I-Apolipoprotein CII

I-Apolipoprotein CII (apoCII) yiprotheni etholakala ezinhlayiyweni ezinkulu zamafutha ezithathwa yipheshana lesisu. Iphinde itholakale ku-low low density lipoprotein (VLDL), eyakhiwa kakhulu ngama-triglycerides (uhlobo lwamafutha egazini lakho).

Lo mbhalo ukhuluma ngokuhlolwa okusetshenziselwa ukubheka i-apoCII kusampula yegazi lakho.

Kudingeka isampula yegazi.

Ungatshelwa ukuthi ungadli noma uphuze noma yini amahora amane kuya kwayisithupha ngaphambi kokuhlolwa.

Lapho inaliti ifakwa ukudonsa igazi, ungezwa ubuhlungu obuthile, noma ukubhoboza noma ukuluma kuphela. Ngemuva kwalokho, kungahle kube nokushaywa lapho inaliti yafakwa khona.

Izilinganiso ze-ApoCII zingasiza ekunqumeni uhlobo noma imbangela yamafutha aphezulu egazi. Akucaci noma imiphumela yokuhlola iyayithuthukisa yini imishanguzo. Ngenxa yalokhu, izinkampani eziningi zomshuwalense wezempilo ngeke zikhokhele isivivinyo. Uma ungenayo i-cholesterol ephezulu noma isifo senhliziyo noma umlando womndeni walezi zimo, lokhu kuhlolwa kungenzeka kunganconyelwa wena.

Ububanzi obujwayelekile bungu-3 kuye ku-5 mg / dL. Kodwa-ke, imiphumela ye-apoCII ivame ukubikwa njengamanje noma engekho.

Izibonelo ezingenhla yizilinganiso ezijwayelekile zemiphumela yalezi zivivinyo. Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Amazinga aphezulu e-apoCII angabangelwa umlando womndeni wokushoda kwe-lipoprotein lipase. Lesi yisimo lapho umzimba ungehlukanisi khona amafutha ngokujwayelekile.

Amazinga we-ApoCII ayabonakala nakubantu abanesimo esingajwayelekile esibizwa ngokushoda kwe-apoprotein CII yomndeni. Lokhu kubangela i-chylomicronemia syndrome, esinye isimo lapho umzimba ungadilizi amafutha ngokujwayelekile.

Izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Izilinganiso ze-Apolipoprotein zinganikeza imininingwane eminingi ngengozi yesifo senhliziyo, kepha inani elengeziwe lalesi sivivinyo ngaphezu kwephaneli ye-lipid alaziwa.

I-ApoCII; I-Apoprotein CII; I-ApoC2; Ukushoda kwe-lipoprotein lipase - apolipoprotein CII; I-Chylomicronemia syndrome - i-apolipoprotein CII

• Ukuhlolwa kwegazi

UChen X, uZhou L, uHussain MM. I-Lipids ne-dyslipoproteinemia. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 17.

UGenest J, ukuphazamiseka kweLibby P. Lipoprotein nesifo senhliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2019: isahluko 48.

I-Remaley AT, i-Daypring TD, i-Warnick GR. Ama-lipids, ama-lipoprotein, ama-apolipoprotein, nezinye izinto ezinobungozi benhliziyo. Ku: Rifai N, ed. I-Tietz Textbook ye-Clinical Chemistry kanye ne-Molecular Diagnostics. Umhlaka 6. ISt Louis, MO: Elsevier; 2018: isahluko 34.

URobinson JG. Ukuphazamiseka kwe-lipid metabolism. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 195.