I-Apolipoprotein B100
I-Apolipoprotein B100 (apoB100) yiprotheni ebamba iqhaza ekunyakaziseni i-cholesterol emzimbeni wakho. Kuyindlela ye-low density lipoprotein (LDL).
Ukuguqulwa kwezinguquko (izinguquko) ku-apoB100 kungadala isimo esibizwa nge-hypercholesterolemia yomndeni. Lolu uhlobo lwe-cholesterol ephezulu edluliselwa emindenini (ezuzwe njengefa).
Lo mbhalo ukhuluma ngokuhlolwa okusetshenzisiwe ukukala izinga le-apoB100 egazini.
Kudingeka isampula yegazi.
Umhlinzeki wakho wezokunakekelwa kwempilo angakutshela ukuthi ungadli noma uphuze noma yini amahora amane kuya kwayisithupha ngaphambi kokuhlolwa.
Lapho inaliti ifakwa ukudonsa igazi, ungezwa ubuhlungu obulinganiselayo, noma umuzwa ohlabayo noma olumayo kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile.
Ngokuvamile, lokhu kuhlolwa kwenziwa ukusiza ukuthola imbangela noma uhlobo oluthile lwe-cholesterol ephezulu yegazi. Akucaci ukuthi imininingwane iyasiza yini ekwenzeni ngcono ukwelashwa. Ngenxa yalokhu, izinkampani eziningi zomshuwalense wezempilo AZIKHOKHELI isivivinyo. Uma ungenayo i-cholesterol ephezulu noma isifo senhliziyo, lokhu kuhlolwa kungenzeka kunganconyelwa wena.
Ububanzi obujwayelekile bucishe bube ngama-50 kuye ku-150 mg / dL.
Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye ama-laboratories asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezahlukene. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.
Umphumela ongajwayelekile ungasho ukuthi unamazinga aphezulu e-lipid (amafutha) egazini lakho. Igama lezokwelapha lalokhu yi-hyperlipidemia.
Ezinye izinkinga ezingahle zihlotshaniswe namazinga aphezulu e-apoB100 afaka isifo se-atherosclerotic vascular ezifana ne-angina pectoris (ubuhlungu besifuba obenzeka ngomsebenzi noma ukucindezeleka) nokuhlaselwa yinhliziyo.
Izingozi ezixhunywe ekudonsweni kwegazi zincane, kepha zingafaka:
- Ukopha ngokweqile
- Ukuquleka noma uzizwe unekhanda elincane
- I-hematoma (i-blood buildup ngaphansi kwesikhumba)
- Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)
- Ukubhoboza okuningi ukuthola imithambo
Izilinganiso ze-Apolipoprotein zinganikeza imininingwane eminingi ngengozi yesifo senhliziyo, kepha inani elengeziwe lalesi sivivinyo ngaphezu kwephaneli ye-lipid alaziwa.
I-ApoB100; I-Apoprotein B100; I-Hypercholesterolemia - apolipoprotein B100
- Ukuhlolwa kwegazi
UFazio S, uLinton MF. Ukulawulwa nokususwa kwe-apolipoprotein B-equkethe i-lipoproteins. Ku: Ballantyne CM, ed. I-Clinical Lipidology: Umngane Wesifo Senhliziyo SaseBraunwald. Okwesibili. IPhiladelphia, PA: Elsevier; 2015: isahluko 2.
UGenest J, ukuphazamiseka kweLibby P. Lipoprotein nesifo senhliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2019: isahluko 48.
I-Remaley AT, i-Daypring TD, i-Warnick GR. Ama-lipids, ama-lipoprotein, ama-apolipoprotein, nezinye izinto ezinobungozi benhliziyo. Ku: Rifai N, ed. I-Tietz Textbook ye-Clinical Chemistry kanye ne-Molecular Diagnostics. Umhlaka 6. ISt Louis, MO: Elsevier; 2018: isahluko 34.
URobinson JG. Ukuphazamiseka kwe-lipid metabolism. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 195.