Yini i-hemoglobin ene-glycated, iyini kanye nenani lesethenjwa

-Delile

• Yini i-hemoglobin eglycated
• Amanani ayizethenjwa

I-hemoglobin enomzimba, eyaziwa nangokuthi i-hemoglobin ye-glycosylated noma i-Hb1Ac, ukuhlolwa kwegazi okuhlose ukuhlola amazinga e-glucose ezinyangeni ezintathu ezedlule ngaphambi kokuba kwenziwe ukuhlolwa. Lokho kungenxa yokuthi i-glucose iyakwazi ukuhlala inamathele entweni eyodwa yeseli elibomvu, i-hemoglobin, kuwo wonke umjikelezo weseli elibomvu, elihlala cishe izinsuku eziyi-120.

Ngakho-ke, ukuhlolwa kwe-hemoglobin ene-glycated kuyacelwa ngudokotela ukukhomba isifo sikashukela, ukuqapha ukukhula kwaso noma ukuhlola ukuthi ukwelashwa kwalesi sifo kuyasebenza yini, kwenziwa ngokuhlaziywa kwesampula encane yegazi eqoqwe elabhoratri.

Yini i-hemoglobin eglycated

Ukuhlolwa kwe-hemoglobin ene-glycated kwenziwa ngenhloso yokuhlola amazinga e-glucose ezinyangeni ezedlule, kuwusizo ekutholeni isifo sikashukela. Ngaphezu kwalokho, esimweni sabantu asebethole ukuthi banesifo sikashukela, lokhu kuhlolwa kuyasiza ukuhlola ukuthi ngabe ukwelashwa kuyasebenza yini noma kwenziwa ngendlela efanele, ngoba uma kungenjalo, ushintsho emiphumeleni lungaqinisekiswa.

Ngaphezu kwalokho, lapho inani le-hemoglobin ene-glycated liphakeme kakhulu kunokujwayelekile okucatshangelwa ilabhorethri, maningi amathuba okuthi lowo muntu abe nezinkinga ezihlobene nesifo sikashukela, njengezinguquko zenhliziyo, i-renal noma i-neuronal, ngokwesibonelo. Bona ukuthi yiziphi izinkinga eziyinhloko zesifo sikashukela.

Lokhu kuhlolwa kufaneleke kakhulu kunokuzila ukudla i-glucose ukuthola ukuxilongwa kokuqala kwesifo sikashukela, ngoba ukuhlolwa kwe-glucose kungathonywa izinguquko kwimikhuba yokudla yakamuva, engamele amazinga kashukela ajikelezayo ezinyangeni ezimbalwa ezedlule. Ngakho-ke, kungenzeka ukuthi ngaphambi kokwenza ukuhlolwa kwe-glucose, umuntu abe nokudla okunempilo futhi anoshukela omncane, ukuze i-glucose yokuzila ibe ngamanani ajwayelekile, angahle angabonakalisi iqiniso lomuntu.

Ngakho-ke, ukuze kutholakale ukuxilongwa kwesifo sikashukela, ukuhlolwa kweshukela esheshayo, i-hemoglobin ene-glycated kanye / noma ukuhlolwa kokubekezelela i-glucose, i-TOTG, kuvame ukucelwa. Funda kabanzi mayelana nokuhlolwa okusiza ukuxilonga isifo sikashukela.

Amanani ayizethenjwa

Amanani ayizethenjwa we-hemoglobin ene-glycated angahluka ngokuya kwelabhorethri, kepha ngokujwayelekile amanani abhekiwe yile:

• Jwayelekile: I-Hb1Ac phakathi kuka-4.7% no-5.6%;
• Isandulela sikashukela: I-Hb1Ac phakathi kuka-5.7% no-6.4%;
• Isifo sikashukela: I-Hb1Ac engaphezulu kuka-6.5% ezivivinyweni ezimbili ezenziwe ngokuhlukile.

Ngaphezu kwalokho, kubantu asebevele batholakala benesifo sikashukela, amanani we-Hb1Ac aphakathi kuka-6.5% no-7.0% akhombisa ukuthi kukhona ukulawula okuhle kwalesi sifo. Ngakolunye uhlangothi, amanani angaphezu kwe-Hb1Ac ngenhla kwe-8% akhombisa ukuthi isifo sikashukela asilawulwa kahle, kunengozi enkulu yokuba nezinkinga kanye noshintsho ekwelashweni kuyadingeka.

Ukuhlolwa kwe-hemoglobin ene-glycated akudingi ukulungiswa, noma kunjalo, njengoba kuvame ukucelwa kanye nohlolo lwe-glucose lokuzila, kungadingeka ukuzila okungenani amahora ayi-8.