Yini Ebangela iTransaminitis?

-Delile

• Izimbangela ezivamile ze-transaminitis
• Isifo sesibindi esinamafutha
• I-hepatitis yegciwane
• Imithi, izithasiselo, namakhambi
• Izimbangela ezingavamile kakhulu ze-transaminitis
• I-HELLP syndrome
• Izifo zofuzo
• I-hepatitis engeyona igciwane
• Ukutheleleka ngegciwane
• Okubalulekile

Kuyini i-transaminitis?

Isibindi sakho sidiliza izakhi zomzimba bese sihlunga ubuthi emzimbeni wakho, lokho sikwenza ngosizo lwama-enzyme. I-Transaminitis, kwesinye isikhathi ibizwa ngokuthi yi-hypertransaminasemia, ibhekisa ekubeni namazinga aphezulu ama-enzyme athile wesibindi okuthiwa ama-transaminases. Uma unama-enzyme amaningi esibindini sakho, aqala ukuhambisa ekusakazeni kwegazi lakho. I-Alanine transaminase (ALT) ne-aspartate transaminase (AST) yizona transaminase ezimbili ezivame kakhulu ezithinteka ku-transaminitis.

Iningi labantu abane-transaminitis abazi ukuthi banalo kuze kube benza ukuhlolwa kwesibindi. I-Transaminitis uqobo ayivezi zimpawu, kepha imvamisa ikhombisa ukuthi kukhona okunye okwenzekayo, ngakho odokotela bakusebenzisa njengethuluzi lokuxilonga. Abanye abantu banamazinga aphezulu okwesikhashana ama-enzyme wesibindi ngaphandle kwesizathu esiyimbangela. Kodwa-ke, ngoba i-transaminitis ingakwazi ngophawu lwezimo ezinzima, njengesifo sesibindi noma i-hepatitis, kubalulekile ukukhipha noma yiziphi izimbangela ezingaba khona.

Izimbangela ezivamile ze-transaminitis

Isifo sesibindi esinamafutha

Isibindi sakho ngokwemvelo siqukethe amanoni, kepha amaningi awo angaholela ezifweni zesibindi ezinamafutha. Imvamisa kuhlotshaniswa nokuphuza utshwala obuningi, kepha isifo sesibindi esinamafutha angenalo utshwala siyanda kakhulu. Akekho onesiqiniseko sokuthi yini ngempela ebangela isifo sesibindi esinamafutha angenalo utshwala, kodwa izici ezivamile zobungozi zifaka:

• ukukhuluphala ngokweqile
• cholesterol ephezulu

Isifo esinamafutha sesibindi imvamisa asibangeli zimpawu, futhi abantu abaningi abazi ukuthi banaso baze bahlole igazi. Kodwa-ke, abanye abantu banokukhathala, ubuhlungu besisu obumnene, noma isibindi esikhulisiwe udokotela wakho angasizwa ngesikhathi sokuhlolwa komzimba. Ukwelapha isifo sesibindi esinamafutha kuvame ukufaka ukuguquka kwendlela yokuphila, njengokugwema utshwala, ukugcina isisindo esinempilo, nokudla ukudla okunomsoco.

I-hepatitis yegciwane

I-hepatitis isho ukuvuvukala kwesibindi. Kunezinhlobo eziningana zesifo sokusha kwesibindi kohlobo, kodwa esivame kakhulu i-hepatitis yegciwane. Izinhlobo ezivame kakhulu ze-hepatitis yegciwane elibanga i-transaminitis yi-hepatitis B ne-hepatitis C.

I-Hepatitis B no-C babelana ngezimpawu ezifanayo, ezibandakanya:

• isikhumba namehlo anombala ophuzi, okuthiwa i-jaundice
• umchamo omnyama
• isicanucanu nokuhlanza
• ukukhathala
• ubuhlungu besisu noma ukungaphatheki kahle
• Ubuhlungu bamalunga nemisipha
• imfiva
• ukulahlekelwa isifiso sokudla

Khuluma nodokotela wakho uma unezimpawu ze-hepatitis yegciwane. Uma ishiywe ingalashwa, ingadala ukulimala kwesibindi unomphela, ikakhulukazi uma une-hepatitis C.

Imithi, izithasiselo, namakhambi

Ngaphezu kokusiza umzimba wakho ukucubungula ukudla, isibindi sakho siphinda sidilize noma yini enye oyithatha ngomlomo, kufaka phakathi imishanguzo, izithasiselo namakhambi. Kwesinye isikhathi lokhu kungadala i-transaminitis, ikakhulukazi lapho ithathwa ngemithamo ephezulu.

Imithi engadala i-transaminitis ifaka:

• imishanguzo yezinhlungu ezingekho emthethweni, njenge-acetaminophen (iTylenol) noma ibuprofen (Advil, Motrin)
• izitatimende, njenge-atorvastatin (Lipitor) ne-lovastatin (Mevacor, Altocor)
• imishanguzo yenhliziyo, efana ne-amiodarone (Cordarone) ne-hydralazine (i-Apresoline)
• ama-anti-depressants e-cyclic, njenge-desipramine (Norpramin) ne-Imipramine (Tofranil)

Izithasiselo ezingadala i-transaminitis zifaka:

• uvithamini A

Amakhambi ajwayelekile angadala i-transaminitis afaka:

• isahluko
• kava
• senna
• ukhakhayi
• ephedra

Uma uthatha noma yikuphi kwalokhu, tshela udokotela wakho nganoma yiziphi izimpawu ezingavamile onazo. Ungase futhi ufune ukuhlolwa kwegazi lakho njalo ukuze uqiniseke ukuthi alithinti isibindi sakho. Uma kunjalo, kungenzeka ukuthi udinga nje ukwehlisa inani olithathayo.

Izimbangela ezingavamile kakhulu ze-transaminitis

I-HELLP syndrome

I-HELLP syndrome yisimo esibi esiphatha amaphesenti ama-5-8 okukhulelwa. Kushiwo iqembu lezimpawu ezibandakanya:

• Hukuvela
• U-EL: ama-enzyme wesibindi aphakeme
• I-LP: ukubalwa kweplatelet okuphansi

Kuvame ukuhlotshaniswa ne-preeclampsia, edala umfutho wegazi ophezulu kwabesifazane abakhulelwe. I-HELLP syndrome ingadala ukulimala kwesibindi, izinkinga zokopha, ngisho nokufa uma ingalawulwa kahle.

Izimpawu ezingeziwe ze-HELLP syndrome zifaka:

• ukukhathala
• ubuhlungu besisu
• isicanucanu nokuhlanza
• ubuhlungu besisu
• ubuhlungu behlombe
• ubuhlungu lapho uphefumula ngokujulile
• ukopha
• ukuvuvukala
• izinguquko embonweni

Uma ukhulelwe futhi uqala ukubona noma iyiphi yalezi zimpawu, xhumana nodokotela wakho ngokushesha okukhulu.

Izifo zofuzo

Izifo eziningi ezizuzwe njengefa zingadala i-transaminitis. Ngokuvamile ziyizimo ezithinta izinqubo zomzimba wakho zomzimba.

Izifo zofuzo ezingadala i-transaminitis zifaka:

• hemochromatosis
• isifo se-celiac
• Isifo sikaWilson
• i-alpha-antitrypsin ukuntula

I-hepatitis engeyona igciwane

I-autoimmune hepatitis kanye ne-hepatitis enotshwala yizinhlobo ezimbili ezivamile zesifo sokusha kwesibindi esingesona igciwane ezingadala i-transaminitis. I-hepatitis engeyona igciwane ikhiqiza izimpawu ezifanayo ne-hepatitis yegciwane.

I-autoimmune hepatitis yenzeka lapho amasosha akho omzimba ehlasela amangqamuzana esibindi sakho. Abaphenyi abaqiniseki ukuthi yini ebangela lokhu, kodwa izici zofuzo nezemvelo zibonakala zidlala indima.

Isifo sokusha kwesibindi esidakayo siphumela ekuphuzeni utshwala obuningi, imvamisa ngokuhamba kweminyaka eminingi. Uma une-hepatitis enotshwala, kufanele uyeke ukuphuza utshwala. Ukungakwenzi lokho kungaholela ezinkingeni ezinkulu, ezihlanganisa nokufa.

Ukutheleleka ngegciwane

Ukutheleleka okuvame kakhulu kwegciwane okubangela i-transaminitis kungukutheleleka nge-mononucleosis kanye ne-cytomegalovirus (CMV).

I-mononucleosis esithathelwanayo isakazeka ngamathe futhi ingadala:

• amalaka okuvuvukala nama-lymph node
• Umphimbo obuhlungu
• imfiva
• ukuvuvukala ubende
• ikhanda
• imfiva

Ukutheleleka nge-CMV kuvame kakhulu futhi kungasakazeka ngoketshezi oluningi lomzimba, kufaka phakathi amathe, igazi, umchamo, isidoda nobisi lwebele. Iningi labantu alizitholi izimpawu ngaphandle kokuthi linamasosha omzimba abuthakathaka. Lapho ukutheleleka kwe-CMV kudala izimpawu, kuvame ukufana nalokho kwe-mononucleosis esithathelwanayo.

Okubalulekile

Izinto ezahlukahlukene, kusuka ezifweni ezimbi ukuya ekushintsheni kwemithi elula, kungadala ama-enzyme wesibindi aphakeme, aziwa nge-transaminitis. Akuvamile futhi ukuthi abanye abantu babe nama-enzyme wesibindi andile okwesikhashana. Uma ukuhlolwa kwegazi kukhombisa ukuthi une-transaminitis, kubalulekile ukusebenzisana nodokotela wakho ukukhipha noma yiziphi izimbangela ezingaba yimbangela ngoba eziningi zazo zingaholela ekulimaleni okukhulu kwesibindi ngisho nasekuhlulekeni kwesibindi uma zingalashwa.