Isifo seWiskott-Aldrich

-Delile

• Izimpawu zeWiskott-Aldrich Syndrome
• Ukwelashwa kweWiskott-Aldrich Syndrome

I-Wiskott-Aldrich syndrome yisifo sofuzo, esibeka engcupheni amasosha omzimba afaka ama-lymphocyte ka-T no-B, namaseli egazi asiza ukulawula ukopha, ama-platelet.

Izimpawu zeWiskott-Aldrich Syndrome

Izimpawu ze-wiskott-Aldrich syndrome kungaba:

Ukuthambekela kokopha:

• Kuncishiswe inani nosayizi wegazi egazini;
• Ukopha okunganqamuki okubonakala ngamachashazi abomvu noluhlaza okwesibhakabhaka alingana nekhanda lephini, elibizwa nge- “petechiae”, noma angaba makhulu futhi afane nemihuzuko;
• Izindle ezinegazi (ikakhulukazi ebuntwaneni), izinsini ezophayo kanye nemiphunga ekhaleni ende.

Ukutheleleka okuvamile okubangelwa yizo zonke izinhlobo zamagciwane amancane njenge:

• Otitis media, sinusitis, inyumoniya;
• I-Meningitis, i-pneumonia ebangelwa yi-Pneumocystis jiroveci;
• Ukutheleleka kwesikhumba okubangelwa yi-molluscum contagiosum.

I-eczema:

• Ukutheleleka njalo kwesikhumba;
• Amabala amnyama esikhunjeni.

Ukubonakaliswa okuzenzakalelayo:

• I-Vasculitis;
• I-hemolytic anemia;
• Idiopathic thrombocytopenic purpura.

Ukuxilongwa kwalesi sifo kungenziwa udokotela wezingane ngemuva kokubona izimpawu nezimpawu ezithile. Ukuhlola ubukhulu bama-platelet kungenye yezindlela zokuxilonga lesi sifo, njengoba zimbalwa izifo ezinalesi sici.

Ukwelashwa kweWiskott-Aldrich Syndrome

Ukwelashwa okufanele kakhulu kwe-Wiskott-Aldrich syndrome ukufakelwa umnkantsha wethambo. Ezinye izindlela zokwelashwa ukususwa kobende, njengoba lesi sitho sibulala inani elincane lama-platelet abantu abanalesi sifo abanalo, ukusetshenziswa kwe-hemoglobin nokusetshenziswa kwama-antibiotic.

Isikhathi sokuphila sabantu abanalesi sifo siphansi, labo abasinda ngemuva kweminyaka eyishumi bavame ukuba nezicubu ezifana ne-lymphoma ne-leukemia.