I-CMV - i-gastroenteritis / colitis
I-CMV gastroenteritis / colitis ukuvuvukala kwesisu noma kwamathumbu ngenxa yokutheleleka nge-cytomegalovirus.
Leli gciwane elifanayo lingadala futhi:
- Ukutheleleka kwamaphaphu
- Ukutheleleka ngemuva kweso
- Ukutheleleka kwengane ngenkathi isesibelethweni
I-Cytomegalovirus (CMV) igciwane lohlobo lwe-herpes. Lihlobene negciwane elibanga ingxibongo.
Ukutheleleka nge-CMV kuvame kakhulu. Isatshalaliswa ngamathe, umchamo, amaconsi okuphefumula, ukuxhumana ngokocansi nokumpontshelwa igazi. Iningi labantu liyavezwa ngesikhathi esithile, kepha esikhathini esiningi, igciwane likhiqiza izimpawu ezimnene noma ezingekho nhlobo kubantu abaphilile.
Ukutheleleka okukhulu kwe-CMV kungenzeka kubantu abanamasosha omzimba abuthakathaka ngenxa ye:
- Ingculaza
- Ukwelashwa ngamakhemikhali ngomdlavuza
- Ngesikhathi noma ngemuva komnkantsha wethambo noma ukufakelwa komzimba
- I-ulcerative colitis noma isifo seCrohn
Imvamisa, ukutheleleka okungathi sína kwe-CMV okubandakanya ipheshana le-GI kwenzeke kubantu abanamasosha omzimba anempilo.
Isifo se-CMV emathunjini singathinta indawo eyodwa noma umzimba wonke. Izilonda zingenzeka ku-esophagus, esiswini, emathunjini amancane, noma kukholoni. Lezi zilonda zihlotshaniswa nezimpawu ezinjengalezi:
- Ubuhlungu besisu
- Kunzima ukugwinya noma ubuhlungu ngokugwinya
- Isicanucanu
- Ukuhlanza
Lapho amathumbu ebandakanyeka, izilonda zingadala:
- Ubuhlungu besisu
- Izitulo ezinegazi
- Uhudo
- Imfiva
- Ukwehla kwesisindo
Ukutheleleka okunzima kakhulu kungaholela ekopheni emathunjini noma emgodini odongeni lwamathumbu (i-perforation).
Ukuhlolwa okungenziwa kufaka phakathi:
- I-Barium enema
- I-Colonoscopy ene-biopsy
- I-endoscopy ephezulu (i-EGD) ene-biopsy
- Isiko lesiko lokunqanda ezinye izimbangela zokutheleleka
- I-Upper GI nochungechunge lwamathumbu amancane
Ukuhlolwa kwelabhorethri kuzokwenziwa esampuleni yezicubu ezithathwe esiswini noma emathunjini akho. Ukuhlolwa, okufana nesiko lesicubu esiswini noma samathumbu noma i-biopsy, kunquma ukuthi ngabe igciwane likusicubu yini.
Ukuhlolwa kwe-CMV serology kwenziwa ukubheka amasosha omzimba egciwane le-CMV egazini lakho.
Okunye ukuhlolwa kwegazi okubheka ubukhona kanye nenombolo yezinhlayiya zegciwane egazini nakho kungenziwa.
Ukwelashwa kuhloselwe ukulawula ukutheleleka nokukhulula izimpawu.
Imithi yokulwa negciwane (imithi elwa namagciwane) iyabekwa. Imithi inganikezwa ngomthambo (IV), futhi kwesinye isikhathi ngomlomo, amasonto ambalwa. Imithi esetshenziswa kakhulu yi-ganciclovir ne-valganciclovir, ne-foscarnet.
Kwezinye izimo, ukwelashwa kwesikhathi eside kungadingeka. Umuthi obizwa nge-CMV hyperimmune globulin ungasetshenziswa lapho ezinye izidakamizwa zingasebenzi.
Eminye imithi ingafaka:
- Izidakamizwa ukuvimbela noma ukunciphisa isifo sohudo
- Ama-painkillers (ama-analgesics)
Izithako zokudla okunomsoco noma okunomsoco okunikezwa ngomthambo (IV) kungasetshenziswa ukwelapha ukulahleka kwemisipha ngenxa yalesi sifo.
Kubantu abanamasosha omzimba aphilile, izimpawu ziyaphela ngaphandle kokwelashwa ezimweni eziningi.
Izimpawu ziba nzima kakhulu kulabo abanamasosha omzimba abuthakathaka. Umphumela uncike ekutheni ukuntuleka kwamasosha omzimba kukhulu kangakanani nokutheleleka nge-CMV.
Abantu abane-AIDS bangaba nomphumela omubi kakhulu kunalabo abanamasosha omzimba abuthakathaka ngenxa yesinye isizathu.
Ukutheleleka nge-CMV kuthinta umzimba wonke, noma ngabe kukhona izimpawu zamathumbu kuphela. Ukuthi umuntu wenza kahle kangakanani kuya ngokuthi isebenza kanjani imishanguzo yegciwane lengculaza.
Izidakamizwa ezisetshenziselwa ukulwa naleli gciwane zingadala imiphumela emibi. Uhlobo lomphumela oseceleni luxhomeke kusidakamizwa esithile esisetshenzisiwe. Isibonelo, i-ganciclovir yezidakamizwa inganciphisa inani lakho lamaseli amhlophe egazi. Esinye isidakamizwa, i-foscarnet, singaholela ezinkingeni zezinso.
Shayela umhlinzeki wakho wezokunakekelwa kwezempilo uma unezimpawu ze-CMV gastroenteritis / colitis.
Kukhona ubungozi obukhulu bokutheleleka nge-CMV kubantu abathola ukufakelwa izitho kumuntu onikela nge-CMV. Ukuthatha izidakamizwa ezilwa namagciwane i-ganciclovir (i-cytovene) ne-valganciclovir (i-Valcyte) ngomlomo ngaphambi kokufakelwa kunganciphisa amathuba akho okuthola ukutheleleka okusha noma ukuvuselela ukutheleleka okudala.
Abantu abane-AIDS abaphathwa ngempumelelo ngemishanguzo esebenza kakhulu ye-antiretroviral mancane amathuba okuthi bathole ukutheleleka nge-CMV.
I-colitis - i-cytomegalovirus; I-gastroenteritis - i-cytomegalovirus; Isifo se-CMV emathunjini
- I-anatomy yesisu
- Ulwelwesi lwesisu nesisu
- I-CMV (cytomegalovirus)
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UWilcox CM. Imiphumela yamathumbu yokutheleleka ngegciwane lomzimba lokuzivikela komzimba. Ku: Feldman M, Friedman LS, Brandt LJ, ama-eds. Sleisenger kanye neFordtran's Gastrointestinal and Liver Disease. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2021: isahluko 35.