Ukuhlolwa kwePorphyrin

-Delile

• Yini ukuhlolwa kwe-porphyrin?
• Zisetshenziselwani?
• Kungani ngidinga ukuhlolwa kwe-porphyrin?
• Kwenzekani ngesikhathi sokuhlolwa kwe-porphyrin?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi ekuhlolweni kwe-porphyrin?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-porphyrin?
• Izinkomba

Yini ukuhlolwa kwe-porphyrin?

Ukuhlolwa kwe-Porphyrin kukala izinga lama-porphyrins egazini lakho, emchameni noma esitokisini. Ama-Porphyrins amakhemikhali asiza ukwenza i-hemoglobin, uhlobo lwamaprotheni kumaseli akho abomvu egazi. IHemoglobin ithwala umoya-mpilo ovela emaphashini wakho uye kuwo wonke umzimba wakho.

Kuyinto evamile ukuba nenani elincane lama-porphyrin egazini lakho nakwezinye iziphuzo zomzimba. Kepha i-porphyrin eningi kakhulu ingasho ukuthi unohlobo lwe-porphyria. I-Porphyria yisifo esingajwayelekile esingadala izinkinga ezinkulu zempilo. I-Porphyria ivame ukuhlukaniswa ngezigaba ezimbili:

• Ama-porphyrias acute, okuthinta kakhulu uhlelo lwezinzwa futhi ibangele izimpawu zesisu
• Ama-porphyrias ahlukanisiwe, ezidala izimpawu zesikhumba lapho uvezwa yilanga

Amanye ama-porphyrias athinta kokubili isimiso sezinzwa nesikhumba.

Amanye amagama: protoporphyrin; i-protoporphyrin, igazi; protoporhyrin, isihlalo; ama-porphyrins, indle; i-uroporphyrin; ama-porphyrins, umchamo; Ukuhlolwa kweMauzerall-Granick; i-asidi; ALA; i-porphobilinogen; I-PBG; i-erythrocyte protoporphyrin yamahhala; ama-porphyrins ahlukanisiwe erythrocyte; FEP

Zisetshenziselwani?

Ukuhlolwa kwe-Porphyrin kusetshenziselwa ukuxilonga noma ukuqapha i-porphyria.

Kungani ngidinga ukuhlolwa kwe-porphyrin?

Ungadinga ukuhlolwa kwe-porphyrin uma unezimpawu ze-porphyria. Kunezimpawu ezahlukahlukene zezinhlobo ezahlukahlukene ze-porphyria.

Izimpawu ze-acute porphyria zifaka:

• Ubuhlungu besisu
• Ukuqunjelwa
• Isicanucanu nokuhlanza
• Umchamo obomvu noma onsundu
• Ukulinganisa noma ubuhlungu ezandleni kanye / noma ezinyaweni
• Ubuthakathaka bemisipha
• Ukudideka
• Ukusangana

Izimpawu ze-porphyria ezinqunyiwe zifaka:

• Ukuzwela ngokweqile ekukhanyeni kwelanga
• Amabhamuza esikhunjeni avele elangeni
• Ububomvu nokuvuvukala esikhunjeni esivele obala
• Ukulunywa
• Izinguquko kumbala wesikhumba

Ungadinga futhi ukuhlolwa kwe-porphyrin uma othile emndenini wakho ene-porphyria. Izinhlobo eziningi ze-porphyria zizuzwe njengefa, okusho ukuthi isimo sidluliselwa sisuka kumzali siye enganeni.

Kwenzekani ngesikhathi sokuhlolwa kwe-porphyrin?

Ama-Porphyrins angahlolwa egazini, emchameni noma esitokisini. Izinhlobo ezivame kakhulu zokuhlolwa kwe-porphyrin zibhalwe ngezansi.

• Ukuhlolwa Kwegazi
  • Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.
• Isampula le-24-Hour Urine
  • Uzoqoqa wonke umchamo wakho ngesikhathi samahora angama-24. Kulesi sivivinyo, umhlinzeki wakho wezokunakekelwa kwempilo noma ilabhorethri uzokunikeza isitsha kanye nemiyalelo ethile yokuthi uwalanda kanjani amasampuli akho ekhaya. Qiniseka ukuthi ulandela yonke imiyalelo ngokucophelela. Lokhu kuhlolwa kwesampula yamahora angama-24 kusetshenziswa ngoba inani lezinto ezisemchameni, kufaka phakathi i-porphyrin, lingahluka usuku lonke. Ngakho-ke ukuqoqa amasampula amaningi ngosuku kunganikeza isithombe esinembe kakhudlwana kokuqukethwe umchamo wakho.
• Ukuhlolwa okungahleliwe komchamo
  • Unganikeza isampula yakho nganoma yisiphi isikhathi sosuku, ngaphandle kwamalungiselelo akhethekile noma ukuphatha okudingekayo. Lokhu kuhlolwa kuvame ukwenziwa ehhovisi lomhlinzeki wezempilo noma elebhu.
• I-Stool Test (ebizwa nangokuthi i-protoporphyrin esitokisini)
  • Uzoqoqa isampula yendle yakho bese uyifaka esitsheni esikhethekile. Umhlinzeki wakho wokunakekelwa kwezempilo uzokunikeza imiyalo yokuthi ungasilungisa kanjani isampula sakho bese usithumela elebhu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi noma yimaphi amalungiselelo akhethekile wokuhlolwa kwegazi noma umchamo.

Ukuhlolwa kwendle, ungatshelwa ukuthi ungadli inyama noma uthathe noma yimiphi imithi equkethe ama-aspirin izinsuku ezintathu ngaphambi kokuhlolwa kwakho.

Ingabe zikhona izingozi ekuhlolweni kwe-porphyrin?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Azikho izingozi ezaziwayo ekuhlolweni komchamo noma kwendle.

Isho ukuthini imiphumela?

Uma amazinga aphezulu e-porphyrin atholakala egazini lakho, emchameni, noma esitokisini, umhlinzeki wakho wezokunakekelwa kwempilo uzo-oda izivivinyo eziningi ukuqinisekisa ukuxilongwa nokuthola ukuthi unhloboni ye-porphyria. Ngenkathi lungekho ikhambi le-porphyria, isimo singalawulwa. Izinguquko ezithile zendlela yokuphila kanye / noma imishanguzo ingasiza ekuvikeleni izimpawu nezinkinga zesifo. Ukwelashwa okuqondile kuya ngohlobo lwe-porphyria onayo. Uma unemibuzo ngemiphumela yakho noma nge-porphyria, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa kwe-porphyrin?

Ngenkathi izinhlobo eziningi ze-porphyria zizuzwe njengefa, ezinye izinhlobo ze-porphyria nazo zingatholakala. I-porphyria etholakalayo ingadalwa yizinto ezahlukahlukene, kufaka phakathi ukuvezwa ngokweqile ekuholeni, i-HIV, i-hepatitis C, ukusebenzisa kakhulu i-iron, kanye / noma ukusetshenziswa kotshwala obunzima.

Izinkomba

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Imininingwane ekulesi siza akufanele isetshenziswe esikhundleni sezokunakekelwa kwezokwelapha noma iseluleko. Xhumana nomhlinzeki wezempilo uma unemibuzo ngempilo yakho.