Inaliti eyinkimbinkimbi ye-Doxorubicin Lipid

-Delile

• Ngaphambi kokuthola i-doxorubicin lipid complex,
• I-Doxorubicin lipid complex ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Doxorubicin lipid complex ingadala izinkinga zenhliziyo ezinkulu noma ezisongela impilo nganoma yisiphi isikhathi phakathi nokwelashwa kwakho noma izinyanga kuya eminyakeni ngemuva kokuphela kokwelashwa kwakho. Udokotela wakho uzoku-oda ukuhlolwa ngaphambi nangesikhathi sokwelashwa kwakho ukuze abone ukuthi inhliziyo yakho isebenza kahle ngokwanele yini ukuthola ngokuphepha i-doxorubicin lipid complex Lezi zivivinyo zingafaka i-electrocardiogram (ECG; isivivinyo esiqopha umsebenzi kagesi wenhliziyo) kanye ne-echocardiogram ( test esebenzisa amaza omsindo ukukala amandla enhliziyo yakho okumpompa igazi). Udokotela wakho angakutshela ukuthi akufanele uthole le mithi uma izivivinyo zibonisa ukuthi amandla enhliziyo yakho okupompa igazi anciphile. Tshela udokotela wakho uma ngabe uke waba nanoma yiluphi uhlobo lwesifo senhliziyo noma ukwelashwa ngemisebe (x-ray) endaweni yesifuba. Tshela udokotela kanye nosokhemisi wakho uma uthatha noma wake wathola imithi ethile yokwelashwa ngamakhemikhali njenge-cyclophosphamide (Cytoxan), i-daunorubicin (i-Cerubidine, i-DaunoXome), i-epirubicin (i-Ellence), i-idarubicin (i-Idamycin), i-mitoxantrone (i-Novantrone), i-paclitaxel (i-Abraxane I-Onxol), i-trastuzumab (i-Herceptin), noma i-verapamil (i-Calan, i-Isoptin). Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuphefumula okuncane; ukuphefumula kanzima; ukuvuvukala kwezandla, izinyawo, amaqakala noma imilenze engezansi; noma ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla.

Ungase uzwe ukusabela okweqile okwedlulele ngenkathi uthola umthamo we-doxorubicin lipid injection injection. Tshela udokotela wakho noma umhlengikazi ngokushesha uma uhlangabezana nalezi zimpawu ngenkathi uthola i-doxorubicin lipid complex: isifuba; ukuqubuka; ukulunywa; ukuvuvukala kobuso, amehlo, umlomo, umphimbo, ulimi, noma izindebe; ukuqhuma; imfiva; Ukugodola; ukuhlungu obusemhlane; ikhanda; ubunzima bokuphefumula noma ukugwinya; ukuphelelwa umoya; noma ukuqina kwesifuba.

I-Doxorubicin ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho. Udokotela wakho uzo-oda izivivinyo zaselebhu njalo ngaphambi nangesikhathi sokwelashwa kwakho. Ukwehla kwenani lamaseli egazi emzimbeni wakho kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okunzima noma ukopha. Tshela udokotela kanye nosokhemisi wakho uma uthatha noma uthole i-azathioprine (Imuran), cyclosporine (Neoral, Sandimmune), methotrexate (Rheumatrex), noma i-progesterone (Provera, Depo-Provera). Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokuminyana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulimaza; ezinegazi noma ezimnyama, izitulo zokulinda; ukuhlanza kwegazi; noma ukugabha igazi noma okokusundu okufana nezindawo zekhofi.

Tshela udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso. Udokotela wakho angadinga ukushintsha umthamo wakho uma unesifo sesibindi.

I-Doxorubicin lipid complex isetshenziselwa ukwelapha umdlavuza we-ovari ongakathuthuki noma oye waba mubi ngemuva kokwelashwa ngeminye imithi. IDoxorubicin lipid complex nayo isetshenziselwa ukwelapha iKaposi’s sarcoma (uhlobo lomdlavuza oludala izicubu ezingajwayelekile ukuba zikhule ezingxenyeni ezihlukene zomzimba) ezihlobene ne-immunodeficiency syndrome (AIDS) engakathuthuki noma eye yaba yimbi kakhulu ngemuva kokwelashwa ngeminye imithi. I-Doxorubicin lipid complex nayo ihlanganiswe nomunye umuthi wokwelapha ngamakhemikhali ukwelapha i-myeloma eminingi (uhlobo lomdlavuza womnkantsha wethambo) ongakathuthuki noma osuke waba muncu ngemuva kokwelashwa ngeminye imithi. I-Doxorubicin lipid complex isekilasini lemithi ebizwa ngama-anthracyclines. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

IDoxorubicin lipid complex iza njengoketshezi oluzofakwa ngaphakathi (emthanjeni) ngaphezu kwehora elilodwa ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Lapho i-doxorubicin lipid complex isetshenziselwa ukwelapha umdlavuza we-ovari, inikezwa kanye njalo emavikini amane. Lapho i-doxorubicin lipid complex isetshenziswa ukwelapha i-Kaposi's sarcoma, inikezwa kanye njalo emavikini amathathu. Lapho i-doxorubicin lipid complex isetshenziselwa ukwelapha i-myeloma eminingi, inikezwa ngezinsuku ezithile njalo emavikini amathathu.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-doxorubicin lipid complex,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-doxorubicin, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-doxorubicin lipid complex. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nanoma yikuphi okulandelayo: imishanguzo ethile yamakhemikhali afana ne-cytarabine (DepoCyt), dexrazoxane (Zinecard), mercaptopurine (Purinethol), streptozocin (Zanosar); i-phenobarbital (i-Luminal Sodium); noma i-phenytoin (i-Dilantin). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo nayo ingaxhumana ne-doxorubicin lipid complex, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• tshela udokotela wakho uma ngabe uke waba nanoma yiziphi ezinye izimo zezokwelapha.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe noma uncelise ibele ngenkathi uthola i-doxorubicin lipid complex. Uma ukhulelwa ngenkathi uthola i-doxorubicin lipid complex, shayela udokotela wakho. I-Doxorubicin lipid complex ingalimaza umbungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Doxorubicin lipid complex ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukulahlekelwa ukudla (noma ukunciphisa umzimba)
• isicanucanu
• ukuhlanza
• ubuhlungu besisu
• isifo sohudo
• ukuqunjelwa
• ukukhathala okungajwayelekile noma ubuthakathaka
• isiyezi
• ukulahleka kwezinwele
• ekhaleni
• umbala omnyama obomvu noma owolintshi womchamo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• izilonda emlonyeni nasemphinjeni
• ukuluma, ukushisa, ubomvu, ukuvuvukala, ukuxebuka noma ukuqhuma, amabhamuza, noma izilonda ezintendeni zezandla noma ematheni ezinyawo
• ubuhlungu, ukulunywa, ububomvu, ukuvuvukala, amabhamuza, noma izilonda endaweni lapho kwafakwa khona umuthi

I-Doxorubicin lipid complex ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• izilonda emlonyeni nasemphinjeni
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• igazi elibomvu endle
• ukuhlanza okunegazi
• okokuhlanza okubukeka njengezizathu zekhofi

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-doxorubicin lipid complex.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Doxil^®