I-Thrombocytopenia

I-Thrombocytopenia yinoma yikuphi ukuphazamiseka lapho kunenani eliphansi ngokungavamile lamaplatelets. Ama-platelet ayizingxenye zegazi ezisiza igazi ukuba limile. Lesi simo kwesinye isikhathi sihambisana nokopha okungavamile.

I-Thrombocytopenia ivame ukuhlukaniswa ngezimbangela ezintathu ezinkulu zamaplatelet aphansi:

1. Awekho amaplatelet anele enziwe emnkantsheni wethambo
2. Ukwanda kokwephuka kwamagazi egazini
3. Ukwanda kokuwohloka kwama-platelet ebuchosheni noma esibindini

Umnkantsha wakho awukwazi ukwenza amaplatelet anele uma unalezi zimo ezilandelayo:

• I-aplastic anemia (ukuphazamiseka lapho umnkantsha ungenzi amaseli wegazi anele)
• Umdlavuza emnkantsheni wethambo, njenge-leukemia
• I-Cirrhosis (isibazi sesibindi)
• Ukushoda kwefolate
• Izifo emnkantsheni wethambo (ezingavamile kakhulu)
• I-Myelodysplastic syndrome (umnkantsha awenzi amaseli wegazi anele noma wenze amaseli angasebenzi kahle)
• Ukuntuleka kwe-Vitamin B12

Ukusetshenziswa kwemithi ethile kungaholela ekukhiqizweni okuphansi kwama-platelet emnkantsheni wethambo. Isibonelo esivame kakhulu ukwelashwa ngamakhemikhali.

Izimo zezempilo ezilandelayo zibangela ukwanda kwamaplatelets:

• Ukuphazamiseka lapho amaprotheni alawula ukujiya kwegazi asebenza kakhulu, imvamisa ngesikhathi sokugula okungathi sína (i-DIC)
• Ukubalwa kweplatelet okuphansi okubangelwa izidakamizwa
• Ubende obukhulisiwe
• Ukuphazamiseka lapho amasosha omzimba abhubhisa khona amaplatelets (ITP)
• Ukuphazamiseka okubanga ukuthi amahlule egazi akhe emithanjeni yegazi emincane, kubangele inani eliphansi leplatelet (TTP)

Ungahle ungabi nazimpawu. Noma ungaba nezimpawu ezijwayelekile, njenge:

• Ukopha emlonyeni nasezinsinini
• Ukulimaza
• Ukopha ngamakhala
• I-Rash (ikhomba izindawo ezibomvu ezibizwa nge-petechiae)

Ezinye izimpawu zincike embangela.

Umhlinzeki wakho wokunakekelwa kwezempilo uzokwenza isivivinyo somzimba abuze ngomlando nezimpawu zakho zezokwelapha. Ukuhlolwa okulandelayo kungenziwa:

• Qedela ukubalwa kwegazi (CBC)
• Ukuhlolwa kwegazi (PTT ne-PT)

Olunye uvivinyo olungasiza ukuxilonga lesi simo lubandakanya ukufiseleka komnkantsha noma i-biopsy.

Ukwelashwa kuncike embangela yalesi simo. Kwezinye izimo, ukumpontshelwa ama-platelet kungadingeka ukumisa noma ukuvimbela ukuphuma kwegazi.

Umphumela uncike ekuphazamisweni okubangela ukubalwa kweplatelet okuphansi.

Ukopha kakhulu (ukopha) yinkinga enkulu. Ukopha kungahle kwenzeke ebuchosheni noma emgodini wamathumbu.

Shayela umhlinzeki wakho uma uthola ukopha noma ukulimaza okungaqondakali.

Ukuvimbela kuncike embangela ethile.

Ukubalwa kweplatelet okuphansi - i-thrombocytopenia

Abrams CS. I-Thrombocytopenia. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 163.

U-Arnold DM, iLungu lePhalamende likaZeller, uSmith JW, uNazy I. Izifo zenombolo yeplatelet: immune thrombocytopenia, neonatal alloimmune thrombocytopenia, ne-posttransfusion purpura. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 131.

I-Warkentin TE. I-Thrombocytopenia ebangelwa ukubhujiswa kweplatelet, hypersplenism, noma i-hemodilution. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 132.