Isilingo se-Factor IX

Ukuhlolwa kwe-factor IX ukuhlolwa kwegazi okulinganisa umsebenzi we-factor IX. Lokhu kungenye yamaprotheni asiza ihlule legazi.

Kudingeka isampula yegazi.

Kungase kudingeke ukuthi uyeke ukuthatha imithi ethile ngaphambi kwalokhu kuhlolwa. Umhlinzeki wakho wokunakekelwa kwezempilo uzokutshela ukuthi iziphi.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlola kusetshenziselwa ukuthola imbangela yokopha kakhulu (kwehle ukunqamuka kwegazi). Noma, kungahle ku-odelwe uma ilungu lomndeni laziwa ukuthi line-hemophilia B. Ukuhlolwa kungenziwa futhi ukubona ukuthi isebenza kanjani kahle i-hemophilia B.

Inani elijwayelekile lingu-50% kuya ku-200% wokulawulwa kwelabhorethri noma inani lesethenjwa.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izibonelo ezingenhla zibonisa izilinganiso ezivamile zemiphumela yalezi zivivinyo.

Umsebenzi we-IX owehlisiwe ungahle uhlobane no:

• I-Hemophilia B (ukuphazamiseka kokopha okubangelwa ukuntuleka kwegazi lokuvala igazi i-IX)
• Ukuphazamiseka lapho amaprotheni alawula ukujiya kwegazi eba ngaphezulu kokusebenzayo (kusatshalaliswa i-intravascular coagulation)
• I-fat malabsorption (hhayi ukumunca amafutha anele ekudleni kwakho)
• Isifo sesibindi (njenge-cirrhosis)
• Ukushoda kukaVitamin K
• Ukuthatha izinciphisi zegazi

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo iyehluka ngobukhulu ukusuka komunye umuntu iye komunye, futhi kusukela kolunye uhlangothi lomzimba kuye kolunye. Ukuthola isampula yegazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Lokhu kuhlolwa kuvame ukwenziwa kubantu abanezinkinga zokopha. Ingozi yokopha ngokweqile ingaphezulu kancane kwabantu abanenkinga yokopha.

Ukuhlolwa kwesici sikaKhisimusi; Isici se-Serum IX; Isici se-hemophilic B; Ingxenye ye-Plasma thromboplastin; PTC

UCarcao M, Moorehead P, uLillicrap D.Hemophilia A noB B. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 135.

IChernecky CC, iBerger BJ. I-Factor IX (isici sikaKhisimusi, isici se-hemophilic B, ingxenye ye-plasma thromboplastin, i-PTC) - igazi. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 505-506.

Ukuhlolwa kwelabhorethri yezifo ze-hemostatic ne-thrombotic. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 129.