I-Propafenone

-Delile

• Izinkomba zePropafenone
• Inani lePropafenone
• Imiphumela emibi ye-Propafenone
• Ukungafani kwePropafenone
• Ungayisebenzisa kanjani iPropafenone

I-Propafenone iyinto esebenzayo kumuthi we-antiarrhythmic owaziwa ngokuthengisa njengeRitmonorm.

Le mithi yokusetshenziswa komlomo nokujova ikhonjiswa ekwelapheni i-arrhythmias yenhliziyo, isenzo sayo sinciphisa ukujabula, ijubane lokuqhuba kwenhliziyo, ukugcina ukushaya kwenhliziyo kuzinzile.

Izinkomba zePropafenone

I-ventricular arrhythmia; i-arrhythmia engaphezulu.

Inani lePropafenone

Ibhokisi lika-300 mg lePropafenone eliqukethe amaphilisi angama-20 libiza cishe ama-reais angama-54 kanti ibhokisi lemithi engu-300 mg eliqukethe amaphilisi angama-30 libiza cishe ama-reais angama-81.

Imiphumela emibi ye-Propafenone

Ukuhlanza; isicanucanu; isiyezi; i-lupus-like syndrome; ukuvuvukala; angioneurotic.

Ukungafani kwePropafenone

Ingozi Yokukhulelwa C; ukuncelisa ibele; i-asthma noma i-bronchospasm engeyona iguliswa njenge-emphysema noma i-bronchitis engapheli (ingahle ibe yimbi kakhulu); ibhulokhi ye-atrioventricular; sinus bradycardia; ukushaqeka kwe-cardiogenic noma i-hypotension enamandla (ingahle ibe yimbi kakhulu); ukwehluleka kokulawula inhliziyo okungalawuleki (kungahle kube kubi kakhulu); i-sinus node syndrome; ukuphazamiseka kokulinganisela kwe-electrolyte (imiphumela ye-pro-arrhythmic ye-propafenone ingathuthukiswa); iziyaluyalu esezivele zikhona ekuqhutshweni kwenhliziyo (i-atrio-ventricular, intraventricular kanye ne-syncatrial) ezigulini ezingasebenzisi i-pacemaker.

Ungayisebenzisa kanjani iPropafenone

Ukusetshenziswa ngomlomo

Abantu abadala abanesisindo esingaphezu kwama-70 kg

• Qala ngo-150 mg njalo emahoreni ayisishiyagalombili; uma kunesidingo, khuphuka (emva kwezinsuku ezi-3 kuye kwezi-4) uye kuma-300 mg, kabili ngosuku (njalo ngamahora ayi-12).

Umkhawulo wesilinganiso sabantu abadala: 900 mg ngosuku.

Iziguli ezinesisindo esingaphansi kwama-70 kg

• Kufanele banciphise imithamo yabo yansuku zonke.

Asebekhulile noma Iziguli ezinokulimala okukhulu kwenhliziyo

• Kufanele bathole umkhiqizo ngamanani akhuphukayo, ngesikhathi sokuqala kokulungiswa.

Ukusetshenziswa ngomjovo

Abantu abadala

• Isicelo esiphuthumayo: 1 kuya ku-2 mg ngekhilogremu yesisindo somzimba, ngomzila oqondile we-intravenous, ofakwa kancane (kusuka emizuzwini emi-3 kuye kwemi-5). Sebenzisa umthamo wesi-2 kuphela ngemuva kwemizuzu engama-90 kuye kwengu-120 (ngokufakwa emthanjeni, ngehora elingu-1 ukuya kwele-3).

Isondlo: 560 mg emahoreni angama-24 (70 mg njalo emahoreni ama-3); isimo esibucayi siphelile: sebenzisa ithebhulethi ye-profenanone (300 mg njalo emahoreni ayi-12).