IMedullary Carcinoma Yesifuba

-Delile

• Ziyini izimpawu ze-medullary carcinoma yesifuba?
• Yini ebangela i-medullary carcinoma yesifuba?
• Yiziphi izinto ezinobungozi ze-medullary carcinoma?
• Yiziphi izinketho zokwelashwa ze-medullary carcinoma yesifuba?
• Ngabe i-medullary carcinoma yesifuba itholakala kanjani?
• Siyini isibikezelo se-medullary carcinoma yesifuba?
• Uyini umbono we-medullary carcinoma yesifuba?

Ukubuka konke

I-Medullary carcinoma yesifuba iyinhlayiyana ye-ductal carcinoma ehlaselayo. Luhlobo lomdlavuza webele oqala emapayipini obisi. Lo mdlavuza webele uqanjwa ngoba isimila sifana nengxenye yobuchopho obaziwa ngokuthi yi-medulla. IMedullary carcinoma yesifuba imelela amaphesenti alinganiselwa ku-3 kuya kwangu-5 awo wonke amacala anomdlavuza webele atholakala.

IMedullary carcinoma imvamisa mancane amathuba okusabalala kuma-lymph node futhi isabele kakhulu ekwelashweni kunezinhlobo ezivame kakhulu zomdlavuza webele. Ukuyithola ezigabeni zayo zokuqala kungathuthukisa ukubikezela futhi kunciphise isidingo sokwelashwa okwengeziwe ngaphandle kokususa isimila uqobo.

Ziyini izimpawu ze-medullary carcinoma yesifuba?

Kwesinye isikhathi i-medullary carcinoma ingadala izimpawu ezimbalwa. Owesifazane angaqala abone isigaxa esifubeni sakhe. I-Medullary carcinoma yesifuba ijwayele ukuhlukanisa amaseli omdlavuza ngokushesha. Ngakho-ke, abesifazane abaningi bangakhomba isisindo esifubeni sabo esingaba ngosayizi. Isigaxa sithambekele ekubeni sithambe futhi sibe nenyama, noma siqine lapho sithinta ngemingcele echaziwe. Ama-carcinomas amaningi ama-medullary angaphansi kwamasentimitha ama-2 ngosayizi.

Abanye besifazane bangathola ezinye izimpawu ezihlobene ne-medullary carcinoma, kufaka phakathi:

• isisa sebele
• ubuhlungu
• ububomvu
• ukuvuvukala

Uma uhlangabezana nanoma iyiphi yalezi zimpawu, kufanele ubone udokotela.

Yini ebangela i-medullary carcinoma yesifuba?

Ngokwesiko, izicubu zomdlavuza webele zingaba nethonya lamahomoni. IMedullary carcinoma yesifuba, noma kunjalo, imvamisa ayithonywanga yi-hormone. Esikhundleni salokho, owesifazane uthola ushintsho ekwakhekeni kofuzo kwamaseli asesifubeni sakhe. Lokhu kubangela ukuthi amangqamuzana akhule ngokungalawuleki (umdlavuza). Odokotela abazi ukuthi kungani lezi zinguquko zenzeka noma ukuthi zihlobene kanjani ne-medullary carcinoma yebele.

Yiziphi izinto ezinobungozi ze-medullary carcinoma?

Abanye besifazane abanokushintshwa kwezakhi zofuzo okwaziwa ngokuthi isakhi sofuzo i-BRCA-1 basengozini enkulu yokutholakala ukuthi bane-medullary carcinoma yesifuba, ngokusho kukaJohn Hopkins Medicine. Lolu hlobo luvame ukusebenza emindenini. Ngakho-ke, uma owesifazane enomlando wesifo somdlavuza webele emalungwini omndeni wakhe asondelene naye, usengozini enkulu yokuthola lesi sifo. Kodwa-ke, uma owesifazane enalesi sakhi, lokhu akusho ukuthi uzothola i-medullary carcinoma yebele.

Ukuxilongwa kwe-medullary carcinomas kuphakathi kweminyaka engama-45 nengama-52. Lokhu kuvame ukuba mncane kancane kunabesifazane abatholakala benama-medullary carcinomas, abatholakala beneminyaka engama-55 noma ngaphezulu.

Yiziphi izinketho zokwelashwa ze-medullary carcinoma yesifuba?

Udokotela angahlola izindlela ezahlukahlukene zokwelashwa ze-medullary carcinoma. Bazobheka ubukhulu besimila, uhlobo lweseli, nokuthi uma isimila sesisabalalele kuma-lymph node aseduze. Ngoba izimila ngokwesiko mancane amathuba okuthi zisabalale, abanye odokotela bancoma ukuthi basuse isimila kuphela futhi bangaphishekeli ezinye izindlela zokwelashwa. Lokhu kuyiqiniso lapho isimila “siyi-medullary emsulwa” futhi sinamaseli kuphela afana ne-medullary carcinoma.

Kodwa-ke, udokotela futhi angancoma ukususwa kwesimila kanye nezinye izinhlobo zokwelashwa komdlavuza. Lokhu kuyiqiniso lapho umdlavuza ungaba “nezimpawu zemiduli.” Lokhu kusho ukuthi amanye amaseli abukeka njenge-medullary carcinoma lapho amanye abukeka njenge-ductal cell carcinoma engenayo. Udokotela futhi angancoma ukwelashwa okwengeziwe uma umdlavuza ususakazekele kuma-lymph node. Lezi zindlela zokwelapha zingabandakanya i-chemotherapy (imithi yokubulala amaseli akhula ngokushesha) noma imisebe.

Eminye imithi ngokwesiko esetshenziselwa ukwelapha umdlavuza webele ayisebenzi kahle kwi-medullary carcinoma yesifuba. Lokhu kufaka phakathi izindlela zokwelapha ezihlobene ne-hormone ezifana ne-tamoxifen noma i-aromatase inhibitors. Imidlavuza eminingi yamabele e-medullary ingumdlavuza "ongenayo kathathu". Lokhu kusho ukuthi umdlavuza awuphenduli kuma-hormone progesterone kanye / noma i-estrogen noma enye iphrotheni eyaziwa njenge-HER2 / neu protein.

Ngabe i-medullary carcinoma yesifuba itholakala kanjani?

Ngoba i-medullary carcinoma yesifuba ayivamile kakhulu, odokotela bangaba nesikhathi esinzima ekuqaleni ukuthola uhlobo oluthile lomdlavuza. Bangakhomba isilonda sesifuba ku-mammogram, okuwuhlobo olukhethekile lokucabanga nge-X-ray okusetshenziselwa ukuhlola isifuba. Isilonda sivame ukuba yindilinga noma sime okweqanda futhi asinamamaki achazwe kahle. Udokotela futhi anga-oda ezinye izifundo zokuthwebula izithombe. Lokhu kungafaka ukuskena kwe-ultrasound noma ukuskena kwe-magnetic resonance imaging (MRI).

I-Medullary carcinomas yesifuba ingahlukahluka ukuxilonga. Kwesinye isikhathi, owesifazane angaba sethubeni lokuthola isifo somdlavuza ngokuzizwa, kunalokho okungabonakala ocwaningweni lwezithombe. Ngalesi sizathu, kubalulekile ukuthi owesifazane azihlole njalo ngenyanga amabele akhe, lapho ezwa khona ukuthi izicubu zakhe zamabele nezingono zezigaxa.

Uma udokotela ekhomba isigaxa ngokuthinta noma ngokuthatha isithombe, bangancoma ukuhlolwa kwesigaxa. Lokhu kubandakanya ukususa amaseli noma isigaxa uqobo ukuze sihlolwe. Udokotela ogxile ekuhloleni amangqamuzana ngokungajwayelekile waziwa njenge-pathologist. Isazi sezifo sizohlola amangqamuzana ngaphansi kwesibonakhulu. Amaseli omdlavuza weMedullary nawo ajwayele ukuba nokuguquka kofuzo okungu-p53. Ukuvivinywa kwalokhu kuguquka kungaxhasa ukwesekwa kwe-medullary carcinoma, noma kungewona wonke umdlavuza we-medullary onoguquko lwe-p53.

Siyini isibikezelo se-medullary carcinoma yesifuba?

Izilinganiso zeminyaka emihlanu zokusinda kwe-medullary carcinoma yesifuba zivame ukuba kuphi ukusuka kuma-89 kuye kuma-95 amaphesenti. Lokhu kusho ukuthi eminyakeni emihlanu ngemuva kokuxilongwa, noma yikuphi kusuka kumaphesenti angama-89 kuya kwangama-95 abesifazane abanalolu hlobo lomdlavuza abasaphila.

Uyini umbono we-medullary carcinoma yesifuba?

I-Medullary carcinoma yesifuba ivame ukuphendula kangcono ekwelashweni komdlavuza webele kunezinye izinhlobo zama-carcinomas e-ductal ahlaselayo. Ngokutholwa nokwelashwa kusenesikhathi, izibikezelo kanye namazinga okusinda ayathandeka.