Inaliti ye-Apomorphine

-Delile

• Ngaphambi kokusebenzisa umjovo we-apomorphine,
• Umjovo we-Apomorphine ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo we-Apomorphine usetshenziselwa ukwelapha iziqephu (`` zokuvala '' (izikhathi zobunzima bokuhamba, ukuhamba, nokukhuluma okungenzeka njengoba umuthi uphela noma ngokungahleliwe) kubantu abanesifo seParkinson's advanced (PD; ukuphazamiseka kwesistimu yezinzwa okubanga ubunzima ngokunyakaza, ukulawula imisipha, nokulinganisela) abathatha eminye imithi ngesimo sabo. Umjovo we-Apomorphine usesigabeni semithi ebizwa ngama-dopamine agonists. Isebenza ngokusebenza esikhundleni se-dopamine, into yemvelo ekhiqizwa ebuchosheni edingekayo ukulawula ukunyakaza.

I-Apomorphine iza njengesisombululo sokujova ngomgogodla (ngaphansi nje kwesikhumba). I-Apomorphine ivamise ukujova lapho idingeka, ngokuyalelwa ngudokotela wakho. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-apomorphine njengoba uqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Ungasebenzisi umthamo wesibili womjovo we-apomorphine ekwelapheni isiqephu esifanayo "sokucisha". Linda okungenani amahora ama-2 phakathi kwamanani.

Udokotela wakho uzokunikeza omunye umuthi obizwa nge-trimethobenzamide (Tigan) ozowuthatha lapho uqala ukusebenzisa umjovo we-apomorphine. Le mithi izosiza ukunciphisa amathuba akho okuthuthukisa isicanucanu nokuhlanza ngenkathi usebenzisa umjovo we-apomorphine, ikakhulukazi ngesikhathi sokuqala kokwelashwa. Udokotela wakho mhlawumbe uzokutshela ukuthi uqale ukuthatha i-trimethobenzamide ezinsukwini ezimbalwa ngaphambi kokuba uqale ukusebenzisa umjovo we-apomorphine, futhi uqhubeke nokuyiphuza izinyanga ezi-2. Kufanele wazi ukuthi ukuthatha i-trimethobenzamide kanye nomjovo we-apomorphine kungakhulisa ubungozi bakho ukozela, isiyezi nokuwa. Kodwa-ke, ungayeki ukuthatha i-trimethobenzamide ngaphandle kokukhuluma nodokotela wakho kuqala.

Udokotela wakho kungenzeka akuqale ngomthamo ophansi womjovo we-apomorphine futhi akhuphule kancane umthamo wakho, hhayi ngaphezu kwesisodwa njalo ezinsukwini ezimbalwa. Buza udokotela wakho ukuthi wenzeni uma ungasebenzisi umjovo we-apomorphine isikhathi esingaphezu kwesonto elilodwa. Udokotela wakho mhlawumbe uzokutshela ukuthi uqale kabusha le mithi usebenzisa umthamo ophansi futhi wandise kancane kancane umthamo wakho.

Isixazululo se-Apomorphine siza ngegobolondo lengilazi elizosetshenziswa ngepeni lokujova. Ezinye izinaliti zinikezwa ipeni lakho kanti ezinye izinaliti zithengiswa ngokwehlukana. Buza udokotela noma usokhemisi wakho uma unemibuzo ngohlobo lwenaliti oyidingayo. Njalo sebenzisa inaliti entsha, oyinyumba ngomjovo ngamunye. Ungalokothi usebenzise izinaliti, futhi ungalokothi uvumele inaliti ithinte noma iyiphi indawo ngaphandle kwendawo lapho uzofaka khona umuthi. Ungalokothi ugcine noma uphathe ipeni lokujova ngenaliti enamathiselwe. Lahla izinaliti esitsheni esimelana nokubhoboza okugcinwe lapho izingane zingafinyeleleki khona. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Uzothola isilinganiso sakho sokuqala somjovo we-apomorphine ehhovisi lezokwelapha lapho udokotela wakho ezokwazi ukuqapha khona kakhulu isimo sakho. Ngemuva kwalokho, udokotela wakho angakutshela ukuthi ungakwazi ukujova i-apomorphine ngokwakho noma umngani noma isihlobo abakujove. Ngaphambi kokusebenzisa umjovo we-apomorphine ngokwakho okokuqala, funda imiyalelo ebhaliwe eza nayo. Buza udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozobe ejova umuthi ukuthi ungawujova kanjani.

Qiniseka ukuthi uyazi ukuthi yiziphi izinombolo esibayeni se-injector ezibonisa umthamo wakho. Kungenzeka ukuthi udokotela wakho ukutshele ukuthi udinga ukusebenzisa ama-milligram amangaki, kodwa ipeni limakwe ngamamililitha. Buza udokotela wakho noma usokhemisi uma ungaqiniseki ukuthi ungawuthola kanjani umthamo wakho epeni lokujova.

Ipeni lokujova i-apomorphine lisetshenziselwa umuntu oyedwa kuphela. Ungabelani ngepeni lakho nanoma ngubani.

Qikelela ukuthi ungawutholi umjovo we-apomorphine esikhunjeni sakho noma emehlweni akho. Uma umjovo we-apomorphine ufika esikhunjeni sakho noma emehlweni akho, masisha ugeze isikhumba sakho noma uvule amehlo akho ngamanzi abandayo.

Ungafaka i-apomorphine endaweni yakho yesisu, ingalo ephezulu, noma umlenze ongaphezulu. Musa ukujova emthanjeni noma endaweni lapho isikhumba sinobuhlungu, sibomvu, silimele, sinezibazi, sinegciwane, noma singajwayelekile nganoma iyiphi indlela. Sebenzisa indawo ehlukile yomjovo ngamunye, ukhetha phakathi kwamabala otshelwe ukuthi uwasebenzise. Gcina irekhodi losuku nendawo yomjovo ngamunye. Ungasebenzisi indawo efanayo izikhathi ezimbili zilandelana.

Njalo bheka isisombululo sakho se-apomorphine ngaphambi kokusijova. Kufanele icace, ingenambala, futhi ingabi nezinhlayiya. Ungayisebenzisi i-apomorphine uma inamafu, iluhlaza okotshani, iqukethe izinhlayiya, noma uma usuku lokuphelelwa yisikhathi kwikhathoni seludlulile.

Gcina irekhodi lokuthi ungakanani umjovo we-apomorphine owusebenzisa njalo lapho uthola umjovo ukuze wazi ukuthi uyibuyisela nini igobolondo lemithi.

Ungahlanza ipeni lakho lokujova i-apomorphine ngendwangu emanzi lapho kudingeka. Ungalokothi usebenzise izibulala-magciwane ezinamandla noma ugeze ipeni lakho ngaphansi kwamanzi agobhozayo.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-apomorphine,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-apomorphine, noma imiphi eminye imithi, ama-sulfite, noma ezinye izithako zomjovo we-apomorphine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-alosetron (Lotronex), i-dolasetron (i-Anzemet), i-granisetron (i-Sancuso), i-ondansetron (i-Zofran), noma i-palonosetron (i-Aloxi). Udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi umjovo we-apomorphine uma usebenzisa omunye wale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: ukungezwani komzimba, ukukhwehlela nemithi ebandayo; i-amiodarone (i-Nexterone, i-Pacerone); imishanguzo; ama-antihistamine; i-chlorpromazine; i-disopyramide (iNorpace); i-dofetilide (Tikosyn); i-erythromycin (E.E.S.); i-haloperidol (iHaldol); imithi yokwelapha ukugula kwengqondo, isisu esicasulayo, isifo senhliziyo, umfutho wegazi ophakeme, ubuhlungu, noma ukuquleka; i-metoclopramide (Reglan); moxifloxacin (Avelox); ukuphumula kwemisipha; eminye imithi yesifo sikaParkinson; ipimozide (i-Orap); procainamide; iprochlorperazine (Compro); i-promethazine; i-quinidine (ku-Nuedexta); isidambisi; i-sildenafil (i-Viagra, i-Revatio); amaphilisi okulala; i-sotalol (iBetapace); i-tadalafil (i-Cialis); okokunciphisa umzimba; i-vardenafil (i-Levitra); noma ama-nitrate afana ne-isosorbide dinitrate (Isordil, e-Bidil), isosorbide mononitrate (Monoket), noma i-nitroglycerin (Nitro-Dur, Nitrostat, abanye). Ama-nitrate eza njengamathebulethi, ama-tablet (ngaphansi kolimi) amaphilisi, izifutho, ama-patches, ama-pastes, namafutha. Buza udokotela wakho uma ungaqiniseki ukuthi ikhona yini imithi yakho equkethe ama-nitrate. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• kufanele wazi ukuthi uma uthatha i-nitroglycerin ngaphansi kolimi lwakho ngenkathi usebenzisa umjovo we-apomorphine, umfutho wegazi lakho ungancipha futhi ubangele isiyezi. Ngemuva kokuthatha amaphilisi e-nitroglycerin ngaphansi kolimi lwakho, kufanele ulale phansi okungenani imizuzu engama-45 futhi ugweme ukuma ngalesi sikhathi.
• utshele udokotela wakho uma uphuza utshwala noma uma uke waphathwa yisifuba somoya; isiyezi; ukuquleka; ukushaya kwenhliziyo okuhamba kancane noma okungajwayelekile; umfutho wegazi ophansi; amazinga aphansi we-potassium noma i-magnesium egazini; ukugula ngengqondo; ukuphazamiseka kokulala; isifo sohlangothi, ukushaywa unhlangothi, noma ezinye izinkinga zobuchopho; ukunyakaza okungalawuleki okungazelelwe nokuwa; noma isifo senhliziyo, sezinso, noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-apomorphine, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa umjovo we-apomorphine.
• kufanele wazi ukuthi umjovo we-apomorphine ungakwenza ukozele. Ungashayeli imoto, sebenzisa imishini, noma wenze noma yini engakubeka engcupheni yokulimala uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi ungazuma ngokuzumayo ngesikhathi semisebenzi yakho ejwayelekile yansuku zonke ngenkathi usebenzisa umjovo we-apomorphine. Ungahle ungazeli ukozela ngaphambi kokulala. Uma uvele ulale ngokuzumayo ngenkathi wenza umsebenzi wansuku zonke njengokudla, ukukhuluma, noma ukubukela ithelevishini, shayela udokotela wakho. Ungashayeli imoto noma usebenzise imishini uze ukhulume nodokotela wakho.
• akufanele uphuze utshwala ngenkathi usebenzisa umjovo we-apomorphine. Utshwala bungenza imiphumela emibi evela kumjovo we-apomorphine ibe yimbi kakhulu.
• kufanele wazi ukuthi abanye abantu abathathe imishanguzo efana nomjovo we-apomorphine baba nezinkinga zokugembula noma ezinye izifiso ezinamandla noma izindlela zokuziphatha ezazicindezela noma zingajwayelekile kubo, njengokunyuka kwezifiso zocansi noma isimilo. Akukho mininingwane eyanele yokutshela ukuthi ngabe abantu baba nezinkinga yini ngenxa yokuthi bathathe umuthi noma ngenxa yezinye izizathu. Shayela udokotela wakho uma unesifiso sokugembula okunzima ukusilawula, unezikhalazo ezinkulu, noma awukwazi ukulawula ukuziphatha kwakho. Tshela amalungu omndeni wakho ngale ngozi ukuze bakwazi ukubiza udokotela noma ngabe awuboni ukuthi ukugembula kwakho noma yiziphi ezinye izifiso ezinamandla noma ukuziphatha okungajwayelekile kube yinkinga.
• kufanele wazi ukuthi umjovo we-apomorphine ungadala isiyezi, ikhanda elikhanyayo, isicanucanu, ukujuluka, nokuquleka lapho uvuka ngokushesha okukhulu endaweni yokulala noma yokuhlala. Lokhu kuvame kakhulu lapho uqala ukusebenzisa umjovo we-apomorphine noma ulandela ukwanda komthamo. Ukugwema le nkinga, vuka embhedeni noma uvuke endaweni yokuhlala kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Lo muthi uvame ukusetshenziswa lapho kudingeka.

Umjovo we-Apomorphine ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukuqunjelwa
• isifo sohudo
• ikhanda
• kuzamula
• ikhala eligijimayo
• ubuthakathaka
• ingalo, umlenze, noma ubuhlungu beqolo
• ubuhlungu noma ubunzima ekuchameni
• ukudabuka, ububomvu, ubuhlungu, ukulimaza, ukuvuvukala, noma ukulunywa endaweni lapho ufake khona i-apomorphine

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka; isifuba; ukulunywa; ukuvuvukala kobuso, umphimbo, ulimi, izindebe, noma amehlo; ubunzima bokuphefumula nokugwinya; ukuphefumula, ukukhwehlela; noma ukusha
• ukushaya kwenhliziyo okusheshayo noma okushaya ngamandla
• ubuhlungu besifuba
• ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
• ukulinyazwa
• ukunyakaza okungalawuleki okungazelelwe
• Iwela phansi
• ukubona izinto ezingekho (ukubona izinto noma ukuzwa amazwi angekho), isimilo esinolaka, ukukhathazeka, ukuzizwa njengabantu abamelene nawe, noma imicabango engahlelekile
• ukudana
• imfiva
• ukudideka
• ukwakhiwa okubuhlungu okungapheli

Ezinye izilwane zaselabhorethri ezanikezwa umjovo we-apomorphine zaba nesifo samehlo. Akwaziwa ukuthi umjovo we-apomorphine unyusa ingozi yesifo samehlo kubantu. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi.

I-Apomorphine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi ku-cartridge ifike futhi ingafinyeleleki ezinganeni. Kugcine esikhwameni sokuphatha ekamelweni lokushisa kude nokukhanya, ukushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ukuquleka
• isiyezi
• ukungaboni kahle
• ukushaya kwenhliziyo okuhamba kancane
• isimilo esingajwayelekile
• ukusangana
• ukunyakaza okungalawuleki okungazelelwe

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Apokyn^®