Ukuhlolwa kweCortisol

-Delile

• Kuyini ukuhlolwa kwe-cortisol?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwe-cortisol?
• Kwenzekani ngesikhathi sokuhlolwa kwe-cortisol?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi esivivinyweni?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwe-cortisol?
• Izinkomba

Kuyini ukuhlolwa kwe-cortisol?

ICortisol yihomoni ethinta cishe zonke izitho nezicubu emzimbeni wakho. Idlala indima ebalulekile ekusizeni ukuthi:

• Phendula ekucindezelekeni
• Yilwa nokutheleleka
• Lawula ushukela wegazi
• Gcina umfutho wegazi
• Lawula imetabolism, inqubo yokuthi umzimba wakho usebenzisa kanjani ukudla namandla

ICortisol yenziwa yizindlala zakho ze-adrenal, izindlala ezimbili ezincane ezingaphezulu kwezinso. Ukuhlolwa kwe-cortisol kukala izinga le-cortisol egazini lakho, emchameni noma ematheni. Ukuhlolwa kwegazi kuyindlela ejwayelekile yokulinganisa i-cortisol. Uma amazinga akho e-cortisol ephezulu kakhulu noma ephansi kakhulu, kungasho ukuthi unenkinga yezindlala zakho ze-adrenal. Lokhu kuphazamiseka kungaba kubi uma kungalashwa.

Amanye amagama: i-cortisol yomchamo, i-salivary cortisol, i-cortisol yamahhala, isivivinyo sokucindezela i-dexamethasone, i-DST, i-ACTH test stimulation, i-cortisol yegazi, i-plasma cortisol, i-plasma

Kusetshenziselwa ini?

Ukuhlolwa kwe-cortisol kusetshenziselwa ukusiza ukuxilonga ukuphazamiseka kwendlala ye-adrenal. Lokhu kufaka phakathi i-Cushing's syndrome, isimo esidala ukuthi umzimba wakho wenze i-cortisol eningi kakhulu, nesifo i-Addison, isimo lapho umzimba wakho ungenzi i-cortisol eyanele.

Kungani ngidinga ukuhlolwa kwe-cortisol?

Ungahle udinge ukuhlolwa kwe-cortisol uma unezimpawu zesifo sikaCushing's syndrome noma i-Addison.

Izimpawu ze-Cushing's syndrome zifaka:

• Ukukhuluphala ngokweqile, ikakhulukazi esifubeni
• Umfutho wegazi ophezulu
• Ushukela ophakeme wegazi
• Imibala eluhlaza okwesibhakabhaka esiswini
• Isikhumba esilimaza kalula
• Ubuthakathaka bemisipha
• Abesifazane bangaba nezikhathi ezingajwayelekile zokuya esikhathini nezinwele ezeqile ebusweni

Izimpawu zesifo i-Addison zifaka:

• Ukwehla kwesisindo
• Ukukhathala
• Ubuthakathaka bemisipha
• Ubuhlungu besisu
• Amabala amnyama esikhumba
• Umfutho wegazi ophansi
• Isicanucanu nokuhlanza
• Uhudo
• Ukwehla kwezinwele zomzimba

Ungadinga futhi ukuhlolwa kwe-cortisol uma unezimpawu zenkinga ye-adrenal, isimo esisongela impilo esingenzeka lapho amazinga akho e-cortisol ephansi kakhulu. Izimpawu zenkinga ye-adrenal zifaka:

• Umfutho wegazi ophansi kakhulu
• Ukuhlanza okukhulu
• Uhudo olunzima
• Ukuphela kwamanzi emzimbeni
• Ubuhlungu obungazelelwe nobunzima esiswini, eqolo nasemlenzeni
• Ukudideka
• Ukulahlekelwa ukwazi

Kwenzekani ngesikhathi sokuhlolwa kwe-cortisol?

Ukuhlolwa kwe-cortisol kuvame ukuba sohlolweni lwegazi. Ngesikhathi sokuhlolwa kwegazi, uchwepheshe wezokunakekelwa kwempilo uzothatha isampuli yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngoba amazinga e-cortisol ayashintsha usuku lonke, isikhathi sokuhlolwa kwe-cortisol kubalulekile. Ukuhlolwa kwegazi le-cortisol kuvame ukwenziwa kabili ngosuku –kanye ekuseni lapho amazinga e-cortisol esezingeni eliphezulu kakhulu, aphinde futhi ngabo-4 ntambama, lapho amazinga esephansi kakhulu.

ICortisol nayo ingalinganiswa ekuhlolweni komchamo noma kwamathe. Ukuhlolwa komchamo we-cortisol, umhlinzeki wakho wezokunakekelwa kwempilo angakucela ukuthi uqoqe wonke umchamo ngesikhathi samahora angama-24. Lokhu kubizwa ngokuthi "ukuhlolwa kwesampula yomchamo wamahora angama-24." Isetshenziswa ngoba amazinga e-cortisol ayahluka usuku lonke. Kulesi sivivinyo, umhlinzeki wakho wezokunakekelwa kwempilo noma uchwepheshe waselabhoratri uzokunika isitsha sokuqoqa umchamo wakho kanye nemiyalelo yokuthi ungawalanda kanjani futhi uwagcine amasampula akho. Ukuhlolwa kwesampula yamahora angama-24 kuvame ukufaka lezi zinyathelo ezilandelayo:

• Khipha isinye sakho ekuseni bese ususa lowo mchamo kude. Qopha isikhathi.
• Emahoreni angama-24 alandelayo, gcina wonke umchamo wakho odluliswe esitsheni osinikeziwe.
• Gcina isitsha sakho somchamo esiqandisini noma endaweni epholile eneqhwa.
• Buyisela isitsha sesampula ehhovisi lomhlinzeki wakho wezempilo noma elabhorethri njengoba kuyalelwe.

Ukuhlolwa kwamathe kwe-cortisol kuvame ukwenziwa ekhaya, ebusuku kakhulu, lapho amazinga e-cortisol ephansi. Umhlinzeki wakho wezokunakekelwa kwempilo uzokuncoma noma akunikeze ikhithi yalolu vivinyo. Ikhithi izofaka phakathi i-swab yokuqoqa isampula yakho kanye nesiqukathi ukusigcina. Izinyathelo zivame ukufaka okulandelayo:

• Ungadli, ungaphuzi, noma uxubha amazinyo akho imizuzu eyi-15-30 ngaphambi kokuhlolwa.
• Qoqa isampula phakathi kuka-11 ebusuku. naphakathi kwamabili, noma njengokuyalelwa ngumhlinzeki wakho.
• Faka i-swab emlonyeni wakho.
• Gingqa iswabi emlonyeni wakho cishe imizuzu emibili ukuze ikwazi ukumbozwa ngamathe.
• Ungathinti ichopho le-swab ngeminwe yakho.
• Faka i-swab esitsheni ngaphakathi kwekhithi bese uyibuyisela kumhlinzeki wakho njengoba eyalelwe.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Ukucindezeleka kungakhuphula amazinga akho e-cortisol, ngakho-ke kungadingeka ukuthi uphumule ngaphambi kokuhlolwa kwakho. Ukuhlolwa kwegazi kuzodinga ukuthi uhlele ama-aphoyintimenti amabili ngezikhathi ezahlukahlukene zosuku. Ukuhlolwa umchamo namathe amahora angama-24 kwenziwa ekhaya. Qiniseka ukuthi ulandela yonke imiyalo enikezwe umhlinzeki wakho.

Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha. Azikho izingozi ezaziwayo ekuhlolweni komchamo noma kwamathe.

Isho ukuthini imiphumela?

Amazinga aphezulu e-cortisol angasho ukuthi une-Cushing’s syndrome, kanti amazinga aphansi angasho ukuthi unesifo i-Addison noma olunye uhlobo lwesifo i-adrenal. Uma imiphumela yakho ye-cortisol ingejwayelekile, akusho ukuthi unesimo sezempilo esidinga ukwelashwa. Ezinye izinto, kufaka phakathi ukutheleleka, ukucindezeleka, nokukhulelwa kungathinta imiphumela yakho. Amaphilisi okulawula ukubeletha kanye neminye imithi nayo ingathinta amazinga akho e-cortisol. Ukuze ufunde ukuthi imiphumela yakho isho ukuthini, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwe-cortisol?

Uma amazinga akho e-cortisol angajwayelekile, umhlinzeki wakho wokunakekelwa kwezempilo kungenzeka a-oda izivivinyo eziningi ngaphambi kokwenza ukuxilongwa. Lezi zivivinyo zingafaka ukuhlolwa okwengeziwe kwegazi nomchamo nokuhlolwa kwe-imaging, okufana nokuhlolwa kwe-CT (computerised tomography) kanye ne-MRI (magnetic resonance imaging), evumela umhlinzeki wakho ukuthi abheke izindlala zakho ze-adrenal ne-pituitary.

Izinkomba

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Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.