Inaliti ye-Abatacept

-Delile

• Ngaphambi kokusebenzisa i-abatacept,
• I-Abatacept ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-Abatacept isetshenziswa yodwa noma ihlanganiswe neminye imithi yokwehlisa ubuhlungu, ukuvuvukala, ubunzima ngemisebenzi yansuku zonke, kanye nomonakalo ohlangene odalwe yi-rheumatoid arthritis (isimo lapho umzimba uhlasela khona amalunga ayo obangela ubuhlungu, ukuvuvukala, nokulahleka komsebenzi) kubantu abadala abangazange basizwe ngeminye imithi. Ibuye isetshenziswe yodwa noma ihlanganiswe ne-methotrexate (Trexall) ukwelapha i-polyarticular juvenile idiopathic arthritis (i-PJIA; uhlobo lwesifo samathambo ebuntwaneni oluthinta amalunga amahlanu noma ngaphezulu phakathi nezinyanga eziyisithupha zokuqala zalesi simo, kubangela ubuhlungu, ukuvuvukala nokulahleka function) ezinganeni ezineminyaka engu-2 noma ngaphezulu. I-Abatacept nayo isetshenziswa yodwa noma ihlanganiswe neminye imithi yokwelapha i-psoriatic arthritis (isimo esidala ubuhlungu bamalunga nokuvuvukala nezikali esikhunjeni) kubantu abadala. I-Abatacept isekilasini lemithi ebizwa ngokuthi yi-selective costimulation modulators (ama-immunomodulators). Isebenza ngokuvimba ukusebenza kwama-T-cell, uhlobo lwamaseli omzimba emzimbeni abangela ukuvuvukala nokulimala okuhlangene kubantu abane-arthritis.

I-Abatacept iza njengempuphu ezohlanganiswa namanzi oyinyumba okufanele inikezwe ngemithambo yegazi (emthanjeni) nanjengesixazululo (uketshezi) esirinji ekhethiwe noma i-autoinjector okufanele inikezwe ngomgogodla (ngaphansi kwesikhumba). Imvamisa inikezwa ngudokotela noma umhlengikazi ehhovisi likadokotela noma esikhungweni sokunakekelwa kwezempilo lapho unikezwa ngemithambo yegazi. Ngiphinde nginikezwe ngudokotela noma umhlengikazi ngaphansi kwakho noma wena noma umnakekeli ungatshelwa ukuthi ujove umuthi ngaphansi komgwaqo ekhaya. Lapho i-abatacept inikezwa ngemithambo yegazi ukuphatha i-rheumatoid arthritis noma i-psoriatic arthritis, imvamisa inikezwa njalo emavikini ama-2 ngemithamo emithathu yokuqala bese njalo njalo emavikini amane uma nje ukwelashwa kuqhubeka. Lapho i-abatacept inikezwa ngemithambo yokwelapha i-polyarticular juvenile idiopathic arthritis ezinganeni ezineminyaka engu-6 nangaphezulu, imvamisa inikezwa njalo emavikini amabili ngemithamo emibili yokuqala bese njalo njalo emavikini amane inqobo nje uma ukwelashwa kuqhubeka. Kuzothatha cishe imizuzu engama-30 ukuthola wonke umthamo wakho we-abatacept ngemithambo. Lapho i-abatacept inikezwa ngaphansi kwesikhashana ukwelapha i-rheumatoid arthritis noma i-psoriatic arthritis kubantu abadala kanye ne-polyarticular juvenile idiopathic arthritis ezinganeni ezineminyaka engu-2 nangaphezulu, imvamisa inikezwa kanye ngesonto.

Uma uzobe ujova umjovo we-abatacept uwedwa ekhaya noma unomngane noma isihlobo sikufakela umuthi, cela udokotela wakho akubonise noma umuntu ozokujova umuthi ukuthi ungawujova kanjani. Wena kanye nomuntu ozojova umuthi kufanele futhi ufunde imiyalo ebhaliwe yomkhiqizi yokusetshenziswa eza nomuthi.

Ngaphambi kokuthi uvule iphakethe eliqukethe imishanguzo yakho, hlola ukuqinisekisa ukuthi usuku lokuphelelwa yisikhathi oluphrintwe kwiphakheji aludlulanga. Ngemuva kokuvula iphakethe, bhekisisa uketshezi olukusipontsho. Okuketshezi kufanele kucace noma kuphuzi ngokukhanyayo futhi akufanele kube nezinhlayiya ezinkulu ezinemibala. Shayela usokhemisi wakho, uma kunezinkinga ngephakethe noma ngesirinji. Musa ukujova umuthi.

Ungajova umjovo we-abatacept noma kuphi esiswini noma emathangeni akho ngaphandle kwenkaba yakho (inkinobho yesisu) nendawo engamasentimitha ama-2 ukuyizungeza. Uma omunye umuntu ezokujolela umuthi, lowo muntu angawufaka futhi engxenyeni engaphandle yengalo yakho ephezulu. Sebenzisa indawo ehlukile ngomjovo ngamunye. Ungafaki umjovo we-abatacept endaweni ethambile, elimele, ebomvu noma eqinile. Futhi, musa ukujova ezindaweni ezinezibazi noma izimpawu zokwelula.

Susa isirinji efakiwe noma i-autoinjector efakwe efrijini bese uyivumela ukuba ifudumale ekamelweni lokushisa imizuzu engama-30 ngaphambi kokuyisebenzisa. Ungafaki umjovo ofudumele we-abatacept emanzini ashisayo, i-microwave, noma uyibeke elangeni. Ungasusi ikhava yenaliti ngenkathi uvumela isirinji ekhethiwe ukuthi ifinyelele ithempelesha yasekamelweni.

Udokotela wakho uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi ukuze ulifunde ngaphambi kokuthola umthamo ngamunye we-abatacept. Funda imininingwane ngokucophelela bese ubuza udokotela wakho noma yimiphi imibuzo onayo.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-abatacept,

• Tshela udokotela wakho kanye nosokhemisi uma unalelastacept, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-abatacept. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: anakinra (Kineret), adalimumab (Humira), etanercept (Enbrel), ne-infliximab (Remicade). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma unesifo noma yikuphi emzimbeni, kufaka phakathi izifo ezifika futhi zidlule, njengezilonda ezibandayo, nezifo ezingapheli ezingapheli, noma uma uvame ukuthola noma yiluphi uhlobo lokutheleleka okufana nezifo zesinye. Phinda utshele udokotela wakho uma uke waba nesifo esingapheliyo sokuphazamiseka kwamaphaphu (COPD; iqembu lezifo zamaphaphu ezibandakanya i-bronchitis engapheli ne-emphysema); noma yisiphi isifo esithinta isimiso sakho sezinzwa, njenge-multiple sclerosis; noma yisiphi isifo esithinta amasosha akho omzimba, njengomdlavuza, igciwane lesandulela ngculazi (i-HIV), i-immunodeficiency syndrome (i-AIDS), noma i-immunodeficiency syndrome (i-SCID) ehlangene kakhulu. Phinda utshele udokotela wakho uma uke waba nesifo sofuba noma owake waba naso (i-TB; ukutheleleka kwamaphaphu okungase kungabangeli izimpawu iminyaka eminingi futhi okungase kusabalale nakwezinye izingxenye zomzimba) noma ngabe ubukade useduze komuntu onesifo sofuba noma onesifo sofuba . Udokotela wakho angakuhlola isikhumba ukuze abone ukuthi ungenwe yini yisifo sofuba. Tshela udokotela wakho uma wake wahlolwa kahle isifo sofuba esikhathini esidlule.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-abatacept, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-abatacept.
• utshele udokotela wakho uma usanda kuthola noma uhlelelwe ukuthola noma yimiphi imithi yokugoma. Akufanele ube neminye imigomo ngenkathi usebenzisa i-abatacept noma izinyanga ezintathu ngemuva kwesilinganiso sakho sokugcina se-abatacept ngaphandle kokukhuluma nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uthola i-abatacept ngemithambo yegazi futhi uphuthelwa i-aphoyintimenti yokuthola ukumuncwa kwe-abatacept, shayela udokotela wakho ngokushesha okukhulu.

Uma uthola i-abatacept ngasese bese uphuthelwa umthamo, buza udokotela wakho uhlelo olusha lokulinganisa.

I-Abatacept ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ikhala eligijimayo
• Umphimbo obuhlungu
• isicanucanu
• isiyezi
• isilungulela
• ukuhlungu obusemhlane
• ubuhlungu bengalo noma bomlenze

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka kwesikhumba
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, noma umphimbo
• ukuphefumula kanzima noma ukugwinya
• ukuphelelwa umoya
• umkhuhlane, ukubanda, nezinye izimpawu zokutheleleka
• ukukhwehlela okomile okungapheli
• ukuncipha komzimba
• ukujuluka ebusuku
• ukuchama kaningi noma isidingo ngokungazelelwe sokuchama ngokushesha
• ukuvutha ngesikhathi sokuchama
• i-cellulitis (indawo ebomvu, eshisayo, evuvukile esikhumbeni)

I-Abatacept ingakhuphula ubungozi bokuthuthukisa izinhlobo ezithile zomdlavuza kubandakanya i-lymphoma (umdlavuza oqala kumaseli alwa nokutheleleka) nomdlavuza wesikhumba. Abantu asebenesifo samathambo esinzima isikhathi eside bangaba nengozi enkulu kunokujwayelekile yokuthola lawa mdlavuza noma bengasebenzisi i-abatacept. Udokotela wakho uzohlola isikhumba sakho nganoma yiziphi izinguquko phakathi nokwelashwa kwakho. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi.

I-Abatacept ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Gcina imijovo ekhethiwe kanye nama-autoinjectors kwikhathoni yoqobo efike kuyo ukuze ibavikele ekukhanyeni nasekufinyelelekeni kwezingane. Gcina imijovo yokugcotshwa kwe-abatacept noma ama-autoinjectors esiqandisini futhi ungagodoli.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-abatacept.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi usebenzisa umjovo we-abatacept.

Uma unesifo sikashukela futhi uthola i-abatacept ngemithambo, umjovo we-abatacept unganikeza ukufundwa kweglucose egazini elingamanga ngosuku lokumnika kwakho. Khuluma nodokotela wakho noma usokhemisi mayelana nokuhlolwa kokuhlolwa kokuhlolwa kweglucose kwegazi lapho usetshenziswa ukwelashwa kwakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Orencia^®