Isimila samasende iLeydig

Isigaxa samangqamuzana iLeydig yisicubu sesende. Ikhula kumaseli weLeydig. Lawa amangqamuzana kumasende akhipha i-hormone yowesilisa, i-testosterone.

Ayaziwa imbangela yalesi simila. Azikho izici eziyingozi ezaziwayo zalesi sifo. Ngokungafani nezicubu zeseli lesigciwane samasende, lesi sifo asibonakali sixhumene namasende angafunwanga.

Izicubu zamaseli eLeydig zakha inani elincane kakhulu lazo zonke izicubu zamasende. Zivame ukutholakala kwabesilisa abaphakathi kweminyaka engama-30 nengama-60 ubudala. Lesi isimila asijwayelekile ezinganeni ngaphambi kokuthomba, kepha singadala ukuthomba ngaphambi kwesikhathi.

Kungase kungabikho zimpawu.

Lapho izimpawu zenzeka, zingabandakanya:

• Ukungakhululeki noma ubuhlungu esendeni
• Ukukhuliswa kwesende noma ukushintsha ngendlela elizizwa ngayo
• Ukukhula okwedlulele kwezicubu zamabele (gynecomastia) - noma kunjalo, lokhu kungenzeka ngokujwayelekile kubafana abasebasha abangenawo umdlavuza wamasende
• Ubunzima ku-scrotum
• Isigaxa noma ukuvuvukala kusende ngalinye
• Ubuhlungu esiswini esingezansi noma emuva
• Ayikwazi ukuzala izingane (ukungazali)

Izimpawu kwezinye izingxenye zomzimba, ezifana namaphaphu, isisu, isinqe, emuva, noma ubuchopho nazo zingavela uma umdlavuza usakazekile.

Ukuhlolwa komzimba kuvamise ukuveza isigaxa esiqinile kwelinye lamasende. Lapho umhlinzeki wezempilo ephethe i-flashlight yaze yafika esikhwameni, isibani asidluli esigaxeni. Lokhu kuhlolwa kubizwa ngokuthi ukuguqulwa komzimba.

Ezinye izivivinyo zifaka:

• Ukuhlolwa kwegazi kwezimpawu zesimila: i-alpha fetoprotein (AFP), i-chorionic gonadotropin (beta HCG), ne-lactate dehydrogenase (LDH)
• I-CT scan esifubeni, esiswini kanye nesinqe ukubheka ukuthi umdlavuza ususakazekile yini
• I-Ultrasound yesikhwama

Ukuhlolwa kwezicubu kuvame ukwenziwa ngemuva kokuba isende lonke selisuswe ngokuhlinzwa (orchiectomy).

Ukwelashwa kwesimila seseli leLeydig kuncike esigabeni saso.

• Umdlavuza weSigaba I awusakazekanga ngale kwesende.
• Umdlavuza weSigaba II usabalalele kuma-lymph node esiswini.
• Umdlavuza weSigaba III usabalale wadlula ngale kwama-lymph node (mhlawumbe kuze kufike esibindini, emaphashini, noma ebuchosheni).

Kuhlinzwa ukuze kususwe isende (orchiectomy). Ama-lymph node aseduze nawo angasuswa (i-lymphadenectomy).

I-Chemotherapy ingasetshenziselwa ukwelapha lesi sifo. Njengoba izicubu zamangqamuzana eLeydig zingandile, lezi zindlela zokwelashwa azifundiswanga njengokulashwa kwamanye amagciwane omdlavuza ajwayelekile.

Ukujoyina iqembu lokusekelwa lapho amalungu abelana ngokuhlangenwe nakho okuvamile nezinkinga kungasiza ekunciphiseni ukucindezeleka kokugula.

Umdlavuza wamasende ungenye yomdlavuza owelaphekayo nolaphekayo. Ukubukeka kubi kakhulu uma isimila singatholakali kusenesikhathi.

Umdlavuza ungadlulela nakwezinye izingxenye zomzimba. Amasayithi ajwayelekile afaka:

• Isisu
• Amaphaphu
• Indawo ye-Retroperitoneal (indawo eseduze kwezinso ngemuva kwezinye izitho esiswini)
• Umqolo

Izinkinga zokuhlinzwa zingafaka:

• Ukopha nokutheleleka
• Ukuzala (uma amasende womabili esusiwe)

Uma uneminyaka yobudala yokuzala, buza umhlinzeki wakho ngezindlela zokonga isidoda sakho ukuze sisetshenziswe kamuva.

Shayela umhlinzeki wakho uma unezimpawu zomdlavuza wamasende.

Ukwenza ukuzihlola kwamasende (TSE) inyanga nenyanga kungasiza ukuthola umdlavuza wamasende kusenesikhathi, ngaphambi kokuba usabalale. Ukuthola umdlavuza wamasende kusenesikhathi kubalulekile ekwelashweni ngempumelelo nasekusindeni.

Isimila - iseli leLeydig; Isimila samasende - Leydig

• I-anatomy yokuzala yowesilisa

I-Friedlander TW, umdlavuza omncane we-E testicular. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, abahleli. I-Abeloff’s Clinical Oncology. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2020: isahluko 83.

Iwebhusayithi yeNational Cancer Institute. Ukwelashwa komdlavuza wamasende (PDQ) - inguqulo yezobuchwepheshe yezempilo. www.cancer.gov/types/testicular/hp/testicular-treatment-pdq. Kubuyekezwe uMeyi 21, 2020. Kufinyelelwe ngoJulayi 21, 2020.

UStephenson AJ, uGilligan TD. Izimpawu zamasende. Ku: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, ama-eds. ICampbell-Walsh-Wein Urology. Umhla ka-12. IPhiladelphia, PA: Elsevier; 2021: isahluko 76.