Yini i-calcitonin futhi yenzani

-Delile

• Yenzelwe ini
• Lapho ungasebenzisi
• Isetshenziswa kanjani
• Imiphumela emibi engaba khona
• Lapho ukuhlolwa kwe-calcitonin kwenziwa

I-Calcitonin yi-hormone ekhiqizwa ku-thyroid enomsebenzi wokwehlisa ukugxila kwe-calcium egazini, kunciphisa ukumuncwa kwe-calcium ngamathumbu nokuvimbela ukusebenza kwama-osteoclasts.

Ngakho-ke, i-calcitonin ibaluleke kakhulu ekugcineni impilo yethambo, yingakho kunezidakamizwa ezinale hormone ekwakheni, ezisetshenziswa ezifweni ezinjenge-osteoporosis, isifo sikaPaget noma iSudeck's syndrome, ngokwesibonelo.

Yenzelwe ini

Izidakamizwa zeCalcitonin zisetshenziselwa ukwelapha izifo ezinjenge:

• I-osteoporosis, noma ubuhlungu bethambo obuhambisana nayo, lapho amathambo mancane kakhulu futhi ebuthakathaka;
• Isifo sikaPaget sethambo, okuyisifo esihamba kancane futhi esiqhubekela phambili esingadala ushintsho kusayizi nokuma kwamathambo athile;
• I-Hypercalcemia, ebonakala ngenani eliphakeme kakhulu le-calcium egazini;
• I-Reflex symptomatic dystrophy, okuyisifo esidala ukuguquka kobuhlungu namathambo, okungafaka ukulahleka kwethambo lendawo.

ICalcitonin inomsebenzi wokulawula amazinga e-calcium egazini ngakho-ke isetshenziselwa ukubuyisa ukulahleka kwethambo. Ngaphezu kwalokho, kukholelwa nokuthi le hormone ibandakanyeka ekwakhekeni kwamathambo.

Lapho ungasebenzisi

Ngokuvamile, i-calcitonin esetshenziswa emithini enale hormone yi-salmon calcitonin, yingakho iphikiswa kubantu abanezinto ezingezwani nokwaliwa yile nto, noma kunoma iyiphi enye ingxenye yefomula.

Ngaphezu kwalokho, futhi akunconyelwe abesifazane abakhulelwe, abancelisayo kanye nabantu abangaphansi kweminyaka engu-18.

Isetshenziswa kanjani

Umthamo onconyiwe we-calcitonin uncike enkingeni ezolashwa:

• I-osteoporosis: Umthamo onconywayo yi-50 IU ngosuku noma i-100 IU ngosuku noma ngalo lonke olunye usuku, ngomjovo ongaphansi kwesikhumba noma we-intramuscular.
• Ubuhlungu bamathambo: Umthamo onconywayo yi-100 kuya ku-200 IU, ngosuku ngokufakwa kancane emithanjeni yesisombululo se-saline yomzimba noma ngomjovo ongena ngaphansi noma wesikhumba, ngamanani ahlukanisiwe, asatshalaliswa usuku lonke, kuze kube kutholakala impendulo egculisayo.
• Isifo sikaPaget: Umthamo onconywayo yi-100 IU ngosuku noma ngalo lonke olunye usuku, ngomjovo ongena ngaphansi noma we-intramuscular.
• Ukwelashwa okuphuthumayo kwenkinga ye-hypercalcemic: Umthamo onconywayo yi-5 kuya ku-10 IU ngekhilogremu yesisindo somzimba ngosuku, ngokufakwa ngaphakathi, okungenani amahora ayisithupha, noma ngomjovo omncane wokufaka emithanjeni emi-2 kuye kwengu-4 ehlukaniswe ngosuku.
• Ukwelashwa isikhathi eside kwe-hypercalcemia engapheli: Umthamo onconywayo yi-5 kuya ku-10 IU ngekhilogremu yesisindo somzimba ngosuku, ngomjovo ongaphansi kwesikhumba noma we-intramuscular, ngomthamo owodwa noma ngemithamo emibili ehlukanisiwe.
• I-Reflex dysstrophy enezimpawu: Umthamo onconywayo yi-100 IU ngosuku ngomjovo ongaphansi noma we-intramuscular wamaviki ama-2 kuye kwayi-4.

Kukudokotela ukuthi unqume ukuthi umuthi kufanele uqhubeke isikhathi esingakanani.

Imiphumela emibi engaba khona

Imiphumela emibi kakhulu engenzeka ngokusetshenziswa kwe-calcitonin yisiyezi, ikhanda, ukuguquka kokunambitheka, ubomvu ebusweni noma entanyeni, isicanucanu, isifo sohudo, ubuhlungu besisu, ubuhlungu bamathambo noma obuhlangene nokukhathala.

Ngaphezu kwalokho, yize kungajwayelekile, ukuphazamiseka kokubona, umfutho wegazi ophakeme, ukuhlanza, ubuhlungu emisipheni, emathanjeni noma emalungeni, izimpawu zomkhuhlane nokuvuvukala kwezingalo noma imilenze nakho kungenzeka.

Lapho ukuhlolwa kwe-calcitonin kwenziwa

Ukuhlolwa kokulinganiswa kwamanani we-calcitonin kukhonjiswa ikakhulukazi ukukhomba nokuqapha ubukhona be-medullary thyroid carcinoma, isifo esibangela ukuphakama okukhulu kwale hormone.

Ngaphezu kwalokho, i-calcitonin ingasiza futhi ukukhomba ezinye izimo, njenge-hyperplasia yamaseli e-thyroid C, okungamaseli akhiqiza i-calcitonin, kanye nokuhambisana nezinye izinhlobo zomdlavuza, njenge-leukemia, umdlavuza wamaphaphu, isifuba, amanyikwe noma i-prostate, isibonelo. Thola okuningi mayelana nokuthi kwenziwa yini ukuhlolwa kwe-calcitonin nokuthi kwenziwa kanjani.