UPemphigus Foliaceus

-Delile

• Ziyini izimpawu?
• Ziyini izimbangela?
• Yiziphi izinketho zokwelashwa?
• Yiziphi izinkinga?
• Ukubonana nodokotela nini
• Umbono

Ukubuka konke

I-Pemphigus foliaceus yisifo sokuzilimaza esibangela amabhamuza alumayo ukuba akhe esikhunjeni sakho. Iyingxenye yomndeni wezimo zesikhumba ezingandile ezibizwa ngokuthi i-pemphigus ekhiqiza amabhamuza noma izilonda esikhumbeni, emlonyeni, noma esithweni sangasese.

Kunezinhlobo ezimbili eziyinhloko ze-pemphigus:

• pemphigus vulgaris
• pemphigus foliaceus

I-Pemphigus vulgaris uhlobo oluvame kakhulu futhi olunzima kakhulu. I-Pemphigus vulgaris ayithinti nje kuphela isikhumba, kodwa futhi nolwelwesi lwamafinyila. Kubangela amabhamuza abuhlungu ukwakheka emlonyeni wakho, esikhumbeni sakho nasesithweni sakho sangasese.

I-Pemphigus foliaceus ibangela ukuthi kube namabhamuza amancane esifubeni nasebusweni. Imnene kune-pemphigus vulgaris.

I-Pemphigus erythematosus uhlobo lwe-pemphigus foliaceus olwenza ukuthi amabhamuza akhe ebusweni kuphela. Ithinta abantu abane-lupus.

Ziyini izimpawu?

I-Pemphigus foliaceus ibangela amabhamuza agcwele uketshezi esikhunjeni sakho, imvamisa esifubeni sakho, emuva nasemahlombe. Ekuqaleni amabhamuza mancane, kepha akhula kancane kancane futhi ande isibalo. Ekugcineni bangakwazi ukumboza isifuba sakho sonke, ubuso nobuso.

Amabhamuza aqhekeka kalula. Uketshezi lungaphuma kubo. Uma uhlikihla isikhumba sakho, lonke ungqimba oluphezulu lungahlukana nolwangezansi kamuva bese luyaxebuka eshidini.

Ngemuva kokuthi amabhamuza evuleke, angakha izilonda. Izilonda zikala futhi ziqhume ngaphezulu.

Yize i-pemphigus foliaceus ngokuvamile ingebuhlungu, ungezwa ubuhlungu noma umuzwa ovuthayo endaweni yamabhalbhu. Amabhamuza nawo angase alume.

Ziyini izimbangela?

I-Pemphigus foliaceus yisifo esizimele. Imvamisa amasosha omzimba akhipha amaprotheni abizwa ngama-antibody ukulwa nabahlaseli bakwamanye amazwe njengamagciwane namagciwane. Kubantu abanesifo esizimele, amasosha omzimba ngephutha alandela izicubu zomzimba uqobo.

Uma une-pemphigus foliaceus, amasosha omzimba abopha iphrotheni engxenyeni engaphandle yesikhumba sakho, ebizwa nge- epidermis. Kulolu ungqimba lwesikhumba kunamaseli abizwa ngama-keratinocyte. Lawa maseli akhiqiza amaprotheni - i-keratin - enikeza ukwakheka nokwesekwa esikhunjeni sakho. Lapho ama-antibody ehlasela ama-keratinocyte, ayahlukana.Uketshezi kugcwalisa izikhala abazishiya ngemuva. Lolu ketshezi lwakha amabhamuza.

Odokotela abazi ukuthi yini ebangela i-pemphigus foliaceus. Izici ezimbalwa zingakhuphula amathuba okuthola lesi simo, kufaka phakathi:

• ukuba namalungu omndeni ane-pemphigus foliaceus
• ukuvezwa yilanga
• ukuthola ukulunywa yisinambuzane (emazweni aseNingizimu Melika)

Izidakamizwa eziningana ziye zaxhunyaniswa ne-pemphigus foliaceus, kufaka phakathi:

• i-penicillamine (Cuprimine), esetshenziselwa ukwelapha isifo sikaWilson
• i-angiotensin iguqula ama-enzyme inhibitors afana ne-captopril (Capoten) ne-enalapril (Vasotec), esetshenziselwa ukwelapha umfutho wegazi ophezulu
• ama-angiotensin-II receptor blockers anjenge-candesartan (Atacand), asetshenziselwa ukwelapha umfutho wegazi ophezulu
• ama-antibiotic afana ne-rifampicin (Rifadin), asetshenziselwa ukwelapha izifo ezibangelwa amagciwane
• izidakamizwa ezingezona ukuvuvukala (ama-NSAID)

I-Pemphigus foliaceus ingaqala nganoma yisiphi isikhathi, kepha ivame ukuthinta abantu abaneminyaka engama-50 kuya kwengama-60. Abantu abangamagugu amaJuda basengozini enkulu ye-pemphigus vulgaris.

Yiziphi izinketho zokwelashwa?

Inhloso yokwelashwa ukususa amabhamuza bese uphulukisa amabhamuza osuvele unawo. Udokotela wakho angakunikeza ukhilimu noma amaphilisi e-corticosteroid. Lo muthi wehlisa ukuvuvukala emzimbeni wakho. Ukweqiwa okuphezulu kwama-corticosteroids kungadala imiphumela emibi njengokukhuphuka kwamazinga kashukela egazini, ukuzuza kwesisindo, nokulahleka kwamathambo.

Ezinye izidakamizwa ezisetshenziselwa ukwelapha i-pemphigus foliaceus zifaka:

• Ukucindezela ama-immune. Izidakamizwa ezifana ne-azathioprine (Imuran) ne-mycophenolate mofetil (CellCept) zivikela amasosha akho omzimba ekuhlaseleni izicubu zomzimba wakho. Umphumela oyinhloko ovela kule mithi yingozi eyengeziwe yokutheleleka.
• Imithi elwa namagciwane, imishanguzo yokulwa namagciwane, nemithi yokubulala amagciwane. Lokhu kungavimbela ukuthi amabhamuza angatheleleki uma eqhamuka evulekile.

Uma amabhamuza emboza isikhumba sakho esiningi, kungadingeka ukuthi uhlale esibhedlela ukuze uthole ukwelashwa. Odokotela nabahlengikazi bazokuhlanza futhi babophe izilonda zakho ukuvimbela ukutheleleka. Ungathola uketshezi ukufaka esikhundleni salokho okulahlekele ezilondeni.

Yiziphi izinkinga?

Amabhamuza avulekayo angatheleleka ngamagciwane. Uma amabhaktheriya angena egazini lakho, angadala ukutheleleka okusongela impilo okubizwa nge-sepsis.

Ukubonana nodokotela nini

Bheka udokotela wakho uma unamabhamuza esikhunjeni sakho, ikakhulukazi uma evuleka.

Udokotela wakho uzokubuza ngezimpawu zakho bese ehlola isikhumba sakho. Bangasusa ucezu lwesicubu ku-blister bese beluthumela ebhodini lokuhlola. Lokhu kubizwa ngokuthi yi-biopsy yesikhumba.

Ungase futhi uhlolwe igazi ukuze ubheke amasosha omzimba akhiqizwa amasosha akho omzimba lapho une-pemphigus foliaceus.

Uma usuvele utholakale une-pemphigus vele, kufanele uxhumane nodokotela wakho uma uthuthuka:

• amabhamuza amasha noma izilonda
• ukusabalala okusheshayo kwenani lezilonda
• imfiva
• ububomvu noma ukuvuvukala
• Ukugodola
• ubuthakathaka noma imisipha ebuhlungu noma amalunga

Umbono

Abanye abantu baba ngcono ngaphandle kokwelashwa. Abanye bangahlala nalesi sifo iminyaka eminingi. Ungahle udinge ukuthatha umuthi iminyaka ukuvikela amabhamuza ukuthi angabuyi.

Uma umuthi ubangele i-pemphigus foliaceus, ukumisa umuthi kuvame ukusikhipha lesi sifo.