L-Tryptophan

-Delile

• Kungenzeka kungasebenzi ku ...
• Ubufakazi obanele bokukala ukusebenza kwe ...
• Ukuqapha okukhethekile nezixwayiso:

I-tryptophan iyi-amino acid. Ama-amino acid ayizakhi zokwakha amaprotheni. I-tryptophan ibizwa nge-amino acid "ebalulekile" ngoba umzimba awukwazi ukuzenzela wedwa. Kumele itholakale ekudleni. I-tryptophan idliwa njengengxenye yokudla futhi ingatholakala ekudleni okuqukethe amaprotheni.

Abantu basebenzisa i-L-tryptophan ukuthola izimpawu ezinzima ze-PMS (premenstrual dysphoric disorder noma i-PMDD), ukusebenza kwezemidlalo, ukudangala, ukuqwasha, nezinye izimo eziningi, kepha abukho ubufakazi obuhle besayensi bokusekela lokhu kusetshenziswa.

Imibhalo Yemvelo Yemininingwane Ephelele ukukala ukusebenza ngokuncike ebufakazini besayensi ngokwesilinganiso esilandelayo: Okusebenzayo, Okungenzeka Kusebenze, Okungenzeka Kusebenze, Okungenzeka Kungasebenzi, Cishe Okungaphumeleli, Ukungasebenzi, Nobufakazi Obunganele Bokulinganisa.

Izilinganiso zokusebenza ze L-TRYPTOPHAN zimi kanje:

Kungenzeka kungasebenzi ku ...

• Ukugaya amazinyo (bruxism). Ukuthatha i-L-tryptophan ngomlomo akusizi ukwelapha ukugaya amazinyo.
• Isimo esidala ubuhlungu bemisipha obuqhubekayo (i-myofascial pain syndrome). Ukuthatha i-L-tryptophan ngomlomo akusizi ukunciphisa lolu hlobo lobuhlungu.

Ubufakazi obanele bokukala ukusebenza kwe ...

• Ukusebenza kwezemidlalo. Olunye ucwaningo lubonisa ukuthi ukuthatha i-L-tryptophan izinsuku ezintathu ngaphambi kokuzivocavoca kungathuthukisa amandla ngesikhathi sokuzivocavoca. Lokhu kuthuthukiswa kwamandla kusiza ukukhuphula ibanga umgijimi angalihamba ngesikhathi esifanayo. Kodwa olunye ucwaningo lwakuqala lukhombisa ukuthi ukuthatha i-L-tryptophan ngesikhathi sokuzivocavoca akukuthuthukisi ukukhuthazela ngesikhathi sokuzivocavoca ngebhayisikili. Izizathu zemiphumela ephikisanayo azicaci. Kungenzeka ukuthi i-L-tryptophan ithuthukise ezinye izindlela zekhono lezemidlalo kepha hhayi ezinye. Ngakolunye uhlangothi, i-L-tryptophan ingadinga ukuthathwa izinsuku ezimbalwa ngaphambi kokuzivocavoca ukuze ubone noma yikuphi ukuzuza.
• Ukunakwa kokushoda-i-hyperactivity disorder (ADHD). Kunobunye ubufakazi bokuthi amazinga e-L-tryptophan aphansi ezinganeni ezine-ADHD. Kepha ukuthatha izengezo ze-L-tryptophan akubonakali kuthuthukisa izimpawu ze-ADHD.
• Ukucindezeleka. Ucwaningo lokuqala lukhombisa ukuthi i-L-tryptophan ingahle ithuthukise ukusebenza kwemithi ejwayelekile yokudangala.
• I-Fibromyalgia. Ucwaningo lokuqala lukhombisa ukuthi ukufaka ama-walnuts ekudleni kwaseMedithera ukuhlinzeka nge-L-tryptophan ne-magnesium eyengeziwe kungathuthukisa ukukhathazeka nezinye izimpawu ze-fibromyalgia.
• Ukutheleleka kokugaya ukudla okungaholela ezilondeni (Helicobacter pylori noma H. ​​pylori). Ucwaningo lukhombisa ukuthi ukuthatha i-L-tryptophan ngokuhambisana nemithi yesilonda i-omeprazole kuthuthukisa amazinga okuphulukiswa kwezilonda uma kuqhathaniswa nokuthatha i-omeprazole iyodwa.
• Ukuqwasha. Ukuthatha i-L-tryptophan kunganciphisa isikhathi esithathayo ukulala nokuthuthukisa imizwa kubantu abaphilile abanezinkinga zokulala. Ukuthatha i-L-tryptophan nakho kungathuthukisa ukulala kubantu abanezinkinga zokulala ezihlobene nokuhoxa kwezidakamizwa ezingekho emthethweni.
• Migraine. Ucwaningo lwangaphambilini luthole ukuthi ukuba namazinga aphansi e-L-tryptophan ekudleni kuxhumene nengozi eyengeziwe ye-migraine.
• Izimpawu ezinzima ze-PMS (i-premenstrual dysphoric disorder noma i-PMDD). Ukuthatha amagremu ama-6 we-L-tryptophan ngosuku kubonakala kunciphisa ukuguquguquka kwemizwelo, ukungezwani, nokucasuka kwabesifazane abane-PMDD.
• Ukudangala kwesizini (ukuphazamiseka kwesizini noma i-SAD). Ucwaningo lokuqala lubonisa ukuthi i-L-tryptophan ingasiza ku-SAD.
• Inkinga yokulala lapho abantu beyeka okwesikhashana ukuphefumula ngenkathi belele (i-apnea yokulala). Kunobunye ubufakazi bokuthi ukuthatha i-L-tryptophan kunganciphisa iziqephu kwabanye abantu abanesimo esithile salesi simo, esibizwa ngokuthi yi-obstructive sleep apnea (OSA).
• Ukuyeka ukubhema. Ukuthatha i-L-tryptophan kanye nokwelashwa okuvamile kungasiza abanye abantu ukuthi bayeke ukubhema.
• Ukukhathazeka.
• Nciphisa amakhono okukhumbula nawokucabanga kubantu asebekhulile okungaphezu kokujwayelekile ngeminyaka yabo.
• Gout.
• I-Premenstrual syndrome (i-PMS).
• I-Tourette syndrome.
• Ezinye izimo.

Kudingeka ubufakazi obuningi ukukala i-L-tryptophan yalokhu kusetshenziswa.

I-L-tryptophan itholakala ngokwemvelo kumaprotheni ezilwane nezitshalo. I-tryptophan ibhekwa njenge-amino acid ebalulekile ngoba imizimba yethu ayikwazi ukuyenza. Kubalulekile ekuthuthukiseni nasekusebenzeni kwezitho eziningi emzimbeni. Ngemuva kokumunca i-L-tryptophan ekudleni, imizimba yethu iguqula enye yayo ibe yi-5-HTP (5-hyrdoxytryptophan), bese i-serotonin. Imizimba yethu futhi iguqula enye i-L-tryptophan ibe yi-niacin (uvithamini B3). I-Serotonin iyi-hormone ehambisa amasignali phakathi kwamangqamuzana ezinzwa. Kubangela nokuthi imithambo yegazi inciphe. Izinguquko ezingeni le-serotonin ebuchosheni zingashintsha imizwa. Lapho ithathwa ngomlomo: L-tryptophan kuyinto OKUNGENZEKA UKUPHEPHA lapho kuthathwa ngomlomo, isikhathi esifushane. I-tryptophan ingadala imiphumela emibi efana nokushiswa yinhliziyo, ubuhlungu besisu, ukubopha kanye negesi, isicanucanu, ukuhlanza, isifo sohudo, kanye nokulahlekelwa isifiso sokudla. Kungadala nekhanda, ikhanda elikhanyayo, ukozela, umlomo owomile, ukufiphala okubukwayo, ubuthakathaka bemisipha, nezinkinga zocansi kwabanye abantu. Ngo-1989, i-L-tryptophan yayixhunyaniswe nemibiko engaphezu kuka-1500 ye-eosinophilia-myalgia syndrome (EMS) kanye nokufa kwabantu abangama-37. I-EMS yisimo sezinzwa esibangela izimpawu eziningi ezahlukene. Lezi zimpawu zivame ukuthuthuka ngokuhamba kwesikhathi, kepha abanye abantu bangase babe nezimpawu kuze kube yiminyaka engu-2 ngemuva kokuthuthukisa i-EMS. Ngo-1990, uL-tryptophan wakhunjulwa emakethe ngenxa yalokhu kukhathazeka ngokuphepha. Isizathu ngqo se-EMS ezigulini ezithatha i-L-tryptophan asaziwa, kepha obunye ubufakazi busikisela ukuthi kungenxa yokungcola. Cishe i-95% yawo wonke amacala e-EMS alandelwe ku-L-tryptophan akhiqizwa ngumkhiqizi oyedwa eJapan. Njengamanje, ngaphansi kwe-Dietary Supplement Health and Education Act (DSHEA) ka-1994, i-L-tryptophan iyatholakala futhi imakethwa njengesengezo sokudla e-United States.

Alukho ulwazi olwanele oluthembekile lokwazi ukuthi i-L-tryptophan iphephile yini uma ithathwa ngomlomo isikhathi eside.

Ukuqapha okukhethekile nezixwayiso:

Ukukhulelwa nokuncelisa ibele: L-tryptophan kuyinto Cishe UNGAPHEPHILE ekukhulelweni ngoba kungalimaza ingane engakazalwa. Alukho ulwazi olwanele olunokwethenjelwa lokwazi ukuthi ngabe i-L-tryptophan iphephile yini ukuyisebenzisa lapho uncelisa. Hlala ohlangothini oluphephile futhi ugweme i-L-tryptophan ngesikhathi sokukhulelwa nokuncelisa.

Okukhulu

Ungathathi le nhlanganisela.

Imithi yokudambisa (i-CNS depressants)

I-tryptophan ingadala ukulala nokuzela. Imithi ebanga ubuthongo ibizwa ngokuthi yimithi yokuthambisa. Ukuthatha i-L-tryptophan kanye nemithi yokwelapha kungadala ukulala kakhulu.

Eminye imishanguzo yokuthambisa ibandakanya i-clonazepam (iKlonopin), i-lorazepam (Ativan), i-phenobarbital (iDonnatal), i-zolpidem (i-Ambien), neminye.

Maphakathi

Qaphela ngale nhlanganisela.

Izidakamizwa zeSerotonergic

I-tryptophan inyusa ikhemikhali ebuchosheni ebizwa nge-serotonin. Eminye imithi ibuye inyuse i-serotonin. Ukuthatha i-L-tryptophan kanye nale mithi kungakhuphula i-serotonin kakhulu. Lokhu kungadala imiphumela emibi kakhulu kubandakanya ikhanda elibuhlungu, izinkinga zenhliziyo, ukuqhaqhazela, ukudideka nokukhathazeka.

Eminye yale mithi ifaka i-fluoxetine (Prozac), i-paroxetine (i-Paxil), i-sertraline (i-Zoloft), i-amitriptyline (i-Elavil), i-clomipramine (i-Anafranil), i-imipramine (i-Tofranil), i-sumatriptan (Imitrex), i-zolmitriptan (i-Zomig), i-rizatriptan i-methadone (i-Dolophine), i-tramadol (i-Ultram), nezinye eziningi.

Amakhambi kanye nezithasiselo ezinezakhiwo zokuthambisa

I-L-tryptophan ingadala ukozela nokuphumula. Ukuyisebenzisa kanye namanye amakhambi nezengezo ezinemiphumela yokudambisa umzimba kungadala ukozela okukhulu. Amanye alawa makhambi nezithako ahlanganisa i-5-HTP, i-calamus, i-poppy yaseCalifornia, i-catnip, i-hops, i-dogwood yaseJamican, i-kava, iSt John's wort, i-skullcap, i-valerian, i-yerba mansa, nezinye.

Amakhambi nezengezo ezinezakhiwo ze-serotonergic

I-L-tryptophan ibonakala inyusa izinga le-serotonin, i-hormone ehambisa amasignali phakathi kwamangqamuzana ezinzwa futhi athinte imizwa. Kukhona ukukhathazeka ngokuthi ukuyisebenzisa ngamanye amakhambi nezithako ezengeza i-serotonin, kungakhuphula imiphumela kanye nemiphumela emibi yalawo makhambi nezengezo. Ezinye zazo zifaka i-5-HTP, i-Hawaiian baby woodrose, ne-S-adenosylmethionine (SAMe).

Isibungu iSt

Ukuhlanganisa i-L-tryptophan ne-St. John's wort kungakhuphula ubungozi be-serotonin syndrome, isimo esingaba yingozi esenzeka lapho kune-serotonin eningi kakhulu emzimbeni. Kunombiko we-serotonin syndrome esigulini esithathe i-L-tryptophan kanye namanani aphezulu we-wort yaseSt.

Akukho ukuxhumana okwaziwayo nokudla.

Eminye imikhiqizo yokwengeza yokudla kungenzeka ingabhalisi i-L-tryptophan ngokuhlukile kwilebula. Esikhundleni salokho, kungahle kubhalwe ngaphansi kwe-niacin. I-Niacin ilinganiswa ngokulingana kwe-niacin (NE). I-60 mg ye-L-tryptophan iyefana ne-1 mg NE.

Umthamo ofanele we-L-tryptophan uncike ezicini eziningana ezifana nobudala bomsebenzisi, impilo, kanye nezinye izimo eziningana. Ngalesi sikhathi alukho ulwazi olwanele lwesayensi lokunquma uhla olufanele lwamanani we-L-tryptophan. Khumbula ukuthi imikhiqizo yemvelo ayihlali iphephile njalo futhi imithamo ingabaluleka. Qiniseka ukuthi ulandela izinkomba ezifanele kumalebula womkhiqizo futhi uthintane nosokhemisi wakho noma udokotela noma omunye uchwepheshe wezokunakekelwa kwempilo ngaphambi kokusebenzisa. L-Triptofano, L-Trypt, L-2-amino-3- (indole-3-yl) propionic acid, L-Tryptophane, Tryptophan.

Ukuze ufunde kabanzi ngokuthi le ndatshana ibhalwe kanjani, sicela ubheke ifayela le- Imibhalo Yemvelo Yemininingwane Ephelele indlela.

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