I-Polymyalgia rheumatica

I-Polymyalgia rheumatica (PMR) yisifo sokuvuvukala. Kubandakanya izinhlungu nokuqina emahlombe futhi kuvame ukuba sezinqeni.

I-Polymyalgia rheumatica ivame ukwenzeka kubantu abaneminyaka engaphezu kwengu-50 ubudala. Imbangela ayaziwa.

I-PMR ingenzeka ngaphambi noma nge-giant cell arteritis (GCA; ebizwa nangokuthi i-temporal arteritis). Lesi yisimo lapho kuvutha khona imithambo yegazi ehambisa igazi ekhanda nasesweni.

I-PMR kwesinye isikhathi kungaba nzima ukukuhlukanisa ngaphandle kwesifo samathambo (RA) kumuntu osekhulile. Lokhu kwenzeka lapho izivivinyo ze-rheumatoid factor kanye ne-anti-CCP antibody zingethile.

Uphawu oluvame kakhulu ubuhlungu nokuqina emahlombe womabili nasentanyeni. Ubuhlungu nokuqina kubi kakhulu ekuseni. Lobuhlungu buvame ukuqhubekela ezinqeni.

Ukukhathala nakho kukhona. Abantu abakulesi simo bakuthola kunzima ukuvuka embhedeni nokuhambahamba.

Ezinye izimpawu zifaka:

• Ukunciphisa ukudla, okuholela ekunciphiseni isisindo
• Ukucindezeleka
• Imfiva

Ukuhlolwa kwelebhu kukodwa akukwazi ukuxilonga i-PMR. Iningi labantu abanalesi simo linamamaki aphezulu okuvuvukala, njengezinga le-sedimentation (ESR) namaprotheni asebenza ngo-C.

Eminye imiphumela yokuhlolwa yalesi simo ifaka phakathi:

• Amazinga angajwayelekile wamaprotheni egazini
• Izinga elingajwayelekile lamaseli amhlophe egazi
• I-anemia (ukubalwa kwegazi okuphansi)

Lezi zivivinyo zingasetshenziswa futhi ukuqapha isimo sakho.

Kodwa-ke, ukuhlolwa kwe-imaging njenge-x-ray ehlombe noma okhalweni akuvame ukusiza. Lezi zivivinyo zingaveza ukulimala okuhlangene okungahlobene nezimpawu zakamuva. Ezimweni ezinzima, i-ultrasound noma i-MRI yehlombe ingenziwa. Lokhu kuhlolwa kwe-imaging kuvame ukukhombisa i-bursitis noma amazinga aphansi wokuvuvukala okuhlangene.

Ngaphandle kokwelashwa, i-PMR ayibangcono. Kodwa-ke, amanani aphansi we-corticosteroids (njenge-prednisone, 10 kuya ku-20 mg ngosuku) anganciphisa izimpawu, imvamisa kungakapheli usuku noma ezimbili.

• Umthamo kufanele wehliswe kancane kancane ube sezingeni eliphansi kakhulu.
• Ukwelashwa kudinga ukuqhubeka unyaka owodwa kuya kwemibili. Kwabanye abantu, kudingeka ukwelashwa okude kakhulu ngamanani aphansi e-prednisone.

I-Corticosteroids ingadala imiphumela emibi eminingi njengokuzuza kwesisindo, ukukhula kwesifo sikashukela noma i-osteoporosis. Udinga ukubhekelwa eduze uma uphuza le mithi. Uma usengozini ye-osteoporosis, umhlinzeki wakho wezokunakekelwa kwempilo angakutusa ukuthi uthathe imithi yokuvikela lesi simo.

Kubantu abaningi, i-PMR iyahamba nokwelashwa ngemuva kweminyaka engu-1 kuye kwengu-2. Ungase uyeke ukuthatha imishanguzo ngemuva kwaleli phuzu, kodwa hlola umhlinzeki wakho kuqala.

Kwabanye abantu, izimpawu ziyabuya ngemuva kokuyeka ukuthatha i-corticosteroids. Kulezi zimo, omunye umuthi onjenge-methotrexate noma i-tocilizumab ungadingeka.

IGiant cell arteritis nayo ingaba khona noma ingakhula ngokuhamba kwesikhathi. Uma kunjalo, umthambo wesikhashana uzodinga ukuhlolwa.

Izimpawu ezinzima kakhulu zingenza kube nzima kuwe ukuthi usebenze noma uzinakekele ekhaya.

Shayela umhlinzeki wakho uma unobuthakathaka noma ukuqina ehlombe nasentanyeni okungapheli. Futhi xhumana nomhlinzeki wakho uma unezimpawu ezintsha ezifana nomkhuhlane, ikhanda elibuhlungu, nobuhlungu ngokuhlafuna noma ukulahleka kombono. Lezi zimpawu zingavela ku-giant cell arteritis.

Akukho ukuvimbela okwaziwayo.

PMR

UDejaco C, uSingh YP, uPerel P, et al. Izincomo zika-2015 zokuphathwa kwe-polymyalgia rheumatica: i-European League Against Rheumatism / American College of Rheumatology isinyathelo sokubambisana. I-Arthritis Rheumatol. 2015; 67 (10): 2569-2580. I-PMID: 2635874 www.ncbi.nlm.nih.gov/pubmed/26352874.

UHellmann DB. I-Giant cell arteritis, i-polymyalgia rheumatica, ne-Takayasu's arteritis. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, abahleli. Incwadi kaKelley noFirestein yeRheumatology. Umhlaka 10. IPhiladelphia, PA: Elsevier; 2017: isahluko 88.

IKermani TA, iWarrington KJ. Intuthuko nezinselelo ekuhlolweni nasekwelapheni i-polymyalgia rheumatica. I-Ther Adv Musculoskelet Dis. 2014; 6 (1): 8-19. I-PMID: 24489611 www.ncbi.nlm.nih.gov/pubmed/24489611.

USalvarani C, uCiccia F, uPipitone N. Polymyalgia rheumatica kanye ne-giant cell arteritis. Ku: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, abahleli. I-Rheumatology. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2019: isahluko 166.