Bortezomib

-Delile

• Ngaphambi kokusebenzisa i-bortezomib,
• I-Bortezomib ingadala imiphumela emibi. Tshela udokotela wakho uma ngabe enye yalezi zimpawu, noma lezo esigabeni esikhethekile SOKUQAPHA, zinzima noma zingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Bortezomib isetshenziselwa ukwelapha abantu abane-myeloma eminingi (uhlobo lomdlavuza womnkantsha wethambo). I-Bortezomib isetshenziselwa ukwelapha abantu abane-mantle cell lymphoma (umdlavuza okhula ngokushesha oqala kumaseli amasosha omzimba). I-Bortezomib isekilasini lemithi ebizwa ngama-antineoplastic agents. Isebenza ngokubulala amangqamuzana omdlavuza.

IBortezomib iza njengesisombululo (uketshezi) ukujova emthanjeni noma ngaphansi (ngaphansi kwesikhumba). IBortezomib inikezwa ngudokotela noma umhlengikazi ehhovisi lezokwelapha noma emtholampilo. Isikhathi sakho sokulinganisa sizoncika esimweni onaso, eminye imithi oyisebenzisayo, nokuthi umzimba wakho uphendula kahle kanjani ekwelashweni.

Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Udokotela wakho angamisa ukwelashwa kwakho isikhashana noma anciphise umthamo wakho we-bortezomib uma uthola imiphumela emibi yomuthi.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-bortezomib,

• Tshela udokotela wakho kanye nomhlinzeki wezokunakekelwa kwezempilo uma unegciwane ku-bortezomib, mannitol, noma imuphi omunye umuthi, i-boron, noma esinye sezithako e-bortezomib. Buza umhlinzeki wakho wezokunakekelwa kwezempilo ngohlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela noma engabhaliswanga, amavithamini, noma izithako zokudla okunempilo ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-clarithromycin (i-Biaxin, ku-PrevPac); ama-antifungal afana ne-itraconazole (Sporanox) noma i-ketoconazole (i-Nizoral); idelalisib (iZydelig); imithi yokwelapha isifo sikashukela noma umfutho wegazi ophakeme; imishanguzo ethile yokwelapha igciwane lesandulela ngculazi (i-HIV) noma i-immunodeficiency syndrome (i-AIDS) efana ne-indinavir (Crixivan), i-nelfinavir (i-Viracept), i-ritonavir (i-Norvir), noma i-saquinavir (i-Invirase); imithi ethile yokwelapha ukuquleka okufana ne-carbamazepine (Carbatrol, Tegretol), phenobarbital (Luminal, Solfoton), noma phenytoin (Dilantin, Phenytek); nefazodone; i-ribociclib (Kisqali, Kisqali, ku-Femera); i-rifabutin (i-Mycobutin); noma i-rifampin (Rifadin, Rifamate, Rimactane, abanye). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-bortezomib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• tshela udokotela wakho uma wena noma omunye emndenini wakho unesifo senhliziyo noma uke waba nokutheleleka kwe-herpes (izilonda ezibandayo, ama-shingles, noma izilonda zangasese); isifo sikashukela; ukuquleka; i-cholesterol ephezulu (amafutha egazini); umfutho wegazi ophansi noma ophakeme; i-peripheral neuropathy (ukundikindiki, ubuhlungu, ukugedlezela, noma umuzwa ovuthayo ezinyaweni noma ezandleni) noma ubuthakathaka noma ukulahlekelwa yimizwa noma ukucabanga engxenyeni yomzimba wakho; noma isifo sezinso noma sesibindi. Phinda utshele udokotela wakho uma ubhema noma uphuza utshwala obuningi.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. IBortezomib ingalimaza umbungu. Sebenzisa ukulawulwa kokuzalwa ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nge-bortezomib futhi okungenani izinyanga eziyi-7 ngemuva komthamo wakho wokugcina. Uma ungowesilisa onomlingani wesifazane ongakhulelwa, qiniseka ukusebenzisa ukulawulwa kokuzalwa ngesikhathi sokwelashwa kwakho nge-bortezomib futhi okungenani izinyanga ezine ngemuva komthamo wakho wokugcina. Buza udokotela wakho uma unemibuzo mayelana nezinhlobo zokulawulwa kokuzalwa okuzokusebenzela. Uma wena noma umlingani wakho ukhulelwa ngenkathi usebenzisa i-bortezomib noma izinyanga eziyi-7 ngemuva komthamo wakho wokugcina, shayela udokotela wakho ngokushesha.
• ungancelisi ibele ngesikhathi sokwelashwa kwakho nge-bortezomib nangezinyanga ezimbili ngemuva komthamo wakho wokugcina.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-bortezomib.
• kufanele wazi ukuthi i-bortezomib ingakwenza ukozele, ube nesiyezi, noma ube nekhanda elikhanyayo, noma ikwenze uphelelwe amandla noma ungaboni kahle. Ungashayeli imoto noma usebenzise imishini noma amathuluzi ayingozi uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi i-bortezomib ingadala isizungu, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu kusuka endaweni elele. Lokhu kuvame kakhulu kubantu asebeke baquleka esikhathini esedlule, abantu abaphelelwe amanzi emzimbeni, nabantu abathatha imishanguzo eyehlisa umfutho wegazi. Ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.

Khuluma nodokotela wakho mayelana nokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi usebenzisa lo muthi.

Phuza uketshezi oluningi nsuku zonke ngenkathi welashwa nge-bortezomib, ikakhulukazi uma uhlanza noma uhanjiswa yisisu.

Uma uphuthelwa i-aphoyintimenti ukuthola umthamo we-bortezomib, shayela udokotela wakho ngokushesha.

I-Bortezomib ingadala imiphumela emibi. Tshela udokotela wakho uma ngabe enye yalezi zimpawu, noma lezo esigabeni esikhethekile SOKUQAPHA, zinzima noma zingapheli:

• ubuthakathaka jikelele
• ukukhathala
• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• ubuhlungu besisu
• ikhanda
• ubuhlungu, ububomvu, ukulimaza, ukopha, noma ukuqina endaweni yokujova
• ubunzima bokulala noma ukulala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ubuthakathaka ezingalweni noma emilenzeni, ushintsho ngomqondo wokuthinta, noma ubuhlungu, ukushisa, ukuba ndikindiki, noma ukuncinza ezandleni, izingalo, imilenze, noma izinyawo
• ukudubula okungazelelwe noma ubuhlungu bokugwazwa, ubuhlungu obuhlala buhleli noma obushisayo, noma ubuthakathaka bemisipha
• ukuphefumula, ukushaya kwenhliziyo okusheshayo, ikhanda elibuhlungu, isiyezi, isikhumba esiphaphathekile, ukudideka, noma ukukhathala
• ukuvuvukala kwezinyawo, amaqakala, noma imilenze engezansi
• isifuba, ukuqubuka, ukulunywa
• ukudina, ubunzima bokugwinya noma ukuphefumula, noma ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, noma izandla
• umkhuhlane, umphimbo obuhlungu, amakhaza, ukukhwehlela noma ezinye izimpawu zokutheleleka
• ukulimaza noma ukopha okungavamile
• indle emnyama neyokulinda, igazi elibomvu kulindle, ukuhlanza okunegazi, noma okokuhlanza okubukeka njengezizathu zekhofi
• ukukhuluma okungaqondakali noma ukungakwazi ukukhuluma noma ukuqonda inkulumo, ukudideka, ukukhubazeka (ukulahlekelwa amandla okuhambisa ingxenye yomzimba), ukushintsha kombono, noma ukulahleka kombono, ibhalansi, ukuxhumanisa, inkumbulo noma ukwazi
• ukuquleka, ukungaboni kahle, isiyezi, isicanucanu, noma amajaqamba
• ukucindezela kwesifuba noma ubuhlungu, ukushaya kwenhliziyo okusheshayo, ukuvuvukala kwamaqakala noma izinyawo, noma ukuphefumula okuncane
• ukukhwehlela, ukuphefumula, ukuphefumula, noma ukuphefumula kanzima
• ikhanda, ukudideka, ukuqubuka, ukukhathala, noma ukulahleka kombono noma izinguquko
• amachashazi aluhlaza okwesibhakabhaka akhombe phansi okhomba isikhumba, umkhuhlane, ukukhathala, isiyezi, ukuphefumula okuncane, ukulimaza, ukudideka, ukulala, ukuqubuka, ukwehla kokuchama, igazi emchameni, noma ukuvuvukala kwemilenze
• umkhuhlane, ikhanda elibuhlungu, ukugodola, isicanucanu, ubuhlungu, ukulunywa noma ukuncinza okulandelwa ukuqubuka endaweni efanayo namabhamuza esikhumba alumayo noma abuhlungu
• isicanucanu, ukukhathala ngokweqile, ukopha okungavamile noma ukulimaza, ukungabi namandla, ukulahlekelwa isifiso sokudla, ubuhlungu engxenyeni engaphezulu yesisu, ukuphuzi kwesikhumba noma kwamehlo, noma izimpawu ezifana nomkhuhlane

I-Bortezomib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

IBortezomib izogcinwa ehhovisi lezokwelapha noma emtholampilo.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuquleka
• isiyezi
• ukungaboni kahle
• ukulimaza noma ukopha okungavamile

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zebhu ukuze ahlole impendulo yomzimba wakho ku-bortezomib.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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