Ukuhlolwa kweGamma-glutamyl Transferase (GGT)

-Delile

• Kuyini ukuhlolwa kwe-gamma-glutamyl transferase (GGT)?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwe-GGT?
• Kwenzekani ngesikhathi sokuhlolwa kwe-GGT?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi ekuhlolweni kwe-GGT?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-GGT?
• Izinkomba

Kuyini ukuhlolwa kwe-gamma-glutamyl transferase (GGT)?

Ukuhlolwa kwe-gamma-glutamyl transferase (GGT) kukala inani le-GGT egazini. I-GGT iyi-enzyme etholakala emzimbeni wonke, kepha itholakala kakhulu esibindini. Lapho isibindi sonakele, i-GGT ingavuza egazini. Izinga eliphakeme le-GGT egazini kungaba uphawu lwesifo sesibindi noma ukulimala kwamapayipi enyongo. Amapayipi ama-bile amashubhu angena ngaphakathi nangaphandle kwesibindi. Inyongo wuketshezi olwenziwa isibindi. Kubalulekile ukugaya.

Ukuhlolwa kwe-GGT akukwazi ukuxilonga imbangela ethile yesifo sesibindi. Ngakho-ke kuvame ukwenziwa kanye noma ngemuva kokuhlolwa kokusebenza kwesibindi, imvamisa ukuhlolwa kwe-alkaline phosphatase (ALP). I-ALP olunye uhlobo lwe-enzyme yesibindi. Kuvame ukusetshenziselwa ukusiza ukuxilonga ukuphazamiseka kwamathambo kanye nesifo sesibindi.

Amanye amagama: gamma-glutamyl transpeptidase, GGTP, Gamma-GT, GTP

Kusetshenziselwa ini?

Ukuhlolwa kwe-GGT kuvame ukusetshenziselwa:

• Siza ukuxilonga izifo zesibindi
• Thola ukuthi ukulimala kwesibindi kungenxa yesifo sesibindi noma ukuphazamiseka kwethambo
• Bheka ukuvinjelwa kwamapayipi enyongo
• Isikrini sokuqapha noma sokuqapha inkinga yokusetshenziswa kotshwala

Kungani ngidinga ukuhlolwa kwe-GGT?

Ungadinga ukuhlolwa kwe-GGT uma unezimpawu zesifo sesibindi. Izimpawu zifaka:

• Ukukhathala
• Ubuthakathaka
• I-jaundice, isimo esidala ukuthi isikhumba namehlo akho abe phuzi
• Ukuphelelwa isifiso sokudla
• Ubuhlungu besisu noma ukuvuvukala
• Isicanucanu nokuhlanza

Ungase futhi udinge lokhu kuhlolwa uma unemiphumela engavamile ekuhlolweni kwe-ALP kanye / noma kokunye ukuhlolwa kokusebenza kwesibindi.

Kwenzekani ngesikhathi sokuhlolwa kwe-GGT?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi amalungiselelo akhethekile wokuhlolwa kwe-GGT.

Ingabe zikhona izingozi ekuhlolweni kwe-GGT?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Uma imiphumela yakho ikhombisa ukuphakama kunamazinga ajwayelekile we-GGT, kungaba uphawu lokulimala kwesibindi. Umonakalo ungaba ngenxa yalezi zimo ezilandelayo:

• Isibindi
• Isifo sokuqina kwesibindi
• Ukuphazamiseka kokusebenzisa utshwala
• I-Pancreatitis
• Isifo sikashukela
• Ukwehluleka kwenhliziyo yokubopha
• Umphumela wecala lomuthi. Imithi ethile ingadala ukulimala kwesibindi kwabanye abantu.

Imiphumela ayikwazi ukukhombisa ukuthi unasiphi isimo, kodwa ingasiza ukukhombisa ukuthi ungakanani ukulimala kwesibindi onakho. Ngokuvamile, izinga eliphakeme le-GGT, liyanda izinga lokulimala kwesibindi.

Uma imiphumela yakho ikhombisa ukuthi unamazinga aphansi noma ajwayelekile e-GGT, kusho ukuthi mhlawumbe awunaso isifo sesibindi.

Imiphumela yakho ingaqhathaniswa nemiphumela yokuhlolwa kwe-ALP. Ukuhlolwa kwe-ALP kusiza ekutholeni ukuphazamiseka kwethambo. Ngokubambisana imiphumela yakho ingakhombisa okukodwa kokulandelayo:

• Amazinga aphezulu e-ALP namazinga aphezulu we-GGT kusho ukuthi izimpawu zakho kungenzeka ngenxa yokuphazamiseka kwesibindi futhi hhayi ukuphazamiseka kwethambo.
• Amazinga aphezulu e-ALP ne-GGT ephansi noma ejwayelekile kusho ukuthi kungenzeka ukuthi unenkinga yamathambo.

Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-GGT?

Ngaphezu kokuhlolwa kwe-ALP, umhlinzeki wakho anga-oda izivivinyo zomsebenzi wesibindi kanye noma ngemuva kokuhlolwa kwe-GGT. Lokhu kufaka phakathi:

• I-Alanine aminotransferase, noma i-ALT
• I-Aspartate aminotransferase, noma i-AST
• I-Lactic dehydrogenase, noma i-LDH

Izinkomba

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2. I-ClinLab Navigator [Inthanethi]. I-ClinLabNavigator; c2020. IGamma Glutamyltransferase; [kucashunwe ngo-2020 Eph 23]; [cishe izikrini ezi-2]. Kutholakala kusuka: http://www.clinlabnavigator.com/gamma-glutamyltransferase.html
3. UHinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Test. 2nd Ed, Kindle. IPhiladelphia: I-Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. IGamma Glutamyl Transferase; k. 314.
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5. IMayo Clinic Laboratories [i-Intanethi]. IMayo Foundation for Medical Education and Research; c1995-2020. I-ID Yokuhlola: GGT: Gamma-Glutamyltransferase, Serum: Clinical and Interpretive; [kucashunwe ngo-2020 Eph 23]; [cishe izikrini ezi-4]. Kutholakala kusuka: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/8677
6. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwegazi; [kucashunwe ngo-2020 Eph 23]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
7. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. IBile: Ukubuka konke; [kubuyekezwe ngo-2020 Eph 23; kucashunwe ngo-2020 Eph 23]; [cishe izikrini ezi-2]. Kutholakala ku: https://ufhealth.org/bile
8. Impilo ye-UF: University of Florida Health [Internet]. IGainesville (FL): Inyuvesi yaseFlorida Impilo; c2020. Ukuhlolwa kwegazi le-Gamma-glutamyl transferase (GGT): Ukubuka konke; [kubuyekezwe ngo-2020 Eph 23; kucashunwe ngo-2020 Eph 23]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://ufhealth.org/gamma-glutamyl-transferase-ggt-blood-test
9. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2020. I-Health Encyclopedia: IGamma-Glutamyl Transpeptidase; [kucashunwe ngo-2020 Eph 23]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=gamma_glutamyl_transpeptidase
10. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2020. Imininingwane Yezempilo: Ukuhlolwa Komsebenzi Wesibindi: Uhlolojikelele Lokuhlolwa; [kubuyekezwe ngo-2019 Dec 8; kucashunwe ngo-2020 Eph 23]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/testdetail/liver-function-tests/hw144350.html

Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.