Kutholwe isici sokusebenza kweplatelet

Ukukhubazeka kokusebenza kweplatelet kuyizimo ezivimbela ama-clotting element egazini okuthiwa ama-platelet ukuthi asebenze ngendlela efanele ngayo. Igama elitholakele lisho ukuthi lezi zimo azikho lapho kuzalwa.

Ukuphazamiseka kweplatelet kungathinta inani lama-platelet, ukuthi asebenza kahle kangakanani, noma zombili. Ukuphazamiseka kweplatelet kuthinta ukujiya kwegazi okujwayelekile.

Ukuphazamiseka okungadala izinkinga ekusebenzeni kweplatelet kufaka:

• Idiopathic thrombocytopenic purpura (ukuphazamiseka kwegazi lapho amasosha omzimba abulala khona amaplatelet)
• I-leukemia engapheli (umdlavuza wegazi oqala ngaphakathi komnkantsha wethambo)
• I-myeloma eminingi (umdlavuza wegazi oqala kumaseli e-plasma emnkantsheni wethambo)
• I-myelofibrosis eyinhloko (ukuphazamiseka komnkantsha lapho umnkantsha ubuyiselwa khona yizicubu ezibomvu)
• I-Polycythemia vera (isifo semnkantsha esiholela ekwandeni okungavamile kwenani lamaseli egazi)
• I-thrombocythemia eyinhloko (ukuphazamiseka komnkantsha lapho umnkantsha ukhiqiza khona amaplatelets amaningi)
• I-thrombotic thrombocytopenic purpura (ukuphazamiseka kwegazi okwenza amahlule egazi akhe emithanjeni yegazi emincane)

Ezinye izimbangela zifaka:

• Izinso (ukwehluleka kwezinso)
• Imithi efana ne-aspirin, ibuprofen, ezinye izidakamizwa ezilwa nokuvuvukala, i-penicillin, i-phenothiazines, ne-prednisone (ngemuva kokusebenzisa isikhathi eside)

Izimpawu zingafaka noma yikuphi okulandelayo:

• Izinkathi ezinzima zokuya esikhathini noma ukuphuma kwegazi isikhathi eside (izinsuku ezingaphezu kwezingu-5 isikhathi ngasinye)
• Ukopha okungavamile kwesitho sangasese sowesifazane
• Igazi emchameni
• Ukopha ngaphansi kwesikhumba noma emisipheni
• Ukulimaza kalula noma ukukhomba izindawo ezibomvu esikhunjeni
• Ukopha emathunjini okuholela ekunyakazeni kwamathumbu anegazi, amnyama amnyama, noma okulindile; noma uhlanza igazi noma okokusebenza okubukeka njengezizathu zekhofi
• Ukopha ngamakhala

Ukuhlolwa okungenziwa kufaka:

• Umsebenzi wePlatelet
• Ukubalwa kweplatelet
• I-PT ne-PTT

Ukwelashwa kuhloswe ukulungisa imbangela yenkinga:

• Ukuphazamiseka kwemnkantsha we-Bone kuvame ukwelashwa ngokumpontshelwa kweplatelet noma ukususa ama-platelet egazini (platelet pheresis).
• I-Chemotherapy ingasetshenziselwa ukwelapha isimo esingaphansi esidala inkinga.
• Ukukhubazeka kokusebenza kweplatelet okubangelwa ukwehluleka kwezinso kulashwa nge-dialysis noma ngemithi.
• Izinkinga zeplatelet ezibangelwa umuthi othile zilashwa ngokumiswa komuthi.

Isikhathi esiningi, ukuphatha imbangela yenkinga kulungisa iphutha.

Izinkinga zingafaka:

• Ukopha okungayeki kalula
• I-anemia (ngenxa yokopha ngokweqile)

Shayela umhlinzeki wakho wezempilo uma:

• Wopha futhi awazi imbangela
• Izimpawu zakho ziba zimbi kakhulu
• Izimpawu zakho azithuthuki ngemuva kokuba welashelwe isici sokusebenza kweplatelet esitholakele

Ukusebenzisa imithi njengoba kuqondisiwe kunganciphisa ubungozi bokukhubazeka okuhlobene nezidakamizwa okutholwe yizidakamizwa. Ukwelapha ezinye izifo kunganciphisa ubungozi. Amanye amacala awakwazi ukuvinjelwa.

Kutholakale ukuphazamiseka kweplatelet yekhwalithi; Ukuphazamiseka okutholakele komsebenzi weplatelet

• Ukwakheka kwegazi
• Amahlule egazi

UDiz-Kucukkaya R, uLopez JA. Ukuphazamiseka okutholakele komsebenzi weplatelet. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 130.

IHholo JE. I-hemostasis negazi coagulation. Ku: IHholo JE, kuhleliwe. Incwadi kaGuyton neHholo yePhysical Physiology. Umhlaka 13. IPhiladelphia, PA: Elsevier; 2016: isahluko 37.

UJobe SM, uDi Paola J. Congenital futhi bathola ukuphazamiseka kokusebenza kweplatelet nenombolo. Ku: Amakhishi CS, Kessler CM, Konkle BA, Streiff MB, Garcia DA, eds. I-Hemostasis yokubonisana ne-Thrombosis. Umhla wesi-4. IPhiladelphia, PA: Elsevier; 2019: isahluko 9.