Miglustat

-Delile

• Ngaphambi kokuthatha i-miglustat,
• I-Miglustat ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Izimpawu ezilandelayo azivamile, kepha uma uhlangabezana nenye yazo, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

IMiglustat isetshenziselwa ukwelapha uhlobo lwesifo i-Gaucher 1 (isimo lapho into ethile enamafutha ingaphuli ngokwejwayelekile emzimbeni futhi kunalokho yakha kwezinye izitho futhi ibangele izinkinga zesibindi, ubende, amathambo negazi). UMiglustat usesigabeni semithi ebizwa ngama-enzyme inhibitors. Isebenza ngokuvimbela umzimba ukuthi ungakhiqizi into enamafutha ukuze kuncane okuzokwakha emzimbeni futhi kudale izimpawu.

IMiglustat iza njengephilisi elizothathwa ngomlomo. Imvamisa iphuzwa nokudla noma ngaphandle kokudla namanzi amaningi kuze kube kathathu ngosuku. Ukukusiza ukuthi ukhumbule ukuthatha i-miglustat, yithathe cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-miglustat njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

IMiglustat ilawula isifo seGaucher kepha ayiselaphi. Qhubeka nokuthatha i-miglustat noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-miglustat ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-miglustat,

• Tshela udokotela wakho kanye nosokhemisi uma une-aleji ku-miglustat, noma imiphi eminye imithi, noma imikhiqizo ye-soy.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela nemishanguzo ongayinikiwe, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyiphuzayo. Qiniseka ukusho imiglucerase (Cerezyme). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waqubuka noma wake waqubuka (ukuxhawula izandla ongakwazi ukuzilawula); ubuhlungu, ukuvutha, ukushoshozela, noma ukuba ndikindiki ezandleni noma ezinyaweni zakho; noma yisiphi isifo esithinta isistimu yakho yezinzwa; noma isifo sezinso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Kufanele usebenzise ukulawulwa kokubeletha okusebenzayo ukuvimbela ukukhulelwa ngenkathi uthatha i-miglustat. Uma ukhulelwa ngenkathi uthatha i-miglustat, shayela udokotela wakho ngokushesha. I-Miglustat ingalimaza umbungu.
• kufanele wazi ukuthi i-miglustat ingalimaza isidoda. Abesilisa abathatha i-miglustat kufanele basebenzise ukulawulwa kokubeletha okusebenzayo ngenkathi belashwa nangezinyanga ezintathu ngemuva kwalokho.

I-Miglustat ingadala isifo sohudo kanye nokwehla kwesisindo. Uma uhlangabezana nale miphumela emibi, udokotela wakho uzokutshela ukuthi ungakushintsha kanjani ukudla kwakho ukuze uthuthukise izimpawu zakho. Ungatshelwa ukuthi ugweme ukudla okunama-carbohydrate amaningi. Landela le miyalo ngokucophelela.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Miglustat ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ubuhlungu besisu noma ukuqunjelwa
• igesi
• ukulahlekelwa isifiso sokudla
• ukuncipha komzimba
• isisu esibuhlungu
• ukuhlanza
• ukuqunjelwa
• ukugaya ukudla
• umlomo owomile
• ubuthakathaka
• amajaqamba, ikakhulukazi emilenzeni
• umuzwa wobunzima ezingalweni noma emilenzeni
• ukungazinzi lapho uhamba
• ukuhlungu obusemhlane
• isiyezi
• uvalo
• ikhanda
• izinkinga zememori
• ukuya esikhathini okunzima noma okungajwayelekile (isikhathi)

Eminye imiphumela emibi ingaba mibi. Izimpawu ezilandelayo azivamile, kepha uma uhlangabezana nenye yazo, shayela udokotela wakho ngokushesha:

• ubuhlungu, ukuvutha, ukuba ndikindiki noma ukuncinza ezandleni zakho, izingalo, imilenze noma izinyawo
• ukuxhawula izandla ongeke ukwazi ukuzilawula
• izinguquko embonweni
• ukulinyazwa okulula noma ukopha

IMiglustat ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ubuhlungu, ukushisa, ukugedlezela, noma ukuba ndikindiki ezandleni zakho, ezingalweni, emilenzeni, noma ezinyaweni
• umphimbo obuhlungu, umkhuhlane, ukubanda, noma ezinye izimpawu zokutheleleka
• isiyezi

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Zavesca^®