ICyclosporine

-Delile

• Ukuthatha noma yiluphi uhlobo lwesisombululo somlomo, landela lezi zinyathelo:
• Ngaphambi kokuthatha i-cyclosporine noma i-cyclosporine (modified),
• I-Cyclosporine ne-cyclosporine (modified) kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

ICyclosporine itholakala ngendlela ebhalwe ngayo futhi njengomunye umkhiqizo osushintshiwe (washintshwa) ukuze umuthi ungene kahle emzimbeni. I-cyclosporine yangempela ne-cyclosporine (iguquliwe) ifakwa ngumzimba ngamanani ahlukile, ngakho-ke awunakufakwa omunye komunye. Thatha kuphela uhlobo lwe-cyclosporine olunikezwe udokotela wakho. Lapho udokotela wakho ekunikeza incwadi ebhaliwe, hlola ukuqinisekisa ukuthi ulucacisile uhlobo lwe-cyclosporine okufanele uluthole. Ngaso sonke isikhathi lapho ugcwaliswa ngudokotela wakho, bheka igama lomkhiqizo eliphrintiwe kwilebula yakho kadokotela ukuze uqiniseke ukuthi uthole uhlobo olufanayo lwe-cyclosporine. Khuluma nosokhemisi wakho uma igama lomkhiqizo lingaziwa noma awunasiqiniseko sokuthi uthole uhlobo olufanele lwe-cyclosporine.

Ukuthatha i-cyclosporine noma i-cyclosporine (kuguquliwe) kungakhuphula ubungozi bokuthi uzoba nokutheleleka noma umdlavuza, ikakhulukazi i-lymphoma (umdlavuza wengxenye yamasosha omzimba) noma umdlavuza wesikhumba. Le ngozi ingaphakama uma uthatha i-cyclosporine noma i-cyclosporine (iguqulwe) neminye imishanguzo eyehlisa ukusebenza kwamasosha omzimba njenge-azathioprine (Imuran), i-chemotherapy yomdlavuza, i-methotrexate (i-Rheumatrex), i-sirolimus (i-Rapamune), ne-tacrolimus (i-Prograf) . Tshela udokotela wakho uma ngabe uthatha noma iyiphi yale mithi, nokuthi ngabe uke waba nanoma iluphi uhlobo lomdlavuza noma wake waba nalo. Ukuze wehlise amathuba okuba nomdlavuza wesikhumba, hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, izibuko zelanga, nesikhumba selanga ngesikhathi sokwelashwa kwakho. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umphimbo obuhlungu, umkhuhlane, ukubanda, nezinye izimpawu zokutheleleka; izimpawu ezinjengomkhuhlane; ukukhwehlela; ubunzima bokuchama; ubuhlungu lapho uchama; indawo ebomvu, ephakanyisiwe, noma evuvukile esikhunjeni; izilonda ezintsha noma ukushintsha kombala esikhunjeni; izigaxa noma uquqaba noma kuphi emzimbeni wakho; ukujuluka ebusuku; izindlala ezivuvukile entanyeni, emakhwapheni, noma emgodini; ukuphefumula kanzima; ubuhlungu besifuba; ubuthakathaka noma ukukhathala okungapheli; noma ubuhlungu, ukuvuvukala, noma ukugcwala esiswini.

I-Cyclosporine ne-cyclosporine (iguqulwe) ingadala umfutho wegazi ophezulu kanye nokulimala kwezinso. Tshela udokotela wakho uma uke waba nomfutho wegazi ophakeme noma isifo sezinso. Phinda utshele udokotela wakho uma uthatha noma iyiphi yale mithi elandelayo: i-amphotericin B (i-Amphotec, iFungizone); i-cimetidine (Tagamet); i-ciprofloxacin (Cipro); colchicine; i-fenofibrate (i-Antara, iLipophen, iTricor); gemfibrozil (Lopid); i-gentamicin; ketoconazole (Nizoral); i-melphalan (Alkeran); izidakamizwa ezingezona ukuvuvukala ezifana ne-diclofenac (Cataflam, Voltaren), naproxen (Aleve, Naprosyn), ne-sulindac (Clinoril); i-ranitidine (iZantac); i-tobramycin (Tobi); i-trimethoprim ene-sulfamethoxazole (Bactrim, Septra); kanye ne-vancomycin (Vancocin). Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isiyezi; ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi; ukushesha, ukuphefumula okungajulile; isicanucanu; noma ukushaya kwenhliziyo okungajwayelekile.

Uma une-psoriasis, tshela udokotela wakho ngazo zonke izindlela zokwelapha i-psoriasis nemithi oyisebenzisayo noma oyisebenzise esikhathini esedlule. Ingcuphe yokuthi uzoba nomdlavuza wesikhumba inkulu uma uke welashwa nge-PUVA (psoralen ne-UVA; ukwelashwa kwe-psoriasis ehlanganisa umuthi womlomo noma wezindaba nokuchayeka ku-ultraviolet A light); i-methotrexate (Rheumatrex) noma eminye imithi ecindezela amasosha omzimba; I-UVB (ukuvezwa kokukhanya kwe-ultraviolet B ukwelapha i-psoriasis); itiyela lamalahle; noma ukwelashwa ngemisebe. Akufanele welashwe nge-PUVA, i-UVB, noma imishanguzo ecindezela amasosha omzimba ngenkathi uthatha i-cyclosporine (modified) ukwelapha i-psoriasis.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-cyclosporine noma i-cyclosporine (modified).

I-Cyclosporine ne-cyclosporine (iguquliwe) isetshenziswa neminye imithi ukuvimbela ukwenqatshwa kokufakelwa (ukuhlaselwa kwesitho esifakelwe amasosha omzimba womuntu owathola isitho) kubantu abathole ukufakelwa izinso, isibindi, nenhliziyo. I-Cyclosporine (modified) nayo isetshenziswa yodwa noma nge-methotrexate (Rheumatrex) ukwelapha izimpawu zesifo samathambo (isifo samathambo esibangelwa ukuvuvukala kolwelwesi lwamalunga) ezigulini ezinezimpawu zazo ezingazange zikhululwe yi-methotrexate yodwa. I-Cyclosporine (modified) isetshenziselwa ukwelapha i-psoriasis (isifo sesikhumba lapho kwakhiwa khona amabala abomvu, anezikhala ezindaweni ezithile zomzimba) ezigulini ezithile ezingakasizwa ngezinye izindlela zokwelapha. I-Cyclosporine ne-cyclosporine (modified) basesigabeni semithi ebizwa ngama-immunosuppressants. Basebenza ngokunciphisa umsebenzi wamasosha omzimba.

I-Cyclosporine ne-cyclosporine (iguqulwe) zombili ziza njenge-capsule nesisombululo (uketshezi) ukuthatha ngomlomo. I-cyclosporine ivame ukuthathwa kanye ngosuku. I-Cyclosporine (modified) ivame ukuthathwa kabili ngosuku. Kubalulekile ukuthatha zombili izinhlobo ze-cyclosporine esimisweni esijwayelekile. Thatha i-cyclosporine noma i-cyclosporine (elungisiwe) ngasikhathi sinye (ama) ngosuku ngalunye, bese uvumela isikhathi esilinganayo phakathi kwamanani nokudla nsuku zonke.Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-cyclosporine noma i-cyclosporine (iguqulwe) njengoba nje kuqondisiwe. Ungathathi imishanguzo cishe emincane noma uyiphuze kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho mhlawumbe uzolungisa umthamo wakho we-cyclosporine noma i-cyclosporine (eguquliwe) ngesikhathi sokwelashwa kwakho. Uma uthatha noma yiluphi uhlobo lwe-cyclosporine ukuvimbela ukwenqatshwa kokufakelwa, udokotela wakho mhlawumbe uzokuqala ngomthamo omkhulu womuthi futhi anciphise umthamo wakho kancane kancane. Uma uthatha i-cyclosporine (modified) ukwelapha i-rheumatoid arthritis noma i-psoriasis, udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi womuthi futhi akhuphule kancane umthamo wakho. Udokotela wakho futhi anganciphisa umthamo wakho uma uhlangabezana nemiphumela emibi yomuthi. Tshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa.

ICyclosporine (iguqulwe) isiza ukulawula izimpawu ze-psoriasis nesifo samathambo, kepha ayizelaphi lezi zimo. Uma uthatha i-cyclosporine (modified) ukwelapha i-psoriasis, kungathatha amasonto ama-2 noma ngaphezulu ukuthi izimpawu zakho ziqale ukuthuthuka, kanye namasonto ayi-12 kuye kwayi-16 ukuze uzwe umuzwa ophelele womuthi. Uma uthatha i-cyclosporine (modified) ukwelapha i-rheumatoid arthritis, kungathatha amasonto ama-4 kuye kwayi-8 ukuze izimpawu zakho zithuthuke. Qhubeka nokuthatha i-cyclosporine (modified) noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-cyclosporine (modified) ngaphandle kokukhuluma nodokotela wakho. Udokotela wakho anganciphisa umthamo wakho kancane kancane.

Ungabona iphunga elingavamile lapho uvula ikhadi le-blister lamaphilisi we-cyclosporine. Lokhu kujwayelekile futhi akusho ukuthi umuthi ulimele noma awuphephile ukuwusebenzisa.

Isixazululo somlomo seCyclosporine (esishintshiwe) singakha ijeli noma sibe nesigaxa uma sichayeka emazingeni okushisa angaphansi kuka-68 ° F (20 ° C). Ungasebenzisa isixazululo noma ngabe sifake ijeli, noma isisombululo ungasibuyisela kuketshezi ngokulivumela lifudumale ekamelweni lokushisa (77 ° F [25 ° C]).

Isixazululo somlomo seCyclosporine ne-cyclosporine (modified) kufanele sixutshwe noketshezi ngaphambi kokusetshenziswa. Isixazululo somlomo seCyclosporine (modified) singaxubana nejusi lewolintshi noma ijusi le-apula kepha akufanele sixutshwe nobisi. Isixazululo somlomo seCycosporine singaxubeka nobisi, ubisi lukashokoledi, noma ijusi lewolintshi. Kufanele ukhethe isiphuzo esisodwa ohlwini olufanele futhi njalo hlanganisa imithi yakho nalesi siphuzo.

Ukuthatha noma yiluphi uhlobo lwesisombululo somlomo, landela lezi zinyathelo:

• Gcwalisa inkomishi yengilazi (hhayi epulasitiki) ngesiphuzo osikhethile.
• Susa ikhava evikelayo ngaphezulu kwesirinji yokulinganisa eyeza nemithi yakho.
• Faka ichopho lesiponji ebhodleleni lesisombululo bese ubuyela emuva ku-plunger ukuze ugcwalise isipetu ngenani lesisombululo udokotela wakho asinike sona.
• Bamba isirinji phezu ketshezi engilazini yakho bese ucindezela phansi ku-plunger ukuze ubeke umuthi engilazini.
• Hlanganisa kahle ingxube.
• Phuza lonke uketshezi olusengilazini ngokushesha.
• Thela okuthe xaxa kwesiphuzo osikhethile engilazini, uzulazule ingilazi ukuze uyihlanze, bese uphuza uketshezi.
• Yomisa ingaphandle lesirinji ngethawula elihlanzekile bese ushintsha ikhava evikelayo. Musa ukugeza isirinji ngamanzi. Uma udinga ukugeza isirinji, qiniseka ukuthi somile ngokuphelele ngaphambi kokuyisebenzisa ukukala omunye umthamo.

I-Cyclosporine ne-cyclosporine (iguquliwe) kwesinye isikhathi isetshenziselwa ukwelapha isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lomgudu wokugaya ukudla, ubangele ubuhlungu, isifo sohudo, ukuncipha komzimba nomkhuhlane) nokuvikela ukwenqatshwa kweziguli ezithole amanyikwe noma ukufakelwa kwe-cornea. Khuluma nodokotela wakho mayelana nezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa. Buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-cyclosporine noma i-cyclosporine (modified),

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-cyclosporine, cyclosporine (modified), noma imuphi omunye umuthi, noma iziphi izithako ezingasebenzi ku-cyclosporine noma i-cyclosporine (modified) capsules noma isixazululo. Buza usokhemisi wakho ukuthola uhlu lwezithako ezingasebenzi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo, noma ohlela ukuzithatha. Qiniseka ukuthi uyayisho imithi efakwe kuhlu esigabeni ESIBALULEKILE SESEXWAYISO nanoma yikuphi okulandelayo: i-acyclovir (iZovirax); i-allopurinol (iZyloprim); i-amiodarone (iCordarone); i-angiotensin-converting enzyme (ACE) inhibitors efana ne-benazepril (Lotensin), i-captopril (i-Capoten), i-enalapril (i-Vasotec), i-fosinopril (i-Monopril), i-lisinopril (i-Prinivil, i-Zestril), i-moexipril (i-Univasc), i-perindopril) ), i-ramipril (i-Altace), ne-trandolapril (i-Mavik); ama-angiotensin II receptor antagonists afana ne-candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), ne-valsartan (Diovan); imishanguzo ethile yokulwa nobuthi efana ne-fluconazole (i-Diflucan), ne-itraconazole (i-Sporanox); i-azithromycin (iZithromax); i-bromocriptine (Parlodel); ama-calcium channel blocker afana ne-diltiazem (Cardizem), nicardipine (Cardene), ne-verapamil (Calan); carbamazepine (Tegretol); imithi yokwehlisa i-cholesterol (ama-statins) njenge-atorvastatin (Lipitor), i-fluvastatin (i-Lescol), i-lovastatin (i-Mevacor), i-pravastatin (i-Pravachol), ne-simvastatin (i-Zocor); i-clarithromycin (i-Biaxin); inhlanganisela ye-dalfopristin ne-quinupristin (Synercid); i-danazol; i-digoxin (i-Lanoxin); ama-diuretics athile ('amaphilisi amanzi') afaka i-amiloride (Midamor), i-spironolactone (i-Aldactone), ne-triamterene (i-Dyazide); i-erythromycin; I-HIV protease inhibitors efana ne-indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, eKaletra), ne-saquinavir (Fortovase); imatinib (Gleevec); i-metoclopramide (Reglan); i-methylprednisolone (iMedrol); nafcillin; i-octreotide (iSandostatin); izinto zokuvimbela inzalo ngomlomo (amaphilisi okuvimbela inzalo); i-orlistat (i-Xenical); i-phenobarbital; i-phenytoin (iDilantin); izithako ze-potassium; i-prednisolone (i-Pediapred); i-repaglinide (Prandin); i-rifabutin (i-Mycobutin); i-rifampin (i-Rifadin, i-Rimactane); i-sulfinpyrazone (i-Anturane); i-terbinafine (iLamisil); kanye ne-ticlopidine (Ticlid). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha i-sirolimus (Rapamune), yithathe amahora amane ngemuva kokuthatha i-cyclosporine noma i-cyclosporine (iguquliwe).
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• Tshela udokotela wakho uma ngabe uke waba nanoma yimiphi imibandela eshiwo esigabeni ESIBALULEKILE SESEXWAYISO noma okunye kwalokhu okulandelayo: i-cholesterol ephansi, amazinga aphansi we-magnesium egazini lakho, noma isiphi isimo esenza kube nzima emzimbeni wakho ukumunca izakhamzimba, noma isifo sesibindi.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha noma yiluphi uhlobo lwe-cyclosporine, shayela udokotela wakho. Zombili izinhlobo ze-cyclosporine zingakhuphula ubungozi bokuthi ingane yakho izalwe kusenesikhathi.
• tshela udokotela wakho uma uncelisa noma uhlela ukuncelisa.
• ungabi nayo imigomo ngaphandle kokukhuluma nodokotela wakho.
• kufanele wazi ukuthi i-cyclosporine ingadala ukukhula kwezicubu ezengeziwe ezinsinini zakho. Qiniseka ukuthi uxubha amazinyo akho ngokucophelela futhi ubone udokotela wamazinyo njalo ngesikhathi sokwelashwa kwakho ukunciphisa ingozi yokuthi uzoba nalo mphumela ohlangothini.

Gwema ukuphuza ujusi wamagilebhisi noma udle izithelo zomvini ngenkathi uthatha i-cyclosporine noma i-cyclosporine (modified).

Udokotela wakho angakutshela ukuthi ulinganisele inani le-potassium ekudleni kwakho. Landela le miyalo ngokucophelela. Khuluma nodokotela wakho ngenani lokudla okune-potassium eningi njengobhanana, umlimi unquma, omisiwe nejusi le-orange ongahle ube nalo ekudleni kwakho. Izinhlobo eziningi zikasawoti zine-potassium, ngakho-ke khuluma nodokotela wakho ngokuzisebenzisa ngesikhathi sokwelashwa kwakho.

Uma ukhohlwa ukuthatha umthamo, thatha isilinganiso esilahlekile ngokushesha nje lapho usikhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Cyclosporine ne-cyclosporine (modified) kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isifo sohudo
• isilungulela
• igesi
• ukukhula kwezinwele ukukhula ebusweni, ezingalweni noma emuva
• ukukhula kwezicubu ezengeziwe ezinsinini
• induna
• ukuqhuma
• ukuzamazama okungalawuleki kwengxenye yomzimba wakho
• ukushisa noma ukuncinza ezandleni, ezingalweni, ezinyaweni, noma emilenzeni
• ubuhlungu bemisipha noma bamalunga
• amajaqamba
• ubuhlungu noma ingcindezi ebusweni
• izinkinga zezindlebe
• ukukhuliswa kwamabele emadodeni
• ukudana
• ubunzima bokulala noma ukulala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukopha okungajwayelekile noma ukulinyazwa
• isikhumba esiphaphathekile
• ukuphuzi kwesikhumba noma kwamehlo
• isithuthwane
• ukulahlekelwa ukwazi
• izinguquko ekuziphatheni noma kwemizwa
• ubunzima bokulawula ukunyakaza komzimba
• izinguquko embonweni
• ukudideka
• ukuqubuka
• amabala ansomi esikhunjeni
• ukuvuvukala kwezandla, izingalo, izinyawo, amaqakala, noma imilenze engezansi

I-Cyclosporine ne-cyclosporine (modified) kungadala eminye imiphumela emibi. Khuluma nodokotela wakho uma uhlangabezana nezinkinga ezingavamile ngenkathi usebenzisa umuthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivaliwe futhi ayifinyeleleki ezinganeni. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungawugcini lo muthi esiqandisini futhi ungawumisi. Lahla noma yisiphi isisombululo esisele ezinyangeni ezimbili ngemuva kokuqala ukuvula ibhodlela.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukuphuzi kwesikhumba noma kwamehlo
• ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi.

Ungavumeli omunye umuntu athathe umuthi wakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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