Ungaba nayo i-testosterone ephansi?

I-testosterone yi-hormone eyenziwe ngamasende. Kubalulekile ekuqhubekeni kobulili bendoda nokubukeka komzimba.

Izimo ezithile zempilo, imithi, noma ukulimala kungaholela ku-testosterone ephansi (low-T). Izinga le-testosterone nalo lehla ngokwemvelo ngokukhula. I-testosterone ephansi ingathinta idrayivu yocansi, imizwa, nezinguquko ezicutshini nasemafutheni.

Ukwelashwa nge-testosterone therapy kungasiza ekunciphiseni izimpawu.

I-testosterone yenza umuntu abukeke futhi azizwe eyindoda. Kumuntu wesilisa, le hormone isiza:

• Gcina amathambo nemisipha kuqinile
• Thola ukukhula kwezinwele nokuthi amanoni asemzimbeni kuphi
• Yenza isidoda
• Gcina i-sex drive kanye ne-erections
• Yenza amangqamuzana abomvu egazi
• Thuthukisa amandla nemizwelo

Kusukela eminyakeni yobudala engama-30 kuye kwengama-40, amazinga e-testosterone angaqala ukwehla kancane. Lokhu kwenzeka ngokwemvelo.

Ezinye izimbangela ze-testosterone ephansi zifaka:

• Imiphumela emibi yezokwelapha, efana ne-chemotherapy
• Ukulimala kwesende noma umdlavuza
• Izinkinga ngezindlala ebuchosheni (i-hypothalamus ne-pituitary) ezilawula ukukhiqizwa kwamahomoni
• Umsebenzi we-thyroid ophansi
• Amafutha omzimba amaningi kakhulu (ukukhuluphala)
• Ezinye izifo, izifo ezingalapheki, ukwelashwa, noma ukutheleleka

Amanye amadoda ane-testosterone ephansi awanazo izimpawu. Abanye bangaba:

• Ukushayela ocansini okuphansi
• Izinkinga zokulungiswa
• Ukubalwa kwesidoda okuphansi
• Izinkinga zokulala ezifana nokuqwasha
• Nciphisa usayizi wamandla nemisipha
• Ukulahleka kwamathambo
• Khulisa emafutheni omzimba
• Ukucindezeleka
• Inkinga yokugxila

Ezinye izimpawu zingaba yingxenye ejwayelekile yokuguga. Isibonelo, kuyinto ejwayelekile ukuzizwa ungabi nasithakazelo kwezocansi njengoba ukhula. Kepha, akuyona into ejwayelekile ukungabi nentshisekelo kwezocansi.

Izimpawu nazo zingabangelwa ezinye izimo, ezifana nomfutho wegazi ophakeme noma isifo sikashukela. Uma ezinye zalezi zimpawu zikuhlupha, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Umhlinzeki wakho kungenzeka ukuthi ahlolwe igazi ukuhlola izinga lakho le-testosterone. Uzobhekwa nezinye izimbangela zezimpawu zakho. Lokhu kufaka phakathi imiphumela emibi yezokwelapha, izinkinga ze-thyroid, noma ukucindezeleka.

Uma une-testosterone ephansi, ukwelashwa kwe-hormone kungasiza. Umuthi osetshenzisiwe yi-testosterone eyenziwe ngumuntu. Le ndlela yokwelashwa ibizwa ngokuthi yi-testosterone replacement therapy, noma i-TRT. I-TRT inganikezwa njengephilisi, ijeli, isichibi, umjovo, noma ukufakelwa.

I-TRT inganciphisa noma ithuthukise izimpawu kwamanye amadoda. Kungasiza ukugcina amathambo nemisipha kuqinile. I-TRT ibonakala iphumelela kakhulu ezinsizweni ezinamazinga aphansi kakhulu e-testosterone. I-TRT ingaba wusizo nakwabesilisa abadala.

I-TRT inobungozi. Lokhu kungafaka:

• Ukungabi nenzalo
• I-prostate ekhulisiwe eholela ebunzimeni bokuchama
• Amahlule egazi
• Ukuwohloka kwenhliziyo
• Izinkinga zokulala
• Izinkinga ze-cholesterol

Ngalesi sikhathi, akucaci ukuthi ngabe i-TRT iyayandisa yini ingozi yokuhlaselwa yisifo senhliziyo, isifo sohlangothi noma umdlavuza wendlala yabesilisa.

Khuluma nomhlinzeki wakho mayelana nokuthi ngabe i-TRT ikulungele yini. Uma ungaboni ushintsho ezimpawu ngemuva kokwelashwa izinyanga ezi-3, mancane amathuba okuthi ukwelashwa kwe-TRT kuzokusiza.

Uma uthatha isinqumo sokuqala i-TRT, qiniseka ukuthi ubona umhlinzeki wakho ukuze ahlolwe njalo.

Shayela umhlinzeki wakho uma:

• Unezimpawu ze-testosterone ephansi
• Unemibuzo noma ukukhathazeka mayelana nokwelashwa

Ukunqamuka kowesilisa; Isizathu; Ukuntuleka kwe-testosterone; Okuphansi-T; Ukushoda kwe-Androgen kowesilisa osekhulile; I-hypogonadism yangaphambi kwesikhathi

U-Allan CA, McLachlin RI. Izinkinga zokushoda kwe-Androgen. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 139.

UMorgentaler A, uZitzmann M, Traish AM, et al. Imiqondo eyisisekelo maqondana nokushoda nokwelashwa kwe-testosterone: izinqumo zomhlaba wonke zokuvumelana kwabachwepheshe. IMayo Clin Proc. 2016; 91 (7): 881-896. I-PMID: 27313122 www.ncbi.nlm.nih.gov/pubmed/27313122.

Iwebhusayithi ye-U.S.Ukudla Nezidakamizwa. Ukuxhumana nokuphepha kwezidakamizwa kwe-FDA: I-FDA iyaxwayisa ngokusebenzisa imikhiqizo ye-testosterone ye-testosterone ephansi ngenxa yokuguga; kudinga ushintsho lwamalebula ukwazisa ngengozi ekhulayo yokuhlaselwa yisifo senhliziyo nokushaywa unhlangothi ngokusetshenziswa. www.fda.gov/drugs/drugsafety/ucm436259.htm. Kubuyekezwe ngoFebhuwari 26, 2018. Kufinyelelwe ngoMeyi 20, 2019.

• AmaHormone
• Impilo Yamadoda