Vinblastine

-Delile

• Ngaphambi kokuthola i-vinblastine,
• IVinblastine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

IVinblastine kufanele ifakwe emthanjeni kuphela. Kodwa-ke, ingahle ivuze izicubu eziseduze ezibangele ukucasuka okukhulu noma ukulimala. Udokotela wakho noma umhlengikazi uzoqapha indawo yakho yokuphatha ngale ndlela. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ubuhlungu, ukulunywa, ubomvu, ukuvuvukala, amabhamuza, noma izilonda endaweni lapho umjovo wafakwa khona.

I-Vinblastine kufanele inikezwe kuphela ngaphansi kweso lodokotela onolwazi ekusetshenzisweni kwemithi yokwelapha ngamakhemikhali.

I-Vinblastine isetshenziswa ngokuhlangana neminye imithi yokwelapha ngamakhemikhali ukwelapha i-Hodgkin's lymphoma (isifo sikaHodgkin's) kanye ne-non-Hodgkin's lymphoma (izinhlobo zomdlavuza eziqala ngohlobo lweseli elimhlophe legazi ngokuvamile elilwa nokutheleleka), nomdlavuza wamasende. Ibuye isetshenziselwe ukwelapha i-Langerhans cell histiocytosis (i-histiocytosis X; isifo se-Letterer-Siwe; isimo lapho kukhula khona izinhlobo eziningi kakhulu zeseli elimhlophe ezingxenyeni zomzimba). Ingasetshenziselwa ukwelapha umdlavuza webele ongazange uthuthuke ngemuva kokwelashwa ngeminye imishanguzo kanye nezicubu zomzimba ezikhulelwe (uhlobo lwesimila olwenzeka ngaphakathi kwesibeletho sowesifazane ngenkathi ekhulelwe) olungakathuthuki ngemuva kokuhlinzwa noma ukwelashwa ngeminye imithi. IVinblastine isekilasini lemithi ebizwa nge-vinca alkaloids. Isebenza ngokunciphisa noma ukumisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

I-Vinblastine iza njengempuphu noma isisombululo (uketshezi) ezofakwa ngaphakathi (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Imvamisa inikezwa kanye ngesonto. Ubude bokwelashwa buxhomeke ezinhlotsheni zemithi oyiphuzayo, ukuthi umzimba wakho uphendula kahle kangakanani kuyo, nohlobo lomdlavuza onawo.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma ushintshe umthamo wakho uma uhlangabezana nemiphumela ethile emibi.Kubalulekile ukuthi utshele udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa ngomjovo we-vinblastine.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

I-Vinblastine nayo kwesinye isikhathi isetshenziselwa ukwelapha umdlavuza wesinye, izinhlobo ezithile zomdlavuza wamaphaphu, i-Kaposi's sarcoma, nezicubu ezithile zobuchopho. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-vinblastine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-vinblastine, noma imuphi omunye umuthi, noma yiziphi izithako zomjovo we-vinblastine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-aprepitant (Emend), ama-antifungal athile afana ne-itraconazole (Sporanox) ne-ketoconazole (i-Nizoral); i-clarithromycin (i-Biaxin, ku-Prevpac); i-erythromycin (E.E.S., E-Mycin, abanye); I-HIV protease inhibitors efaka i-indinavir (Crixivan), nelfinavir (Viracept), ne-ritonavir (Norvir, eKaletra); i-phenytoin (i-Dilantin), i-tolterodine (i-Detrol, i-Detrol LA). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Tshela udokotela wakho kanye nosokhemisi ngayo yonke imithi oyiphuzayo ukuze bakwazi ukubheka ukuthi ngabe ikhona yini imishanguzo yakho engakhuphula ubungozi bokuthi uzoba nezinkinga zokuzwa ngesikhathi sokwelashwa kwakho nge-vinblastine.
• utshele udokotela wakho uma unesifo. Udokotela wakho uzofuna ukwelapha ukutheleleka kwakho ngaphambi kokuthola umjovo we-vinblastine.
• Tshela udokotela wakho uma uke waba nesifo senhliziyo noma semithambo yegazi, kufaka phakathi imithambo ye-varicose (ukuvuvukala, ukubomvu, noma ubuhlungu emthanjeni ezandleni noma emilenzeni), noma isifo samaphaphu noma sesibindi.
• kufanele wazi ukuthi i-vinblastine ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini (isikhathi) kwabesifazane futhi ingamisa okwesikhashana noma unomphela ukukhiqizwa kwesidoda emadodeni. Tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma ukuncelisa. Akufanele ukhulelwe noma uncelise ibele ngenkathi uthola umjovo we-vinblastine. Uma ukhulelwa ngenkathi uthola umjovo we-vinblastine, shayela udokotela wakho. IVinblastine ingalimaza umbungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

IVinblastine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqunjelwa
• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla noma isisindo
• ubuhlungu besisu
• isifo sohudo
• ikhanda
• isiyezi
• ubuhlungu bomhlathi, ubuhlungu bamathambo, nobunye ubuhlungu
• ukulahleka kwezinwele

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• izilonda emlonyeni
• ukukhathala okungajwayelekile noma ubuthakathaka
• ubuhlungu, ukuba ndikindiki, ukushiswa, noma ukuhayiza ezandleni noma ezinyaweni
• ukuhamba kanzima noma ukuhamba ungagxilile
• ukuphefumula kanzima
• ukulahlekelwa ukuzwa
• isithuthwane
• ubuhlungu besifuba

IVinblastine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukudideka
• isithuthwane
• ukuqunjelwa
• ubuhlungu besisu
• ukopha okungajwayelekile noma ukulinyazwa
• umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-vinblastine.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Velban^®¶

• I-Vincaleukoblastine Sulfate
• I-VLB

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.