Ezetimibe

-Delile

• Ngaphambi kokuthatha i-ezetimibe,
• I-Ezetimibe ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Izimpawu ezilandelayo azivamile, kepha uma uhlangabezana nenye yazo, shayela udokotela wakho ngokushesha:

I-Ezetimibe isetshenziswa kanye nezinguquko zendlela yokuphila (ukudla, ukwehlisa isisindo, ukuvivinya umzimba) ukwehlisa inani le-cholesterol (into efana namafutha) nezinye izinto ezinamafutha egazini. Ingasetshenziswa yodwa noma ihlanganiswe ne-HMG-CoA reductase inhibitor (statin). U-Ezetimibe usesigabeni semithi ebizwa ngemithi yokwehlisa i-cholesterol. Isebenza ngokuvimbela ukumuncwa kwe-cholesterol emathunjini.

Ukwakhiwa kwe-cholesterol namafutha eduze kwezindonga zemithambo yegazi (inqubo eyaziwa njenge-atherosclerosis) kunciphisa ukugeleza kwegazi, okwehlisa ukunikezwa komoya-mpilo enhliziyweni, ebuchosheni nakwezinye izingxenye zomzimba. Ukwehlisa amazinga egazi we-cholesterol namafutha kungasiza ekunciphiseni lokhu kwakha futhi kunganciphisa amathuba akho okuthuthukisa izimo zenhliziyo ezifana ne-angina (ubuhlungu besifuba), imivimbo nokuhlaselwa yinhliziyo. Imiphumela yocwaningo lomtholampilo oluqhathanisa abantu abathathe i-ezetimibe ne-simvastatin nabantu abathathe i-simvastatin bodwa bathola ukuthi yize iqembu labantu abathatha i-ezetimibe ne-simvastatin linamanani aphansi we-cholesterol egazini, bekungekho mehluko phakathi kwala maqembu womabili kunani we-cholesterol nokwakhiwa kwamafutha ngaphakathi kwemithambo yegazi entanyeni. Okwamanje akuqondakali ukuthi kungani ukwehliswa okwengeziwe kwamazinga e-cholesterol egazini kungazange kuholele ekwehleni okukhulu kwe-cholesterol nokwakhiwa kwamafutha ezindongeni zemithambo yegazi kubantu abathatha i-ezetimibe ne-simvastatin. Ezinye izifundo ziyaqhubeka ukuqhathanisa ukwelashwa ne-ezetimibe ne-simvastatin ekwelashweni nge-simvastatin kuphela ukubona ukuthi kukhona yini umehluko engcupheni yokuhlaselwa yisifo senhliziyo. Khuluma nodokotela wakho uma unemibuzo mayelana nobungozi nezinzuzo zokwelapha inani elinyukayo le-cholesterol egazini lakho nge-ezetimibe neminye imithi.

Ngaphezu kokuthatha umuthi owehlisa i-cholesterol, ukwenza izinguquko ezithile emikhubeni yakho yansuku zonke kunganciphisa namazinga we-cholesterol egazini lakho. Kufanele udle ukudla okunamafutha amancane ne-cholesterol egcwele (bheka IDIJITHI EYODWA); ukuzivocavoca imizuzu engama-30 ezinsukwini eziningi, uma kungezona zonke; futhi unciphise isisindo uma ukhuluphele ngokweqile.

U-Ezetimibe uza njengethebhulethi azoyithatha ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Ukukusiza ukuthi ukhumbule ukuthatha i-ezetimibe, yithathe ngesikhathi esifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-ezetimibe njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Qhubeka uthathe i-ezetimibe noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-ezetimibe ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-ezetimibe,

• Tshela udokotela kanye nosokhemisi wakho uma une-allergies ku-ezetimibe noma omunye umuthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela nemishanguzo ongayinikiwe, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyiphuzayo. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-anticoagulants (’’ ama-thinner egazi ’’) njenge-warfarin (i-Coumadin); i-cyclosporine (iNeoral, iSandimmune); i-fenofibrate (TriCor); futhi gemfibrozil (Lopid). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha i-cholestyramine (i-Questran), i-colesevelam (i-WellChol), noma i-colestipol (i-Colestid), thatha amahora amane ngaphambi noma amahora amabili ngemuva kwe-ezetimibe.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-ezetimibe, shayela udokotela wakho.

Yidla ukudla okunamafutha aphansi, okunamafutha amancane. Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo. Ungavakashela futhi iwebhusayithi ye-National Cholesterol Education Program (NCEP) ukuthola eminye imininingwane yokudla ku-http: //www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Ezetimibe ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isiyezi
• isifo sohudo
• Umphimbo obuhlungu
• ikhala eligijimayo
• ukuthimula
• ubuhlungu obuhlangene

Eminye imiphumela emibi ingaba mibi. Izimpawu ezilandelayo azivamile, kepha uma uhlangabezana nenye yazo, shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• isisu esibuhlungu
• ukukhathala ngokweqile
• ukopha okungajwayelekile noma ukulinyazwa
• ukungabi namandla
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• izimpawu ezinjengomkhuhlane
• ubuhlungu bemisipha noma ubuthakathaka
• imfiva
• Ukugodola
• indle ephaphathekile noma enamafutha
• ubuhlungu besifuba

I-Ezetimibe ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa ukuze ahlole impendulo yomzimba wakho ku-ezetimibe.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Zetia^®

• I-Liptruzet^® (equkethe i-Atorvastatin, Ezetimibe)
• I-Nexlizet^® (equkethe iBempedoic Acid, Ezetimibe)
• UVytorin^® (equkethe i-Ezetimibe, Simvastatin)