I-Fosamprenavir

-Delile

• Ngaphambi kokuthatha i-fosamprenavir,
• I-Fosamprenavir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo.

IFosamprenavir isetshenziswa kanye neminye imithi yokwelapha ukutheleleka ngegciwane lesandulela ngculaza (i-HIV). I-Fosamprenavir isekilasini lemithi ebizwa nge-protease inhibitors. Isebenza ngokunciphisa inani le-HIV egazini.Yize i-fosamprenavir ingayelaphi i-HIV, ingahle inciphise amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengezifo ezibucayi noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko endleleni yokuphila kunganciphisa ingozi yokudlulisela igciwane le-HIV kwabanye abantu.

IFosamprenavir iza njengethebhulethi nokumiswa (uketshezi) ukuthatha ngomlomo. Kuvame ukuthathwa kanye noma kabili ngosuku. Amaphilisi angaphuzwa nokudla noma ngaphandle kokudla. Ezigulini okungenani ezineminyaka engu-18 ubudala, ukumiswa kufanele kuthathwe ngaphandle kokudla. Ezigulini ezingaphansi kweminyaka engu-18 ubudala, ukumiswa kufanele kuthathwe nokudla. Ukukusiza ukuthi ukhumbule ukuthatha i-fosamprenavir, yithathe ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-fosamprenavir njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma uthatha ukumiswa, kunyakazise kahle ngaphambi kokusebenzisa ngakunye ukuxuba umuthi ngokulinganayo.

Uma uhlanza ngaphansi kwemizuzu engama-30 ngemuva kokuthatha i-fosamprenavir, kufanele uthathe omunye umthamo ogcwele we-fosamprenavir.

IFosamprenavir ilawula ukutheleleka nge-HIV kepha ayiyelaphi. Qhubeka uthathe i-fosamprenavir noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-fosamprenavir ngaphandle kokukhuluma nodokotela wakho. Uma uphuthelwa amanani noma uyeka ukuthatha i-fosamprenavir, isimo sakho singaba nzima ukwelapha.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-fosamprenavir,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergies ku-fosamprenavir, amprenavir (Agenerase; ayisatholakali e-U.S.), imishanguzo yesulfa, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-fosamprenavir noma ukumiswa. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• tshela udokotela wakho uma uthatha i-alfuzosin (Uroxatral); i-cisapride (Propulsid) (ayitholakali e-US); i-delavirdine (i-Rescriptor); imithi ye-ergot efana ne-dihydroergotamine (i-DHE 45, i-Migranal), i-ergoloid mesylates (i-Hydergine), i-ergonovine, i-ergotamine (i-Ergomar, i-Cafergot, i-Migergot), ne-methylergonovine (Methergine); lomitapide (Juxtapid); i-lovastatin (Altoprev); i-midazolam (iVesi); ipimozide (i-Orap); i-rifampin (iRifadin, iRimactane, eRifater, eRifamate); i-sildenafil (uphawu lwe-Revatio kuphela olusetshenziselwa isifo samaphaphu); simvastatin (iZocor, eVytorin); ISt John's wort; noma i-triazolam (Halcion). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-fosamprenavir uma uthatha eyodwa noma ngaphezulu yale mithi.
• ungathathi i-flecainide, i-lurasidone (i-Latuda), noma i-propafenone (i-Rhythmol) uma nithatha i-fosamprenavir ne-ritonavir (i-Norvir) ndawonye.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokunganikezwa imishanguzo, amavithamini, nezithako zokudla okunomsoco okwenzayo. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); imishanguzo efana ne-amitriptyline, imipramine (Surmontil), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) ne-trazodone; i-atorvastatin (Lipitor, eCaduet); ama-antacids aqukethe i-aluminium ne-magnesium (Maalox, amanye); ama-benzodiazepines afana ne-alprazolam (Xanax), i-clorazepate (uGen-Xene, iTranxene), i-diazepam (iDiastat, iValium), ne-flurazepam; i-bosentan (iTracleer); ama-calcium channel blocker anjenge-amlodipine (Norvasc, e-Exforge, amanye), diltiazem (Cardizem, Cartia, Tiazac, others), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), nimodipine (Nymalize), nisoldipine (Sular), ne-verapamil (Calan, Covera, Verelan, eTarka); i-colchicine (Colcrys, Mitigare); i-dasatinib (i-Sprycel); i-dexamethasone; everolimus (Afinitor); i-fentanyl (i-Duragesic); i-fluticasone (i-Flonase, i-Flovent, e-Advair); i-histamine H2-receptor blockers efana ne-cimetidine, i-famotidine (i-Pepcid), i-nizatidine (i-Axid), ne-ranitidine (i-Zantac); ibrutinib (Imbruvica); itraconazole (Onmel, Sporanox); imishanguzo yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Nexterone, Pacerone), i-disopyramide (i-Norpace), i-lidocaine (i-Lidoderm; e-Xylocaine ne-Epinephrine), ne-quinidine (e-Nuedexta); ketoconazole (Nizoral); i-nilotinib (iTasigna); imithi yokuquleka efana ne-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, abanye), phenobarbital, ne-phenytoin (Dilantin, Phenytek); imithi ecindezela amasosha omzimba njenge-cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), noma i-tacrolimus (Astagraf XL, Prograf); i-methadone (i-Dolophine, i-Methadose); eminye imishanguzo yokwelapha i-HIV kubandakanya i-dolutegravir (Tivicay), efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), lopinavir (Kaletra), maraviroc (Selzentry), nelfinavir (Viracept), nevirapine (Viramune), raltegravir (Isentress) (ENorvir, eKaletra, eViekira Pak), naseSaquinavir (Invirase); imishanguzo ethile yokwelapha igciwane le-hepatitis C okubandakanya i-boceprevir (ayisatholakali e-U.S. I-Victrelis), i-paritaprevir (e-Viekira XR), ne-simeprevir (ayisatholakali e-U.S.; i-Olysio); amanye ama-phosphodiesterase inhibitors (PDE-5 inhibitors) asetshenziselwa ukungasebenzi kahle kwe-erectile njenge-sildenafil (Viagra), tadalafil (Cialis), ne-vardenafil (Levitra); i-quetiapine (iSeroquel); i-rifabutin (i-Mycobutin); i-salmeterol (iSerevent, e-Advair); i-tadalafil (i-Adcirca); futhi i-vinblastine. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-fosamprenavir, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imishanguzo oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma uke waba nesifo sikashukela noma i-hemophilia (isifo lapho igazi lingahlanganisi kahle), i-cholesterol ephezulu noma i-triglycerides, noma isifo sezinso noma sesibindi, kufaka phakathi i-hepatitis B noma i-C
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-fosamprenavir, shayela udokotela wakho. Akufanele uncelise ibele uma utheleleke nge-HIV noma uthatha i-fosamprenavir.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-fosamprenavir.
• kufanele wazi ukuthi i-fosamprenavir ingahle yehle ukusebenza kwezindlela zokuvimbela inzalo zomlomo (amaphilisi okulawula ukubeletha). Khuluma nodokotela wakho ngezinye izindlela zokuvimbela ukukhulelwa ngenkathi uthatha lo muthi.
• kufanele wazi ukuthi amafutha omzimba wakho angakhuphuka noma ahambele ezindaweni ezahlukahlukene zomzimba wakho njengamabele akho nomhlane ongaphezulu.
• kufanele wazi ukuthi ungathola i-hyperglycemia (iyanda kushukela wakho wegazi) ngenkathi uthatha lo muthi, noma ngabe awunaso vele isifo sikashukela. Tshela udokotela wakho ngokushesha uma unanoma iyiphi yalezi zimpawu ezilandelayo ngenkathi uthatha i-fosamprenavir: ukoma ngokweqile, ukuchama njalo, ukulamba ngokweqile, ukungaboni kahle, noma ubuthakathaka. Kubaluleke kakhulu ukubiza udokotela wakho ngokushesha uma unezinye zalezi zimpawu, ngoba ushukela wegazi ongelashwa ungadala isimo esibi esibizwa nge-ketoacidosis. I-Ketoacidosis ingasongela impilo uma ingelashwa kusenesikhathi. Izimpawu ze-ketoacidosis zifaka phakathi: umlomo owomile, isicanucanu nokuhlanza, ukuphefumula okuncane, ukuphefumula okunuka izithelo, nokuncipha kokwazi.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi noma kunini ngesikhathi sokwelashwa kwakho nge-fosamprenavir, qiniseka ukuthi utshela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Fosamprenavir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• isicanucanu
• ukuhlanza
• ikhanda
• ukukhathala ngokweqile

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo.

• ukuqubuka
• ukulunywa
• isifuba, amabhamuza, noma isikhumba esihlabayo
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kobuso bakho, amehlo, izindebe, ulimi, noma umphimbo
• umphimbo obuhlungu, umkhuhlane, amakhaza, ukukhwehlela, nezinye izimpawu zokutheleleka
• ubuhlungu emuva noma ohlangothini
• igazi emchameni
• ubuhlungu lapho uchama

I-Fosamprenavir ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ukumiswa nakho kungagcinwa esiqandisini, kepha ungakusimisi.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze aqiniseke ukuthi kuphephile yini kuwe ukuthatha i-fosamprenavir nokuhlola impendulo yomzimba wakho ku-fosamprenavir.

Ungaphelelwa yimithi. Lapho ukunikezwa kwakho kwe-fosamprenavir kuqala ukwehla, thola okuningi kudokotela wakho noma ekhemisi.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Lexiva^®