I-Myalept yokwelapha i-lipodystrophy

-Delile

• Izinkomba zeMyalept
• Ungayisebenzisa kanjani iMyalept
• Imiphumela emibi ye-Myalept
• Ukungafani kweMyalept
• Bona ukuthi ukwelashwa kwalolu hlobo nezifo kufanele kube kanjani:

I-Myalept ngumuthi oqukethe uhlobo lokufakelwa lwe-leptin, i-hormone ekhiqizwa ngamaseli anamafutha futhi esebenza ohlelweni lwezinzwa olulawula imizwa yendlala kanye ne-metabolism, ngakho-ke isetshenziselwa ukwelapha imiphumela ezigulini ezinamafutha amancane, icala le-lipodystrophy yokuzalwa, ngokwesibonelo.

I-Myalept iqukethe i-metreleptin ekubunjweni kwayo futhi ingathengwa e-United States ngesidakamizwa, ngesimo somjovo ongaphansi, ofana nezibaya ze-insulin.

Izinkomba zeMyalept

I-Myalept ikhonjiswa njengokwelashwa okushintshwayo ezigulini ezinezinkinga ezibangelwa ukuntuleka kwe-leptin, njengasesimweni sokutholwa noma kokuzalwa kwe-lipodystrophy jikelele.

Ungayisebenzisa kanjani iMyalept

Indlela yokusebenzisa iMyalept iyehluka ngokuya ngesisindo sesiguli nocansi, futhi imihlahlandlela ejwayelekile ifaka phakathi:

• Isisindo somzimba esingama-40 kg noma ngaphansi: umthamo wokuqala ka-0.06 mg / kg / ngosuku, ongakhuphuka ufike kubukhulu obungu-0.13 mg / kg / ngosuku;
• Amadoda angaphezu kwama-40 kg: umthamo wokuqala we-2.5 mg / kg / ngosuku, ongakhuphuka ube ngu-10 mg / kg / ngosuku;
• Abesifazane abangaphezu kwama-40 kg: umthamo wokuqala we-5 mg / kg / ngosuku, ongakhuphuka ufike ku-10 mg / kg / ngosuku.

Ngakho-ke, umthamo weMyalept kufanele ukhonjiswe njalo ngudokotela we-endocrinologist. IMyalept inikezwa ngomjovo ngaphansi kwesikhumba, ngakho-ke kubalulekile ukuthola ukwelulekwa ngudokotela noma umhlengikazi ngokuthi ungawusebenzisa kanjani umjovo.

Imiphumela emibi ye-Myalept

Imiphumela emibi ye-Myalept ifaka ikhanda, ukwehla kwesisindo, ubuhlungu besisu kanye namazinga eshukela anciphile egazini, angadala ukukhathala okulula, isiyezi nokujuluka okubandayo.

Ukungafani kweMyalept

IMyalept iyaphikiswa ezigulini ezinesisindo sokukhuluphala ezingahlobene nokushoda kwe-leptin yokuzalwa noma nge-hypersensitivity to metreleptin.

Bona ukuthi ukwelashwa kwalolu hlobo nezifo kufanele kube kanjani:

• Ungayelapha kanjani i-lipodystrophy yokuzalwa evamile