I-Autosomal ephezulu

I-Autosomal ephezulu ingenye yezindlela eziningi lapho isici noma ukuphazamiseka kungadluliswa emindenini.

Esimweni esibucayi se-autosomal, uma uthola isakhi esingajwayelekile kumzali oyedwa kuphela, ungathola lesi sifo. Imvamisa, omunye wabazali naye angaba nalesi sifo.

Ukuthola ifa lesifo, isimo, noma isici kuncike ohlotsheni lwe-chromosome ethintekile (i-nonsex noma i-chromosome yezocansi). Kuya futhi ngokuthi ngabe le mfanelo iyabusa noma ihlehlisile.

Isakhi sofuzo esisodwa esingajwayelekile kwelinye lama-chromosomes angama-22 okuqala we-nonsex (autosomal) avela komunye umzali angadala ukuphazamiseka kwe-autosomal.

Ifa eliqavile lisho ukuthi ufuzo olungavamile oluvela kumzali oyedwa lungadala izifo. Lokhu kwenzeka noma ngabe ufuzo olufanayo oluvela komunye umzali lujwayelekile. Kubusa isakhi esingajwayelekile.

Lesi sifo singenzeka futhi njengesimo esisha enganeni lapho kungekho mzali enofuzo olungajwayelekile.

Umzali onesimo esibusayo se-autosomal unethuba elingama-50% lokuba nengane enalesi sifo. Lokhu kuyiqiniso ngokukhulelwa ngakunye.

Kusho ukuthi ubungozi bengane ngayinye kulesi sifo abuxhomekile ekutheni ingane yakubo inaso yini lesi sifo.

Izingane ezingalitholi njengelifa ufuzo olungajwayelekile ngeke zikhule noma zisidlulise lesi sifo.

Uma othile kutholakala ukuthi unesifo esivelele se-autosomal, abazali babo kufanele futhi bahlolwe uhlobo olungajwayelekile.

Izibonelo zokuphazamiseka okukhulu kwe-autosomal zifaka iMarfan syndrome nohlobo lwe-neurofibromatosis 1.

Ifa - i-autosomal ephezulu; I-Genetics - i-autosomal ephezulu

• Izakhi zofuzo ezihamba phambili ze-Autosomal

UNussbaum RL, McInnes RR, uWillard HF. Amaphethini wefa elilodwa lohlobo olulodwa. Ku: Nussbaum RL, McInnes RR, Willard HF, ama-eds. I-Thompson & Thompson Genetics kwezokwelapha. Umhlaka 8. IPhiladelphia, PA: Elsevier; 2016: isahluko 7.

UScott DA, uLee B. Amaphethini wokudluliswa kofuzo. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhla ka-21 ed ..Philadelphia, PA: Elsevier; 2020: isahluko 97.