I-Ganglioneuroma

I-Ganglioneuroma iyisigaxa sesimiso sezinzwa ezizimele.

Ama-Ganglioneuromas yizicubu ezingavamile ezivame ukuqala kumaseli ezinzwa ezizimele. Izinzwa ezizimele zilawula imisebenzi yomzimba efana nomfutho wegazi, ukushaya kwenhliziyo, ukujuluka, ukuphuma kwamathumbu nesinye, nokugaya ukudla. Izicubu zivame ukungabi nomdlavuza (ubungozi).

I-Ganglioneuromas ivame ukuvela kubantu abaneminyaka engaphezu kwengu-10 ubudala. Zikhula kancane, futhi zingakhipha amakhemikhali noma ama-hormone athile.

Azikho izinto eziyingozi ezaziwayo. Kodwa-ke, izicubu zingahle zihlotshaniswe nezinkinga ezithile zofuzo, ezinjenge-neurofibromatosis type 1.

I-ganglioneuroma ngokuvamile ayibangeli zimpawu. Isimila sitholakala kuphela lapho umuntu ehlolwa noma elashelwa esinye isimo.

Izimpawu zincike lapho kutholakala khona isimila nohlobo lwamakhemikhali asikhiphayo.

Uma isimila sisendaweni yesifuba (i-mediastinum), izimpawu zingafaka:

• Ubunzima bokuphefumula
• Ubuhlungu besifuba
• Ukuminyaniswa kwe-windpipe (trachea)

Uma isimila siphansi phansi esiswini endaweni ebizwa ngokuthi isikhala se-retroperitoneal, izimpawu zingafaka:

• Ubuhlungu besisu
• Ukuqhakaza

Uma isimila siseduze nentambo yomgogodla, singadala:

• Ukucindezelwa kwentambo yomgogodla, okuholela ezinhlungwini nasekulahlekelweni kwamandla noma ekuzweni imilenze, izingalo, noma zombili
• Ukukhubazeka komqolo

Lezi zicubu zingakhiqiza ama-hormone athile, angadala lezi zimpawu ezilandelayo:

• Uhudo
• I-clitoris ekhulisiwe (abesifazane)
• Umfutho wegazi ophezulu
• Izinwele zomzimba ezandisiwe
• Ukujuluka

Ukuhlolwa okuhle kakhulu ukukhomba i-ganglioneuroma yile:

• Ukuhlolwa kwe-CT kwesifuba, kwesisu, kanye nesinqe
• Ukuskena iMRI kwesifuba nesisu
• I-Ultrasound yesisu noma okhalo

Ukuhlolwa kwegazi nomchamo kungenziwa ukuthola ukuthi isimila sikhiqiza yini ama-hormone noma amanye amakhemikhali.

Ukususwa kwe-biopsy noma okuphelele kwe-tumor kungadingeka ukuze kuqinisekiswe ukuxilongwa.

Ukwelashwa kuhilela ukuhlinzwa ukuze kususwe isimila (uma sibangela izimpawu).

Iningi lama-ganglioneuromas alinomdlavuza. Umphumela olindelwe uvame ukuba muhle.

I-ganglioneuroma ingaba nomdlavuza bese isakazekela kwezinye izindawo. Kungabuye kubuye ngemuva kokususwa.

Uma isimila sesibe khona isikhathi eside futhi sicindezele umgogodla noma senza ezinye izimpawu, ukuhlinzwa ukuze kususwe isimila kungenzeka kungawuphenduli umonakalo. Ukucindezelwa komgogodla kungaholela ekulahlekelweni ukunyakaza (ukukhubazeka), ikakhulukazi uma imbangela ingatholakali ngokushesha.

Ukuhlinzwa ukukhipha isimila nakho kungaholela ezinkingeni kwezinye izimo. Ezimweni ezingavamile, izinkinga ngenxa yokucindezelwa zingenzeka ngisho nangemva kokususwa kwesimila.

Shayela umhlinzeki wakho wezokunakekelwa kwezempilo uma wena noma ingane yakho unezimpawu ezingabangelwa lolu hlobo lwesimila.

• Isistimu yezinzwa emaphakathi nesistimu yezinzwa ezungezayo

IGoldblum JR, i-Folpe AL, i-Weiss SW. Izicubu ze-Benign zezinzwa zomzimba. Ku: Goldblum JR, Folpe AL, Weiss SW, ama-eds. Izicubu ze-Enzinger ne-Weiss's Tissue Tumors. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2020: isahluko 26.

UKaidar-Person O, Zagar T, Haithcock BE, Weiss J. Izifo ze-pleura ne-mediastinum. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, abahleli. I-Abeloff’s Clinical Oncology. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2020: isahluko 70.