Uhlelo lokulinganisa lwe-Gleason

Umdlavuza wendlala yesinye utholakala ngemuva kokuhlolwa komzimba. Isampuli eyodwa noma eziningi zezicubu zithathwa endlaleni yesinye futhi zihlolwe ngaphansi kwesibonakhulu.

Uhlelo lokugreda lwe-Gleason lubhekisa ekutheni amangqamuzana omdlavuza wakho wendlala abukeka kanjani futhi nokuthi umdlavuza ungathuthuka futhi usabalale kangakanani. Ibanga eliphansi le-Gleason lisho ukuthi umdlavuza ukhula kancane futhi awunolaka.

Isinyathelo sokuqala sokunquma ibanga le-Gleason ukuthola isilinganiso se-Gleason.

1. Lapho ebheka amaseli ngaphansi kwesibonakhulu, udokotela unikeza inombolo (noma ibanga) kumaseli womdlavuza wendlala yesinye phakathi kuka-1 no-5.
2. Leli banga lincike ekutheni amaseli avele ngokungajwayelekile kanjani. IBanga 1 lisho ukuthi amangqamuzana abukeka njengamaseli ejwayelekile wendlala yesinye. Ibanga lesi-5 lisho ukuthi amangqamuzana abukeka ehluke kakhulu kumaseli ejwayelekile e-prostate.
3. Iningi lomdlavuza wendlala yesinye uqukethe amaseli amabanga ahlukile. Ngakho-ke kusetshenziswa amamaki amabili ajwayelekile kakhulu.
4. Isikolo seGleason sinqunywa ngokungeza amamaki amabili ajwayelekile kakhulu. Isibonelo, ibanga elivame kakhulu lamaseli esampula yezicubu kungaba ngamaseli ebanga lesi-3, alandelwe amaseli ebanga lesi-4. Isikolo seGleason salesi sampula sizoba ngu-7.

Izinombolo eziphakeme zikhombisa umdlavuza okhula ngokushesha osethubeni lokusabalala.

Njengamanje amaphuzu aphansi kakhulu anikezwe isimila ibanga lesi-3. Amabanga angaphansi kuka-3 akhombisa okujwayelekile kuya kumaseli ajwayelekile. Iningi lomdlavuza linamaphuzu we-Gleason (isamba samamaki amabili avame kakhulu) phakathi kuka-6 (izikolo ze-Gleason ezi-3 + 3) no-7 (izikolo zeGleason ezi-3 + 4 noma ezi-4 + 3).

Kwesinye isikhathi, kungaba nzima ukuqagela ukuthi abantu bazokwenza kahle kangakanani ngokuya ngezikolo zabo ze-Gleason kuphela.

• Isibonelo, i-tumor yakho ingabelwa amaphuzu we-Gleason angu-7 uma amamaki amabili avame kakhulu abe ngu-3 no-4. I-7 ingavela ngokungeza u-3 + 4 noma ngokungeza u-4 + 3.
• Kukonke, umuntu onamaphuzu we-Gleason angu-7 aqhamuka ngokungeza u-3 + 4 uzwakala enomdlavuza ongahlukumezi kakhulu kunomuntu onamaphuzu we-Gleason angu-7 avela ngokungeza u-4 + 3. Lokho kungenxa yokuthi umuntu one-4 + 3 = Ibanga lesi-7 linamaseli amaningi ebanga lesi-4 kunamaseli ebanga lesi-3. Amaseli weBanga lesi-4 ajwayelekile kakhulu futhi maningi amathuba okusabalala kunamaseli ebanga lesi-3.

Uhlelo olusha lwe-5 Grade Group lusanda kwenziwa. Lolu hlelo luyindlela engcono yokuchaza ukuthi umdlavuza uzoziphatha kanjani futhi uphendule ekwelashweni.

• Iqembu leBanga 1: Isilinganiso se-Gleason 6 noma ngaphansi (umdlavuza osezingeni eliphansi)
• Iqembu leBanga 2: Isilinganiso se-Gleason 3 + 4 = 7 (umdlavuza osezingeni eliphakathi)
• Ibanga leqembu lesi-3: Isilinganiso se-Gleason 4 + 3 = 7 (umdlavuza osezingeni eliphakathi)
• Ibanga leqembu lesi-4: Isilinganiso se-Gleason 8 (umdlavuza osezingeni eliphakeme)
• Iqembu leBanga lesi-5: Isilinganiso se-Gleason 9 kuya ku-10 (umdlavuza osezingeni eliphakeme)

Iqembu eliphansi likhombisa ithuba elingcono lokwelashwa okuphumelelayo kuneqembu eliphakeme. Iqembu eliphakeme lisho ukuthi amangqamuzana amaningi omdlavuza abukeka ehlukile kumaseli ajwayelekile. Iqembu eliphakeme libuye lisho ukuthi kungenzeka ukuthi isimila sisakazeke ngolaka.

Ukubekwa kusiza wena nodokotela wakho ukunquma izinketho zokwelashwa, kanye ne:

• Isigaba somdlavuza, esikhombisa ukuthi umdlavuza ususabalale kangakanani
• Umphumela wokuhlolwa kwe-PSA
• Impilo yakho iyonke
• Isifiso sakho sokuhlinzwa, imisebe yelanga, noma imishanguzo yamahomoni, noma ungalashwa nhlobo

Umdlavuza wendlala yesinye - Gleason; I-Adenocarcinoma prostate - iGleason; Ibanga le-Gleason; Isikolo seGleason; Iqembu leGleason; Umdlavuza wendlala yesinye - iqembu lebanga lesi-5

I-Bostwick DG, i-Cheng L. Neoplasms ye-prostate. Ku: Cheng L, MacLennan GT, Bostwick DG, ama-eds. I-Urologyic Pathology Yokuhlinzwa. Umhla wesi-4. IPhiladelphia, PA: Elsevier; 2020: isahluko 9.

U-Epstein JI. Izifo ze-prostatic neoplasia.Ku: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, ama-eds. ICampbell-Walsh-Wein Urology. Umhla ka-12. IPhiladelphia, PA: Elsevier; 2021: isahluko 151.

Iwebhusayithi yeNational Cancer Institute. Ukwelashwa komdlavuza we-Prostate (PDQ) - inguqulo yezempilo. www.cancer.gov/types/prostate/hp/prostate-treatment-pdq#_2097_toc. Kubuyekezwe uJulayi 22, 2020. Kufinyelelwe ngo-Agasti 10, 2020.

• Umdlavuza Wendlala Yesinye