma nodokotela wakho. Umhlinzeki wakho angancoma ukuthi ungadli ngaphezu kuka-3 amagremu kasawoti (i-sodium) ngosuku okungenani amasonto ama-2 ngaphambi kokuhlolwa.

Noma, umhlinzeki wakho uzoncoma ukuthi udle inani lakho elijwayelekile likasawoti futhi uvivinye inani le-sodium emchameni wakho.

Ngezinye izikhathi, ukuhlolwa kwegazi kwe-aldosterone kwenziwa ngaphambi nangemva kokuthola isisombululo sikasawoti (usawoti) ngomthambo (IV) wamahora ama-2. Yazi ukuthi ezinye izinto zingathinta izilinganiso ze-aldosterone, kufaka phakathi:

• Ukukhulelwa
• Ukudla okuphezulu noma okuphansi kwe-sodium
• Ukudla okuphezulu noma okuphansi kwe-potassium
• Ukuzivocavoca okunzima
• Ukucindezeleka

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa behlatshwa noma bezwa nje kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlolwa kuhlelelwe lezi zimo ezilandelayo:

• Izinkinga ezithile ze-fluid ne-electrolyte, imvamisa iphansi noma iphakeme nge-sodium noma i-potassium ephansi
• Kunzima ukulawula umfutho wegazi
• Umfutho wegazi ophansi lapho umile (i-orthostatic hypotension)

I-Aldosterone iyi-hormone ekhishwa yizindlala ze-adrenal. Kuyasiza umzimba ukulawula umfutho wegazi. I-Aldosterone yandisa ukwenziwa kabusha kwe-sodium namanzi kanye nokukhishwa kwe-potassium ezinso. Lesi senzo siphakamisa umfutho wegazi.

Ukuhlolwa kwegazi kwe-Aldosterone kuvame ukuhlanganiswa nokunye ukuhlolwa, okufana nokuhlolwa kwe-hormone ye-renin, ukuxilonga ukukhiqizwa okweqile noma okungaphansi kwe-aldosterone.

Amazinga ajwayelekile ayahluka:

• Phakathi kwezingane, intsha, nabantu abadala
• Kuya ngokuthi ubumi, uhleli, noma ulele phansi lapho kudonswa igazi

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga eliphakeme kunejwayelekile le-aldosterone lingahle libe ngenxa ye:

• I-Bartter syndrome (iqembu lezimo ezingavamile ezithinta izinso)
• Izindlala ze-Adrenal zikhipha i-aldosterone hormone eningi kakhulu (i-hyperaldosteronism eyinhloko - imvamisa ngenxa yesibungu esibi ku-adrenal gland)
• Ukudla okuphansi kakhulu kwe-sodium
• Ukuthatha imithi yengcindezi yegazi ebizwa nge-mineralocorticoid antagonists

Izinga eliphansi kunejwayelekile le-aldosterone lingahle libe ngenxa ye:

• Izinkinga ze-adrenal gland, kufaka phakathi ukungakhiphi i-aldosterone eyanele, kanye nesimo esibizwa ngokuthi ukungasebenzi kahle kwe-adrenal (isifo i-Addison)
• Ukudla okuphezulu kakhulu kwe-sodium

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi kusuka kwesiguli kuya kwesinye nokusuka kolunye uhlangothi lomzimba kuye kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-Aldosterone - i-serum; Isifo i-Addison - i-serum aldosterone; I-hyperaldosteronism eyinhloko - i-serum aldosterone; I-Bartter syndrome - i-serum aldosterone

UCarey RM, uPadia SH. Ukuphazamiseka ngokweqile kwe-mineralocorticoid kanye nomfutho wegazi ophezulu. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 108.

UGuber HA, uFarag AF. Ukuhlolwa komsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 24.