Ukwelashwa Kwe-Asthma Eosinophilic

-Delile

• I-corticosteroids emuncwe nangomlomo
• Izinguquko zeLeukotriene
• I-Biologics
• Ama-inhalers wokutakula
• Ama-anticholinergics
• Ukuthatha

I-asthma ye-eosinophilic iyi-subtype ye-asthma evame ukukhula kamuva empilweni. Isilinganiso seminyaka yokuqala siphakathi kweminyaka engama-35 nengama-50 ubudala. Kungakhula kubantu abangazange batholwe ngaphambilini ukuthi bane-asthma.

Lolu hlobo lwe-asthma lubangelwa ukungena kwamaseli egazi eosinophil. Ngenkathi imbangela ngqo ingaziwa, ama-eosinophil angaba neqhaza ekuvukeleni komoya nasekucinaneni okubonakala ezinhlotsheni zendabuko zesifuba somoya.

I-asthma ye-eosinophilic ingafaka izimpawu ezinzima kakhulu kunezinhlobo zesifo somoya. Ungase futhi ube nokuqubuka okuvame kakhulu. Izinketho zokwelashwa zifana ne-asthma enamandla, kepha izindlela zakho eziqondile zokwelashwa zivame ukuba nolaka kakhulu.

Khuluma nodokotela wakho ngalezi zinketho ezilandelayo ezisetshenziswa ekwelapheni lolu hlobo lwesifuba somoya.

I-corticosteroids emuncwe nangomlomo

I-corticosteroids emuncwe imvamisa iyindlela yokuqala yokwelashwa yezinhlobo eziphikelelayo, kufaka phakathi i-eosinophilic, asthma. Basebenza ngokunciphisa ukuvuvukala komoya okunikela ekucinaneni, okwenza ukwazi ukuphefumula kalula.

Ungadinga futhi ezinye izinhlobo ze-corticosteroids ze-asthma eosinophilic ngomlomo uma izimpawu zakho zinzima kakhulu.

Kodwa-ke, ama-steroids omlomo abeka ingozi yemiphumela emibi yesikhathi eside, kufaka phakathi:

• ukukhumuzeka kwamathambo
• ukuzuza kwesisindo
• isifo sikashukela

Izinguquko zeLeukotriene

Le mithi yokwelashwa ivame ukunikezwa abantu abane-asthma kanye ne-allergies. Basebenza ngokunciphisa ama-leukotrienes emzimbeni, afaka isandla ekuvukeleni.

Udokotela wakho angakunikeza okunye kokulandelayo:

• i-montelukast sodium (i-Singulair)
• zafirlukast (I-Accolate)
• zileuton (Zyflo)

I-Biologics

I-Biologics iyindlela evelayo yokwelashwa kwe-asthma okunzima. Le mithi ihanjiswa ngomjovo, imvamisa udokotela wakho. Zinciphisa ukuvuvukala ngokukhomba kuma-molecule wokuvuvukala, amaseli, nama-antibodies.

Ngalesi sizathu, i-biologics ibhekwa njengehlinzeka ngemithi ethe xaxa "eyenziwe ngezifiso" uma iqhathaniswa neminye imithi yesifuba somoya.

Ungaba yilungu le-biologics uma uqhubeka nokuba nama-flare-ups njalo yize uthatha imishanguzo yesilawuli sakho futhi uvikela nezimbangela.

I-biologics nayo inganciphisa i-asthma yasebusuku, iphinde inciphise inani lokuvakashelwa esibhedlela ngenxa yokuhlaselwa yisifuba somoya.

Okwamanje kunezinhlobo ezinhlanu ze-biologics ezitholakalayo zokwelashwa kwe-asthma okunzima:

• i-benralizumab (Fasenra)
• dupilumab (Dupixent)
• mepolizumab (Nucala)
• i-omalizumab (Xolair)
• i-reslizumab (Cinqair)

Kulezi biologics, iFasenra, iNucala, neCinqair konke kubhekise kuma-eosinophil ngqo. Ama-biologics amaningi asentuthukweni yokwelashwa okubhekiswe kakhulu.

Uma udokotela wakho encoma i-biologics ye-asthma yakho ye-eosinophilic, ungalindela ukuthola le mijovo njalo emavikini amabili kuya kwangu-8 esikhathini esingangezinyanga ezine.

Ama-inhalers wokutakula

Yize kungesilo uhlobo lokwelashwa lwesikhathi eside, kusengumqondo omuhle ukuthi ube ne-inhaler yokutakula esandleni uma une-asthma eosinophilic.

Ebizwa nangokuthi i-inhaler yokusiza ngokushesha, le mithi isebenza ngokunciphisa izimpawu zokuqhuma nokuvula izindlela zakho zomoya ukusiza ukuvimbela ukuhlaselwa yisifuba somoya.

Inkinga ngama-inhalers okutakula ukuthi ngeke zivimbele izimpawu zesifuba somoya njengoba kwenza izilawuli zesikhathi eside. Ukuthembela kulezi zinhlobo ze-inhalers kaningi futhi kungazenza zingasebenzi kangako ngoba amaphaphu akho azozijwayela.

Shayela udokotela wakho uma usebenzisa i-inhaler yakho yokutakula ngaphezu kwezikhathi ezimbalwa ngesonto.

Ama-anticholinergics

Ama-anticholinergics yimithi evimba i-neurotransmitter ebizwa nge-acetylcholine. Le mithi ngokwesiko yelapha ukungabambeki kanye nesinye esisebenza ngokweqile, kanye nesifo esingapheliyo se-pulmonary disease (COPD).

Lezi zinhlobo zemithi zingasiza ekwelapheni i-asthma enamandla. Ama-anticholinergics akhulula imisipha yomoya futhi akusize uphefumule kalula.

Ukuthatha le mithi nakho kungenza ukuthi kungabi namathuba amancane okuthi uzodinga i-oral steroids esikhathini eside.

Ukuthatha

I-asthma eosinophilic ingenye yama-subtypes anzima kakhulu ukwelashwa. Kuzodingeka ukuthi uzame izinketho ezahlukahlukene ukuze ubone ukuthi yini okusebenza kahle kakhulu.

I-asthma yakho ibhekwa "njengokulawulwa kahle" uma unezimpawu izinsuku ezimbili ngesonto noma ngaphansi.

Khuluma nodokotela wakho uma uhlangabezana nezimpawu zesifuba somoya njalo futhi uma isimo sakho siphazamisa imisebenzi yansuku zonke. Bangase banikeze umuthi onamandla wesikhathi eside noma i-biologics ukusiza ukuthuthukisa izimpawu zakho nekhwalithi yempilo.

Ukuphatha izimpawu zesifo se-asthma se-eosinophilic kungasiza ekunciphiseni ubungozi bokubamba amaphaphu nezinye izinkinga zesikhathi eside.

Ungathuthukisa nomphumela wakho wokwelashwa ngokunakekela impilo yakho yonke ngangokunokwenzeka, kufaka phakathi:

• ukudla okunempilo
• ukulala ngokwanele
• ukuphathwa kwengcindezi

Ukugwema izimbangela, njengokuxineka, ukungezwani komzimba nezinto ezithile nezicasuli zamakhemikhali, nakho kunganciphisa ubungozi bokuqhuma.